Palladium(II) complexes with R(2)edda derived ligands. Part VI. O,O '-Diisopropyl ester of N,N '-1,2-ethanediylbis-L-leucine, dihydrochloride dihydrate and its palladium(II) complex: synthesis and characterization

Abstract

A new R(2)edda-type ester, O,O'-diisopropyl ester of N,N'-1,2-ethanediylbis-L-leucine, dihydrochloride dihydrate, [(S,S)-H(2)iPr(2)eddl]Cl-2 center dot 2H(2)O, 1, and its palladium(II) complex, dichlorido(O,O'-diisopropyl-N,N'-1,2-ethanediylbis-L-leucinate)palladium(II) hemihydrate, [PdCl2{(S,S)-iPr(2)eddl}]center dot 0.5H(2)O, 2, were synthesized and characterized by elemental analysis, and IR and NMR spectroscopy. As expected, the palladium(II) complex was found in two from three possible diastereoisomeric forms (R,R), (S,S) and (R,S) equivalent to (S,R).

Nov estar R2dda-tipa 0,0'-diizopropil estar N,N'-1,2-etandiilbis-L-leucina, dihidrohlorid dihidrat [(S,S)-H2iPr2eddl]Cl2-2H2O (1) i njegov kompleks paladijuma(II), dihlorido(0,0'-diizopropil-N,N'-1,2-etandiilbis-L-leucinat)paladijum(II)- -hemihidrat [PdCl2{(S,SHPr2eddl}]-0.5H2O (2) su sintetisani i okarakterisani uz pomoć elementalne analize, IR i NMR spektroskopije. Kalijum-tetrahloridopaladat(II), reagujući sa [(S,S)-H2iPr2eddl]Cl2-2H2O, očekivano daje paladijumov kompleks 2 u obliku dva od moguća tri dijastereoizomera, (R,R), (S,S) i (R,S) = (S,R), što je potvrđeno uz pomoć NMR spektroskopije, a u saglasnosti je sa ranije urađenim DFT proračunima. PR Projekat Ministarstva nauke Republike Srbije, br. 172035.