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dc.creatorZdunić, Gordana
dc.creatorGođevac, Dejan
dc.creatorŠavikin, Katarina
dc.creatorNovaković, Miroslav M.
dc.creatorMilosavljević, Slobodan M.
dc.creatorPetrović, Silvana
dc.date.accessioned2018-11-22T00:18:00Z
dc.date.available2018-11-22T00:18:00Z
dc.date.issued2011
dc.identifier.issn1478-6419
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/1148
dc.description.abstractThe chemical composition and free radical scavenging properties of the MeOH extract of Hypericum richeri and its subsequent CHCl3, n-BuOH, EtOAc and aqueous extracts were investigated. Four quercetin-3-O-glycosides, three myricetin-3-O-glycosides, 3-O- and 5-O-caffeoylquinic acid, quercetin, I3,II8-biapigenin, pseudohypericin and hypericin were identified. The constituents of the extracts were quantified using HPLC-DAD (high-performance liquid chromatography-diode array detector). Isolation of the compounds from n-BuOH and EtOAc extracts was conducted by column chromatography. Antioxidant capacity of the extracts was evaluated by superoxide radical and ABTS root+ scavenging assays and inhibition of lipid peroxidation. The EtOAc extract of H. richeri was the most potent antioxidant in all experiments. Free radical scavenging compounds were identified by HPLC-DPPH root (high-performance liquid chromatography-2,2-diphenyl-1-picrylhydrazyl) post-column derivatisation method, where all phenolic compounds except I3,II8-biapigenin exhibited radical scavenging properties. This is the first report of the presence of myricetin-3-O-rutinoside, myricetin-3-O-galactoside, myricetin-3-O-glucoside, 5-O-caffeoylquinic acid and I3,II8-biapigenin in H. richeri.en
dc.publisherTaylor & Francis Ltd, Abingdon
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/20035/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/143012/RS//
dc.rightsrestrictedAccess
dc.sourceNatural Product Research
dc.subjectHypericum richerien
dc.subjectphenolicsen
dc.subjectHPLC-DADen
dc.subjecton-line HPLC-DPPHen
dc.subjectantioxidant capacityen
dc.titleIsolation and identification of phenolic compounds from Hypericum richeri Vill. and their antioxidant capacityen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСавикин, Катарина; Здуниц, Гордана; Годевац, Дејан; Новаковиц, Мирослав; Петровиц, Силвана; Милосављевиц, Слободан;
dc.citation.volume25
dc.citation.issue3
dc.citation.spage175
dc.citation.epage187
dc.identifier.wos000286894900001
dc.identifier.doi10.1080/14786410802401390
dc.citation.other25(3): 175-187
dc.citation.rankM23
dc.identifier.pmid19764002
dc.identifier.scopus2-s2.0-79551671472
dc.identifier.rcubKon_2148


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