Platinum(IV) complexes with N-alkylphenothiazines: synthesis, characterization, and antibacterial activity
Само за регистроване кориснике
2013
Аутори
Poljarević, JelenaKrstić, Milena
Grgurić-Šipka, Sanja
Sovilj, Sofija P.
Mišić, Dušan R.
Sabo, Tibor
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Two new platinum(IV) complexes (1, trifluoperazinehydrochloride-aquapentachloridoplatinate(IV) and 2, chlorpromazine-chlorpromazinehydrochloridepentachloridoplatinate(IV)) were synthesized in the reaction of K-2[PtCl6] with trifluoperazine dihydrochloride (TF center dot 2HCl) or chlorpromazine hydrochloride (CP center dot HCl). The complexes were characterized by elemental analysis, molar conductivity measurement, and spectral (IR, H-1, C-13, 2D H-1-C-13 heteronuclear correlation spectra, Pt-195 NMR, and MS) methods. Outer-coordination sphere was proposed for 1; while in 2, the ligand was coordinated to the metal. The complexes exhibit antibacterial effect on strains of Bacillus subtilis, Bacillus cereus, Bacillus pumilus, and methicillin-resistant Staphylococci as Gram-positive bacteria and an Escherichia coli as Gram-negative bacteria, as well as the reference strains.
Кључне речи:
Platinum(IV) / N-alkylphenothiazines / Antibacterial activityИзвор:
Journal of Coordination Chemistry, 2013, 66, 21, 3760-3769Издавач:
- Taylor & Francis Ltd, Abingdon
Финансирање / пројекти:
- Дизајнирање, синтеза, карактеризација и процена практичне примене координационих и органометалних једињења (RS-MESTD-Basic Research (BR or ON)-172014)
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3513
DOI: 10.1080/00958972.2013.851788
ISSN: 0095-8972
WoS: 000327946400006
Scopus: 2-s2.0-84888176092
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Poljarević, Jelena AU - Krstić, Milena AU - Grgurić-Šipka, Sanja AU - Sovilj, Sofija P. AU - Mišić, Dušan R. AU - Sabo, Tibor PY - 2013 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1452 AB - Two new platinum(IV) complexes (1, trifluoperazinehydrochloride-aquapentachloridoplatinate(IV) and 2, chlorpromazine-chlorpromazinehydrochloridepentachloridoplatinate(IV)) were synthesized in the reaction of K-2[PtCl6] with trifluoperazine dihydrochloride (TF center dot 2HCl) or chlorpromazine hydrochloride (CP center dot HCl). The complexes were characterized by elemental analysis, molar conductivity measurement, and spectral (IR, H-1, C-13, 2D H-1-C-13 heteronuclear correlation spectra, Pt-195 NMR, and MS) methods. Outer-coordination sphere was proposed for 1; while in 2, the ligand was coordinated to the metal. The complexes exhibit antibacterial effect on strains of Bacillus subtilis, Bacillus cereus, Bacillus pumilus, and methicillin-resistant Staphylococci as Gram-positive bacteria and an Escherichia coli as Gram-negative bacteria, as well as the reference strains. PB - Taylor & Francis Ltd, Abingdon T2 - Journal of Coordination Chemistry T1 - Platinum(IV) complexes with N-alkylphenothiazines: synthesis, characterization, and antibacterial activity VL - 66 IS - 21 SP - 3760 EP - 3769 DO - 10.1080/00958972.2013.851788 ER -
@article{ author = "Poljarević, Jelena and Krstić, Milena and Grgurić-Šipka, Sanja and Sovilj, Sofija P. and Mišić, Dušan R. and Sabo, Tibor", year = "2013", abstract = "Two new platinum(IV) complexes (1, trifluoperazinehydrochloride-aquapentachloridoplatinate(IV) and 2, chlorpromazine-chlorpromazinehydrochloridepentachloridoplatinate(IV)) were synthesized in the reaction of K-2[PtCl6] with trifluoperazine dihydrochloride (TF center dot 2HCl) or chlorpromazine hydrochloride (CP center dot HCl). The complexes were characterized by elemental analysis, molar conductivity measurement, and spectral (IR, H-1, C-13, 2D H-1-C-13 heteronuclear correlation spectra, Pt-195 NMR, and MS) methods. Outer-coordination sphere was proposed for 1; while in 2, the ligand was coordinated to the metal. The complexes exhibit antibacterial effect on strains of Bacillus subtilis, Bacillus cereus, Bacillus pumilus, and methicillin-resistant Staphylococci as Gram-positive bacteria and an Escherichia coli as Gram-negative bacteria, as well as the reference strains.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Journal of Coordination Chemistry", title = "Platinum(IV) complexes with N-alkylphenothiazines: synthesis, characterization, and antibacterial activity", volume = "66", number = "21", pages = "3760-3769", doi = "10.1080/00958972.2013.851788" }
Poljarević, J., Krstić, M., Grgurić-Šipka, S., Sovilj, S. P., Mišić, D. R.,& Sabo, T.. (2013). Platinum(IV) complexes with N-alkylphenothiazines: synthesis, characterization, and antibacterial activity. in Journal of Coordination Chemistry Taylor & Francis Ltd, Abingdon., 66(21), 3760-3769. https://doi.org/10.1080/00958972.2013.851788
Poljarević J, Krstić M, Grgurić-Šipka S, Sovilj SP, Mišić DR, Sabo T. Platinum(IV) complexes with N-alkylphenothiazines: synthesis, characterization, and antibacterial activity. in Journal of Coordination Chemistry. 2013;66(21):3760-3769. doi:10.1080/00958972.2013.851788 .
Poljarević, Jelena, Krstić, Milena, Grgurić-Šipka, Sanja, Sovilj, Sofija P., Mišić, Dušan R., Sabo, Tibor, "Platinum(IV) complexes with N-alkylphenothiazines: synthesis, characterization, and antibacterial activity" in Journal of Coordination Chemistry, 66, no. 21 (2013):3760-3769, https://doi.org/10.1080/00958972.2013.851788 . .