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Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids
dc.creator | Joksović, Milan D. | |
dc.creator | Bogdanović, Gordana | |
dc.creator | Kojić, Vesna | |
dc.creator | Szecsenyi, Katalin Meszaros | |
dc.creator | Leovac, Vukadin M. | |
dc.creator | Jakimov, Dimitar | |
dc.creator | Trifunović, Snežana S. | |
dc.creator | Marković, Violeta | |
dc.creator | Joksović, Ljubinka | |
dc.date.accessioned | 2018-11-22T00:16:41Z | |
dc.date.available | 2018-11-22T00:16:41Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 0022-152X | |
dc.identifier.uri | https://cherry.chem.bg.ac.rs/handle/123456789/1097 | |
dc.description.abstract | New N-[(1,3-diphenylpyrazol-4-yl)methyl]alpha-amino acids (1a-i) have been synthesized and tested in vitro for their antiproliferative activity against human myelogenous leukemia K562, colon adenocarcinoma HT-29, cervix carcinoma HeLa, and normal fetal lung fibroblasts, MRC-5. Compounds derived from both phenylalanine enantiomer precursors appeared to be the most active against myelogenous leukemia K562 cell lines with a high cytotoxic potential. | en |
dc.publisher | Wiley-Blackwell, Malden | |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/142028/RS// | |
dc.relation | Provincial Secretariat for Science and Technological Development of Vojvodina | |
dc.rights | restrictedAccess | |
dc.source | Journal of Heterocyclic Chemistry | |
dc.title | Synthesis, Cytotoxic Activity, and Thermal Studies of Novel N-[(1,3-Diphenylpyrazol-4-yl)methyl] alpha-Amino Acids | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Јоксовиц, Љубинка; Сзецсенyи, Каталин Месзарос; Трифуновић, Снежана; Марковиц, Виолета; Леовац, Вукадин М.; Јоксовиц, Милан Д.; Јакимов, Димитар; Којиц, Весна; Богдановиц, Гордана; | |
dc.citation.volume | 47 | |
dc.citation.issue | 4 | |
dc.citation.spage | 850 | |
dc.citation.epage | 856 | |
dc.identifier.wos | 000280450700010 | |
dc.identifier.doi | 10.1002/jhet.400 | |
dc.citation.other | 47(4): 850-856 | |
dc.citation.rank | M23 | |
dc.type.version | publishedVersion | en |
dc.identifier.scopus | 2-s2.0-77954598700 |