TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković-Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5614
AB  - This study aimed to investigate the chemical composition of steam distillate essential oil
and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence
of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,
their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different
from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among
the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the
tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration
(MBC/MFC) were 14.20 and 28.4 µL mL−1
, respectively). MIC and MBC values of other tested
bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged
from 28.40/56.81 to 56.81–113.63 µL mL−1
. Antibiotic susceptibility patterns for the analyzed eight
respiratory-associated microorganisms showed an intermediate level of resistance to commonly used
antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the
antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess
remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an
alternative to conventional antibiotic therapy
PB  - MDPI
T2  - Processes
T1  - Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity
VL  - 10
IS  - 8
SP  - 1608
DO  - 10.3390/pr10081608
ER  - 

@article{
author = "Aćimović, Milica G. and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković-Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oil
and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence
of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,
their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different
from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among
the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the
tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration
(MBC/MFC) were 14.20 and 28.4 µL mL−1
, respectively). MIC and MBC values of other tested
bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged
from 28.40/56.81 to 56.81–113.63 µL mL−1
. Antibiotic susceptibility patterns for the analyzed eight
respiratory-associated microorganisms showed an intermediate level of resistance to commonly used
antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the
antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess
remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an
alternative to conventional antibiotic therapy",
publisher = "MDPI",
journal = "Processes",
title = "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity",
volume = "10",
number = "8",
pages = "1608",
doi = "10.3390/pr10081608"
}

Aćimović, M. G., Pezo, L., Čabarkapa, I., Trudić, A., Stanković-Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes
MDPI., 10(8), 1608.
https://doi.org/10.3390/pr10081608

Aćimović MG, Pezo L, Čabarkapa I, Trudić A, Stanković-Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes. 2022;10(8):1608.
doi:10.3390/pr10081608 .

Aćimović, Milica G., Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković-Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity" in Processes, 10, no. 8 (2022):1608,
https://doi.org/10.3390/pr10081608 . .

TY  - DATA
AU  - Aćimović, Milica G.
AU  - Pezo, Lato
AU  - Čabarkapa, Ivana
AU  - Trudić, Anika
AU  - Stanković-Jeremić, Jovana
AU  - Varga, Ana
AU  - Lončar, Biljana
AU  - Šovljanski, Olja
AU  - Tešević, Vele
PY  - 2022
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/5618
AB  - This study aimed to investigate the chemical composition of steam distillate essential oiland corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influenceof weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly differentfrom the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Amongthe eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to thetested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration(MBC/MFC) were 14.20 and 28.4 µL mL−1, respectively). MIC and MBC values of other testedbacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC rangedfrom 28.40/56.81 to 56.81–113.63 µL mL−1. Antibiotic susceptibility patterns for the analyzed eightrespiratory-associated microorganisms showed an intermediate level of resistance to commonly usedantibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to theantimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possessremarkable antibacterial activities and could be used to develop pharmaceutical formulations as analternative to conventional antibiotic therapy
PB  - MDPI
T2  - Processes
T1  - Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.
VL  - 10
IS  - 8
SP  - 1608
UR  - https://hdl.handle.net/21.15107/rcub_cherry_5618
ER  - 

@misc{
author = "Aćimović, Milica G. and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković-Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele",
year = "2022",
abstract = "This study aimed to investigate the chemical composition of steam distillate essential oiland corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influenceof weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly differentfrom the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Amongthe eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to thetested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration(MBC/MFC) were 14.20 and 28.4 µL mL−1, respectively). MIC and MBC values of other testedbacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC rangedfrom 28.40/56.81 to 56.81–113.63 µL mL−1. Antibiotic susceptibility patterns for the analyzed eightrespiratory-associated microorganisms showed an intermediate level of resistance to commonly usedantibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to theantimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possessremarkable antibacterial activities and could be used to develop pharmaceutical formulations as analternative to conventional antibiotic therapy",
publisher = "MDPI",
journal = "Processes",
title = "Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.",
volume = "10",
number = "8",
pages = "1608",
url = "https://hdl.handle.net/21.15107/rcub_cherry_5618"
}

Aćimović, M. G., Pezo, L., Čabarkapa, I., Trudić, A., Stanković-Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.. in Processes
MDPI., 10(8), 1608.
https://hdl.handle.net/21.15107/rcub_cherry_5618

Aćimović MG, Pezo L, Čabarkapa I, Trudić A, Stanković-Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608.. in Processes. 2022;10(8):1608.
https://hdl.handle.net/21.15107/rcub_cherry_5618 .

