Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains
AuthorsRadovanovic, Aleksandra N.
Radovanovic, Blaga C.
Article (Published version)
MetadataShow full item record
Purpose: The aim of this study was to assess potential antimicrobial effectiveness of selected red wines from Balkan region, made from autochthonic Vranac V. vinifera L. grape variety. Methods: The antimicrobial activity of Vranac wines against Gram-positive: C. perfringens, B. subtillis, S. aureus, L. inocua, S. Lutea, and M. flavus and Gram-negative: E. coli, P. aeruginosa, S. enteritidis, S. sonnei, K. pneumonia and P. vulgaris bacteria stains were studied using the agar well diffusion and micro-well dilution methods. The concentrations of the wine phenolic compounds: gallic acid, caffeic acid, (+)-catechin, resveratrol, quercetin, quercetin-3-glucoside and malvidin-3-glucoside were determined using HPLC analysis. Results: There was excellent correlation between the contents of gallic acid, caffeic acid, resveratrol, quercetin, quercetin-3-glucoside and malvidine-3-glucoside and the antimicrobial activity of the wines against Gram-positive - C. perfringens and M. flavus (from 0.936 ...to 0.999) and against Gram-negative bacteria stains - E. coli, P. aeruginosa, S. enteritidis, S. sonnei and P. vulgaris (from 0.904 to 0.999). Furthermore, the content of (+)-catechin has good correlation with the antimicrobial activity of the wines only against L. inocua and P. vulgaris with correlation coefficient of 0.996 and 0.999, respectively. All selected wine phenolic compounds, however, did not show correlation with antimicrobial activity against K. pneumonia strain. Conclusion: The antimicrobial activity of selected Vranac wines indicates that some of the wine's phenolic constituents have the potential to inhibit the growth of certain bacterial strains.
Keywords:Red wine / Antimicrobial activity / Bacterial strains / Phenolic compounds
Source:Tropical Journal of Pharmaceutical Research, 2014, 13, 5, 819-824
- Pharmacotherapy Group, Benin City
- Plants and synthetic bioactive products of new generation (RS-34012)
- Development of new technology for production of red wine and diatery supplements reach with polyphenols with cardioprotective effects (RS-31020)
- Geochemical investigations of sedimentary rocks - fossil fuels and environmental pollutants (RS-176006)
- Reinforcement of the WBC research capacities for food quality characterization (EU-204756)
- Europe Union [FP7-Regpot-2007-3-01]