Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor
Апстракт
In the present paper a glassy carbon electrode was successfully applied for the sensitive and selective determination of the indole alkaloid reserpine by differential pulse voltammetry (DPV). The electrochemical behavior of reserpine was investigated using cyclic voltammetry and best conditions for its quantification were examined by differential pulse voltammetry. Cyclic voltammetry has shown that the oxidation process is irreversible over the pH range 1 - 12 and that the electrode process is mainly diffusion controlled. The proposed procedure has wide linear concentration range for determination of reserpine by DPV from 2 mu M to 75 mu M with a detection limit 0.6 mu M. The sensor in combination with optimized electrochemical parameters was successfully applied for the determination of reserpine in model human urine with good recovery.
Кључне речи:
Reserpine / glassy carbon electrode / differential pulse voltammetry / human urine sampleИзвор:
International Journal of Electrochemical Science, 2015, 10, 2, 1469-1477Издавач:
- Esg, Belgrade
Финансирање / пројекти:
- Примена унапређених оксидационих процеса и наноструктурисаних оксидних материјала за уклањање загађивача из животне средине, развој и оптимизација инструменталних техника за праћење ефикасности (RS-MESTD-Basic Research (BR or ON)-172030)
- Grant Agency of the Slovak Republic [1/0051/13]
Колекције
Институција/група
Inovacioni centar / Innovation CentreTY - JOUR AU - Stanković, Dalibor AU - Mehmeti, Eda AU - Šovrc, Ľubomír AU - Kalcher, Kurt PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1642 AB - In the present paper a glassy carbon electrode was successfully applied for the sensitive and selective determination of the indole alkaloid reserpine by differential pulse voltammetry (DPV). The electrochemical behavior of reserpine was investigated using cyclic voltammetry and best conditions for its quantification were examined by differential pulse voltammetry. Cyclic voltammetry has shown that the oxidation process is irreversible over the pH range 1 - 12 and that the electrode process is mainly diffusion controlled. The proposed procedure has wide linear concentration range for determination of reserpine by DPV from 2 mu M to 75 mu M with a detection limit 0.6 mu M. The sensor in combination with optimized electrochemical parameters was successfully applied for the determination of reserpine in model human urine with good recovery. PB - Esg, Belgrade T2 - International Journal of Electrochemical Science T1 - Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor VL - 10 IS - 2 SP - 1469 EP - 1477 UR - https://hdl.handle.net/21.15107/rcub_cherry_1642 ER -
@article{ author = "Stanković, Dalibor and Mehmeti, Eda and Šovrc, Ľubomír and Kalcher, Kurt", year = "2015", abstract = "In the present paper a glassy carbon electrode was successfully applied for the sensitive and selective determination of the indole alkaloid reserpine by differential pulse voltammetry (DPV). The electrochemical behavior of reserpine was investigated using cyclic voltammetry and best conditions for its quantification were examined by differential pulse voltammetry. Cyclic voltammetry has shown that the oxidation process is irreversible over the pH range 1 - 12 and that the electrode process is mainly diffusion controlled. The proposed procedure has wide linear concentration range for determination of reserpine by DPV from 2 mu M to 75 mu M with a detection limit 0.6 mu M. The sensor in combination with optimized electrochemical parameters was successfully applied for the determination of reserpine in model human urine with good recovery.", publisher = "Esg, Belgrade", journal = "International Journal of Electrochemical Science", title = "Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor", volume = "10", number = "2", pages = "1469-1477", url = "https://hdl.handle.net/21.15107/rcub_cherry_1642" }
Stanković, D., Mehmeti, E., Šovrc, Ľ.,& Kalcher, K.. (2015). Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor. in International Journal of Electrochemical Science Esg, Belgrade., 10(2), 1469-1477. https://hdl.handle.net/21.15107/rcub_cherry_1642
Stanković D, Mehmeti E, Šovrc Ľ, Kalcher K. Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor. in International Journal of Electrochemical Science. 2015;10(2):1469-1477. https://hdl.handle.net/21.15107/rcub_cherry_1642 .
Stanković, Dalibor, Mehmeti, Eda, Šovrc, Ľubomír, Kalcher, Kurt, "Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor" in International Journal of Electrochemical Science, 10, no. 2 (2015):1469-1477, https://hdl.handle.net/21.15107/rcub_cherry_1642 .