Aćimović, Milica G., Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković-Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Supplementary material for the article: Aćimović, M. G.; Pezo, L.; Čabarkapa, I.; Trudić, A.; Stanković-Jeremić, J.; Varga, A.; Lončar, B.; Šovljanski, O.; Tešević, V. Variation of Salvia Officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. Processes 2022, 10 (8), 1608. https://doi.org/10.3390/pr10081608." in Processes, 10, no. 8 (2022):1608,
https://hdl.handle.net/21.15107/rcub_cherry_5618 .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Ljujić, Jovana
AU  - Vulić, Jelena
AU  - Zheljazkov, Valtcho D.
AU  - Pezo, Lato
AU  - Varga, Ana
AU  - Tumbas Šaponjac, Vesna
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4609
AB  - H. italicum essential oil (EO) is one of the most popular ingredients utilized by the cosmetic industry, and it is also used as natural antioxidant and as a value-added ingredient in food products. The chemical composition of the EO H. italicum cultivated in Serbia was analyzed by gas chromatography–mass spectrometry. The quantitative structure–retention relationship was used to predict the retention indices of the EO constituents acquired by GC-MS data, applying five molecular descriptors selected by factor analysis and a genetic algorithm. Also, antimicrobial activity, and biological activity by four common antioxidant tests (DPPH and ABTS assays, reducing power, and β-carotene bleaching test), and in vitro antihyperglycemic and anti-inflammatory capacities were evaluated. A total of 70 EO constituents were detected, of which 17 (8.5%) could not be identified. The H. italicum EO in this study belonged to γ-curcumene chemotype. The coefficients of determination reached the value of 0.964, demonstrating that this model could be used for prediction purposes. All applied tests showed that H. italicum EO possesses good biological activity and an interesting chemical composition. Therefore, the EO of H. italicum grown in Serbia has a potential to be used in food, cosmetic, and pharmaceutical products.
PB  - MDPI
T2  - Agronomy
T2  - Agronomy
T1  - Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia?
VL  - 11
IS  - 7
SP  - 1282
DO  - 10.3390/agronomy11071282
ER  - 

@article{
author = "Aćimović, Milica G. and Ljujić, Jovana and Vulić, Jelena and Zheljazkov, Valtcho D. and Pezo, Lato and Varga, Ana and Tumbas Šaponjac, Vesna",
year = "2021",
abstract = "H. italicum essential oil (EO) is one of the most popular ingredients utilized by the cosmetic industry, and it is also used as natural antioxidant and as a value-added ingredient in food products. The chemical composition of the EO H. italicum cultivated in Serbia was analyzed by gas chromatography–mass spectrometry. The quantitative structure–retention relationship was used to predict the retention indices of the EO constituents acquired by GC-MS data, applying five molecular descriptors selected by factor analysis and a genetic algorithm. Also, antimicrobial activity, and biological activity by four common antioxidant tests (DPPH and ABTS assays, reducing power, and β-carotene bleaching test), and in vitro antihyperglycemic and anti-inflammatory capacities were evaluated. A total of 70 EO constituents were detected, of which 17 (8.5%) could not be identified. The H. italicum EO in this study belonged to γ-curcumene chemotype. The coefficients of determination reached the value of 0.964, demonstrating that this model could be used for prediction purposes. All applied tests showed that H. italicum EO possesses good biological activity and an interesting chemical composition. Therefore, the EO of H. italicum grown in Serbia has a potential to be used in food, cosmetic, and pharmaceutical products.",
publisher = "MDPI",
journal = "Agronomy, Agronomy",
title = "Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia?",
volume = "11",
number = "7",
pages = "1282",
doi = "10.3390/agronomy11071282"
}

Aćimović, M. G., Ljujić, J., Vulić, J., Zheljazkov, V. D., Pezo, L., Varga, A.,& Tumbas Šaponjac, V.. (2021). Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia?. in Agronomy
MDPI., 11(7), 1282.
https://doi.org/10.3390/agronomy11071282

Aćimović MG, Ljujić J, Vulić J, Zheljazkov VD, Pezo L, Varga A, Tumbas Šaponjac V. Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia?. in Agronomy. 2021;11(7):1282.
doi:10.3390/agronomy11071282 .

