Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains
Apstrakt
Purpose: The aim of this study was to assess potential antimicrobial effectiveness of selected red wines from Balkan region, made from autochthonic Vranac V. vinifera L. grape variety. Methods: The antimicrobial activity of Vranac wines against Gram-positive: C. perfringens, B. subtillis, S. aureus, L. inocua, S. Lutea, and M. flavus and Gram-negative: E. coli, P. aeruginosa, S. enteritidis, S. sonnei, K. pneumonia and P. vulgaris bacteria stains were studied using the agar well diffusion and micro-well dilution methods. The concentrations of the wine phenolic compounds: gallic acid, caffeic acid, (+)-catechin, resveratrol, quercetin, quercetin-3-glucoside and malvidin-3-glucoside were determined using HPLC analysis. Results: There was excellent correlation between the contents of gallic acid, caffeic acid, resveratrol, quercetin, quercetin-3-glucoside and malvidine-3-glucoside and the antimicrobial activity of the wines against Gram-positive - C. perfringens and M. flavus (from 0.936 ...to 0.999) and against Gram-negative bacteria stains - E. coli, P. aeruginosa, S. enteritidis, S. sonnei and P. vulgaris (from 0.904 to 0.999). Furthermore, the content of (+)-catechin has good correlation with the antimicrobial activity of the wines only against L. inocua and P. vulgaris with correlation coefficient of 0.996 and 0.999, respectively. All selected wine phenolic compounds, however, did not show correlation with antimicrobial activity against K. pneumonia strain. Conclusion: The antimicrobial activity of selected Vranac wines indicates that some of the wine's phenolic constituents have the potential to inhibit the growth of certain bacterial strains.
Ključne reči:
Red wine / Antimicrobial activity / Bacterial strains / Phenolic compoundsIzvor:
Tropical Journal of Pharmaceutical Research, 2014, 13, 5, 819-824Izdavač:
- Pharmacotherapy Group, Benin City
Finansiranje / projekti:
- Biljni i sintetički bioaktivni proizvodi novije generacije (RS-MESTD-Technological Development (TD or TR)-34012)
- Razvoj tehnologije proizvodnje crvenog vina i dijetetskih proizvoda iz vina bogatih biološki aktivnim polifenolima sa kardioprotektivnim dejstvima (RS-MESTD-Technological Development (TD or TR)-31020)
- Geohemijska ispitivanja sedimentnih stena - fosilna goriva i zagađivači životne sredine (RS-MESTD-Basic Research (BR or ON)-176006)
- Reinforcement of the WBC research capacities for food quality characterization (EU-FP7-204756)
- Europe Union [FP7-Regpot-2007-3-01]
DOI: 10.4314/tjpr.v13i5.24
ISSN: 1596-5996
WoS: 000339625100024
Scopus: 2-s2.0-84901914803
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Radovanović, Aleksandra AU - Jovančićević, Branimir AU - Radovanović, Blaga AU - Mihajilov-Krstev, Tatjana PY - 2014 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1822 AB - Purpose: The aim of this study was to assess potential antimicrobial effectiveness of selected red wines from Balkan region, made from autochthonic Vranac V. vinifera L. grape variety. Methods: The antimicrobial activity of Vranac wines against Gram-positive: C. perfringens, B. subtillis, S. aureus, L. inocua, S. Lutea, and M. flavus and Gram-negative: E. coli, P. aeruginosa, S. enteritidis, S. sonnei, K. pneumonia and P. vulgaris bacteria stains were studied using the agar well diffusion and micro-well dilution methods. The concentrations of the wine phenolic compounds: gallic acid, caffeic acid, (+)-catechin, resveratrol, quercetin, quercetin-3-glucoside and malvidin-3-glucoside were determined using HPLC analysis. Results: There was excellent correlation between the contents of gallic acid, caffeic acid, resveratrol, quercetin, quercetin-3-glucoside and malvidine-3-glucoside and the antimicrobial activity of the