NF-kappa B DNA binding activity of sesquiterpene lactones from Anthemis arvensis and Anthemis cotula
Vujisić, Ljubodrag V.
Klaas, Christoph A.
Milosavljević, Slobodan M.
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Previous investigations of Anthemis arvensis L. and Anthemis cotula L., species growing wild in Serbia, revealed linear sesquiterpene lactones (SLs) with unusual types of skeleton, named antheindurolides and anthecotuloides. The NF-B DNA binding activity of four of those SLs as well as from compounds representing structural parts of the SLs is reported in this article. The relationship between their structure and NF-B inhibition potency is briefly discussed.
Кључне речи:Anthemis / irregular linear sesquiterpene lactones / NF-B DNA binding activity
Извор:Natural Product Research, 2011, 25, 8, 800-805
- Taylor & Francis Ltd, Abingdon