Aćimović, Milica G., Ljujić, Jovana, Vulić, Jelena, Zheljazkov, Valtcho D., Pezo, Lato, Varga, Ana, Tumbas Šaponjac, Vesna, "Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia?" in Agronomy, 11, no. 7 (2021):1282,
https://doi.org/10.3390/agronomy11071282 . .

TY  - JOUR
AU  - Aćimović, Milica G.
AU  - Todosijević, Marina
AU  - Varga, Ana
AU  - Kiprovski, Biljana
AU  - Tešević, Vele
AU  - Čabarkapa, Ivana
AU  - Sikora, Vladimir
PY  - 2019
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3926
AB  - Species of the Lamiaceae family have enjoyed a rich tradition of use for flavoring, food preservation, and medicinal purposes, due to their curative and preventive properties. Cultivated winter savory (Satureja montana L.), sage (Salvia officinalis L.) and hyssop (Hyssopus officinalis L.) are produced for seed, herb, and essential oil. Dominant compounds in S. montana essential oil were carvacrol (43.2%) and thymol (28.4%), while CIS-thujone (27.1%) and camphor (19.3%), followed by trans-thujone and 1,8-cineole were the major compounds in S. officinalis essential oil. As for H. officinalis essential oil, CIS-and trans-pinocamphone (41.1% and 20.5%, respectively) were the most abundant compounds, followed by b-pinene. S. montana essential oil exhibit the highest antimicrobial properties, as well as antioxidant capacity, compared to other tested essential oils. Furthermore, H. officinalis essential oils showed higher antioxidant activity than that of S. officinalis. The aim of this investigation was to determine the composition and bioactivity of essential oils of mentioned varieties. Presented results show that S. montana essential oil could be proposed as a valuable source of natural preservatives.
T2  - Lekovite sirovine
T1  - Bioactivity of essential oils from cultivated winter savory, sage and hyssop
IS  - 39
SP  - 11
EP  - 17
DO  - 10.5937/leksir1939011A
ER  - 

@article{
author = "Aćimović, Milica G. and Todosijević, Marina and Varga, Ana and Kiprovski, Biljana and Tešević, Vele and Čabarkapa, Ivana and Sikora, Vladimir",
year = "2019",
abstract = "Species of the Lamiaceae family have enjoyed a rich tradition of use for flavoring, food preservation, and medicinal purposes, due to their curative and preventive properties. Cultivated winter savory (Satureja montana L.), sage (Salvia officinalis L.) and hyssop (Hyssopus officinalis L.) are produced for seed, herb, and essential oil. Dominant compounds in S. montana essential oil were carvacrol (43.2%) and thymol (28.4%), while CIS-thujone (27.1%) and camphor (19.3%), followed by trans-thujone and 1,8-cineole were the major compounds in S. officinalis essential oil. As for H. officinalis essential oil, CIS-and trans-pinocamphone (41.1% and 20.5%, respectively) were the most abundant compounds, followed by b-pinene. S. montana essential oil exhibit the highest antimicrobial properties, as well as antioxidant capacity, compared to other tested essential oils. Furthermore, H. officinalis essential oils showed higher antioxidant activity than that of S. officinalis. The aim of this investigation was to determine the composition and bioactivity of essential oils of mentioned varieties. Presented results show that S. montana essential oil could be proposed as a valuable source of natural preservatives.",
journal = "Lekovite sirovine",
title = "Bioactivity of essential oils from cultivated winter savory, sage and hyssop",
number = "39",
pages = "11-17",
doi = "10.5937/leksir1939011A"
}

Aćimović, M. G., Todosijević, M., Varga, A., Kiprovski, B., Tešević, V., Čabarkapa, I.,& Sikora, V.. (2019). Bioactivity of essential oils from cultivated winter savory, sage and hyssop. in Lekovite sirovine(39), 11-17.
https://doi.org/10.5937/leksir1939011A

Aćimović MG, Todosijević M, Varga A, Kiprovski B, Tešević V, Čabarkapa I, Sikora V. Bioactivity of essential oils from cultivated winter savory, sage and hyssop. in Lekovite sirovine. 2019;(39):11-17.
doi:10.5937/leksir1939011A .

Aćimović, Milica G., Todosijević, Marina, Varga, Ana, Kiprovski, Biljana, Tešević, Vele, Čabarkapa, Ivana, Sikora, Vladimir, "Bioactivity of essential oils from cultivated winter savory, sage and hyssop" in Lekovite sirovine, no. 39 (2019):11-17,
https://doi.org/10.5937/leksir1939011A . .