wines against Gram-positive - C. perfringens and M. flavus (from 0.936 to 0.999) and against Gram-negative bacteria stains - E. coli, P. aeruginosa, S. enteritidis, S. sonnei and P. vulgaris (from 0.904 to 0.999). Furthermore, the content of (+)-catechin has good correlation with the antimicrobial activity of the wines only against L. inocua and P. vulgaris with correlation coefficient of 0.996 and 0.999, respectively. All selected wine phenolic compounds, however, did not show correlation with antimicrobial activity against K. pneumonia strain. Conclusion: The antimicrobial activity of selected Vranac wines indicates that some of the wine's phenolic constituents have the potential to inhibit the growth of certain bacterial strains. PB - Pharmacotherapy Group, Benin City T2 - Tropical Journal of Pharmaceutical Research T1 - Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains VL - 13 IS - 5 SP - 819 EP - 824 DO - 10.4314/tjpr.v13i5.24 ER -
@article{ author = "Radovanović, Aleksandra and Jovančićević, Branimir and Radovanović, Blaga and Mihajilov-Krstev, Tatjana", year = "2014", abstract = "Purpose: The aim of this study was to assess potential antimicrobial effectiveness of selected red wines from Balkan region, made from autochthonic Vranac V. vinifera L. grape variety. Methods: The antimicrobial activity of Vranac wines against Gram-positive: C. perfringens, B. subtillis, S. aureus, L. inocua, S. Lutea, and M. flavus and Gram-negative: E. coli, P. aeruginosa, S. enteritidis, S. sonnei, K. pneumonia and P. vulgaris bacteria stains were studied using the agar well diffusion and micro-well dilution methods. The concentrations of the wine phenolic compounds: gallic acid, caffeic acid, (+)-catechin, resveratrol, quercetin, quercetin-3-glucoside and malvidin-3-glucoside were determined using HPLC analysis. Results: There was excellent correlation between the contents of gallic acid, caffeic acid, resveratrol, quercetin, quercetin-3-glucoside and malvidine-3-glucoside and the antimicrobial activity of the wines against Gram-positive - C. perfringens and M. flavus (from 0.936 to 0.999) and against Gram-negative bacteria stains - E. coli, P. aeruginosa, S. enteritidis, S. sonnei and P. vulgaris (from 0.904 to 0.999). Furthermore, the content of (+)-catechin has good correlation with the antimicrobial activity of the wines only against L. inocua and P. vulgaris with correlation coefficient of 0.996 and 0.999, respectively. All selected wine phenolic compounds, however, did not show correlation with antimicrobial activity against K. pneumonia strain. Conclusion: The antimicrobial activity of selected Vranac wines indicates that some of the wine's phenolic constituents have the potential to inhibit the growth of certain bacterial strains.", publisher = "Pharmacotherapy Group, Benin City", journal = "Tropical Journal of Pharmaceutical Research", title = "Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains", volume = "13", number = "5", pages = "819-824", doi = "10.4314/tjpr.v13i5.24" }
Radovanović, A., Jovančićević, B., Radovanović, B.,& Mihajilov-Krstev, T.. (2014). Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains. in Tropical Journal of Pharmaceutical Research Pharmacotherapy Group, Benin City., 13(5), 819-824. https://doi.org/10.4314/tjpr.v13i5.24
Radovanović A, Jovančićević B, Radovanović B, Mihajilov-Krstev T. Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains. in Tropical Journal of Pharmaceutical Research. 2014;13(5):819-824. doi:10.4314/tjpr.v13i5.24 .
Radovanović, Aleksandra, Jovančićević, Branimir, Radovanović, Blaga, Mihajilov-Krstev, Tatjana, "Antimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strains" in Tropical Journal of Pharmaceutical Research, 13, no. 5 (2014):819-824, https://doi.org/10.4314/tjpr.v13i5.24 . .