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dc.creatorRadovanovic, Aleksandra N.
dc.creatorJovančićević, Branimir
dc.creatorRadovanovic, Blaga C.
dc.creatorMihajilov-Krstev, Tatjana
dc.date.accessioned2018-11-22T00:28:42Z
dc.date.available2018-11-22T00:28:42Z
dc.date.issued2014
dc.identifier.issn1596-5996
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/1822
dc.description.abstractPurpose: The aim of this study was to assess potential antimicrobial effectiveness of selected red wines from Balkan region, made from autochthonic Vranac V. vinifera L. grape variety. Methods: The antimicrobial activity of Vranac wines against Gram-positive: C. perfringens, B. subtillis, S. aureus, L. inocua, S. Lutea, and M. flavus and Gram-negative: E. coli, P. aeruginosa, S. enteritidis, S. sonnei, K. pneumonia and P. vulgaris bacteria stains were studied using the agar well diffusion and micro-well dilution methods. The concentrations of the wine phenolic compounds: gallic acid, caffeic acid, (+)-catechin, resveratrol, quercetin, quercetin-3-glucoside and malvidin-3-glucoside were determined using HPLC analysis. Results: There was excellent correlation between the contents of gallic acid, caffeic acid, resveratrol, quercetin, quercetin-3-glucoside and malvidine-3-glucoside and the antimicrobial activity of the wines against Gram-positive - C. perfringens and M. flavus (from 0.936 to 0.999) and against Gram-negative bacteria stains - E. coli, P. aeruginosa, S. enteritidis, S. sonnei and P. vulgaris (from 0.904 to 0.999). Furthermore, the content of (+)-catechin has good correlation with the antimicrobial activity of the wines only against L. inocua and P. vulgaris with correlation coefficient of 0.996 and 0.999, respectively. All selected wine phenolic compounds, however, did not show correlation with antimicrobial activity against K. pneumonia strain. Conclusion: The antimicrobial activity of selected Vranac wines indicates that some of the wine's phenolic constituents have the potential to inhibit the growth of certain bacterial strains.en
dc.publisherPharmacotherapy Group, Benin City
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34012/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31020/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/176006/RS//
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/204756/EU//
dc.relationEurope Union [FP7-Regpot-2007-3-01]
dc.rightsopenAccess
dc.sourceTropical Journal of Pharmaceutical Research
dc.subjectRed wineen
dc.subjectAntimicrobial activityen
dc.subjectBacterial strainsen
dc.subjectPhenolic compoundsen
dc.titleAntimicrobial Effectiveness of Selected Vranac Wines Against Six Gram-Positive and Six Gram-Negative Bacterial Strainsen
dc.typearticle
dc.rights.licenseBY
dcterms.abstractРадовановиц, Блага Ц.; Радовановиц, Aлександра Н.; Јованчићевић, Бранимир; Михајилов-Крстев, Татјана;
dc.citation.volume13
dc.citation.issue5
dc.citation.spage819
dc.citation.epage824
dc.identifier.wos000339625100024
dc.identifier.doi10.4314/tjpr.v13i5.24
dc.citation.other13(5): 819-824
dc.citation.rankM23
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-84901914803
dc.identifier.rcubKon_2705


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