Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases
Само за регистроване кориснике
2015
Аутори
Perušković, Danica S.Daric, Branka
Blagus, Anita
Stevanović, Nikola R.
Pavlović, Aleksandra V.
Lolić, Aleksandar
Baošić, Rada
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed.
Кључне речи:
Schiff bases / RP-TLC / PCA / Lipophilicity / Molecular modeling / BioinformaticsИзвор:
Monatshefte Fur Chemie, 2015, 146, 1, 1-6Издавач:
- Springer Wien, Wien
Финансирање / пројекти:
- Корелација структуре и особина природних и синтетичких молекула и њихових комплекса са металима (RS-172017)
DOI: 10.1007/s00706-014-1313-7
ISSN: 0026-9247
WoS: 000347161300001
Scopus: 2-s2.0-84921937430
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Perušković, Danica S. AU - Daric, Branka AU - Blagus, Anita AU - Stevanović, Nikola R. AU - Pavlović, Aleksandra V. AU - Lolić, Aleksandar AU - Baošić, Rada PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1894 AB - The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed. PB - Springer Wien, Wien T2 - Monatshefte Fur Chemie T1 - Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases VL - 146 IS - 1 SP - 1 EP - 6 DO - 10.1007/s00706-014-1313-7 ER -
@article{ author = "Perušković, Danica S. and Daric, Branka and Blagus, Anita and Stevanović, Nikola R. and Pavlović, Aleksandra V. and Lolić, Aleksandar and Baošić, Rada", year = "2015", abstract = "The lipophilic character of polydentate Schiff bases was investigated by reversed-phase thin-layer chromatography. In order to determine retention parameter as a measure of the lipophilicity of the tested compounds, three different binary solvent systems, composed of water and organic modifier (methanol, acetonitrile, and tetrahydrofuran), were used. Lipophilicity parameters together with 2D molecular descriptors were subjected to the multivariate statistical analysis. Principal component analysis was employed to reveal the most influential factors governing the lipophilicity of the investigated compounds. Finally, the influence of organic modifier on determination of lipophilicity parameters was discussed.", publisher = "Springer Wien, Wien", journal = "Monatshefte Fur Chemie", title = "Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases", volume = "146", number = "1", pages = "1-6", doi = "10.1007/s00706-014-1313-7" }
Perušković, D. S., Daric, B., Blagus, A., Stevanović, N. R., Pavlović, A. V., Lolić, A.,& Baošić, R.. (2015). Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases. in Monatshefte Fur Chemie Springer Wien, Wien., 146(1), 1-6. https://doi.org/10.1007/s00706-014-1313-7
Perušković DS, Daric B, Blagus A, Stevanović NR, Pavlović AV, Lolić A, Baošić R. Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases. in Monatshefte Fur Chemie. 2015;146(1):1-6. doi:10.1007/s00706-014-1313-7 .
Perušković, Danica S., Daric, Branka, Blagus, Anita, Stevanović, Nikola R., Pavlović, Aleksandra V., Lolić, Aleksandar, Baošić, Rada, "Influence of organic modifiers on RP-TLC determination of lipophilicity of some polydentate Schiff bases" in Monatshefte Fur Chemie, 146, no. 1 (2015):1-6, https://doi.org/10.1007/s00706-014-1313-7 . .