Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor
Apstrakt
In the present paper a glassy carbon electrode was successfully applied for the sensitive and selective determination of the indole alkaloid reserpine by differential pulse voltammetry (DPV). The electrochemical behavior of reserpine was investigated using cyclic voltammetry and best conditions for its quantification were examined by differential pulse voltammetry. Cyclic voltammetry has shown that the oxidation process is irreversible over the pH range 1 - 12 and that the electrode process is mainly diffusion controlled. The proposed procedure has wide linear concentration range for determination of reserpine by DPV from 2 mu M to 75 mu M with a detection limit 0.6 mu M. The sensor in combination with optimized electrochemical parameters was successfully applied for the determination of reserpine in model human urine with good recovery.
Ključne reči:
Reserpine / glassy carbon electrode / differential pulse voltammetry / human urine sampleIzvor:
International Journal of Electrochemical Science, 2015, 10, 2, 1469-1477Izdavač:
- Esg, Belgrade
Finansiranje / projekti:
- Primena unapređenih oksidacionih procesa i nanostrukturisanih oksidnih materijala za uklanjanje zagađivača iz životne sredine, razvoj i optimizacija instrumentalnih tehnika za praćenje efikasnosti (RS-MESTD-Basic Research (BR or ON)-172030)
- Grant Agency of the Slovak Republic [1/0051/13]
Kolekcije
Institucija/grupa
Inovacioni centar / Innovation CentreTY - JOUR AU - Stanković, Dalibor AU - Mehmeti, Eda AU - Šovrc, Ľubomír AU - Kalcher, Kurt PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1642 AB - In the present paper a glassy carbon electrode was successfully applied for the sensitive and selective determination of the indole alkaloid reserpine by differential pulse voltammetry (DPV). The electrochemical behavior of reserpine was investigated using cyclic voltammetry and best conditions for its quantification were examined by differential pulse voltammetry. Cyclic voltammetry has shown that the oxidation process is irreversible over the pH range 1 - 12 and that the electrode process is mainly diffusion controlled. The proposed procedure has wide linear concentration range for determination of reserpine by DPV from 2 mu M to 75 mu M with a detection limit 0.6 mu M. The sensor in combination with optimized electrochemical parameters was successfully applied for the determination of reserpine in model human urine with good recovery. PB - Esg, Belgrade T2 - International Journal of Electrochemical Science T1 - Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor VL - 10 IS - 2 SP - 1469 EP - 1477 UR - https://hdl.handle.net/21.15107/rcub_cherry_1642 ER -
@article{ author = "Stanković, Dalibor and Mehmeti, Eda and Šovrc, Ľubomír and Kalcher, Kurt", year = "2015", abstract = "In the present paper a glassy carbon electrode was successfully applied for the sensitive and selective determination of the indole alkaloid reserpine by differential pulse voltammetry (DPV). The electrochemical behavior of reserpine was investigated using cyclic voltammetry and best conditions for its quantification were examined by differential pulse voltammetry. Cyclic voltammetry has shown that the oxidation process is irreversible over the pH range 1 - 12 and that the electrode process is mainly diffusion controlled. The proposed procedure has wide linear concentration range for determination of reserpine by DPV from 2 mu M to 75 mu M with a detection limit 0.6 mu M. The sensor in combination with optimized electrochemical parameters was successfully applied for the determination of reserpine in model human urine with good recovery.", publisher = "Esg, Belgrade", journal = "International Journal of Electrochemical Science", title = "Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor", volume = "10", number = "2", pages = "1469-1477", url = "https://hdl.handle.net/21.15107/rcub_cherry_1642" }
Stanković, D., Mehmeti, E., Šovrc, Ľ.,& Kalcher, K.. (2015). Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor. in International Journal of Electrochemical Science Esg, Belgrade., 10(2), 1469-1477. https://hdl.handle.net/21.15107/rcub_cherry_1642
Stanković D, Mehmeti E, Šovrc Ľ, Kalcher K. Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor. in International Journal of Electrochemical Science. 2015;10(2):1469-1477. https://hdl.handle.net/21.15107/rcub_cherry_1642 .
Stanković, Dalibor, Mehmeti, Eda, Šovrc, Ľubomír, Kalcher, Kurt, "Sensitive Determination of the Indole Alkaloid Reserpine Using a Glassy Carbon Based Electrochemical Sensor" in International Journal of Electrochemical Science, 10, no. 2 (2015):1469-1477, https://hdl.handle.net/21.15107/rcub_cherry_1642 .