The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid
2018
Autori
Cinková, KristínaKianicková, Kristína
Stanković, Dalibor
Vojs, Marian
Marton, Marian
Šovrc, Ľubomír
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applicatio...ns in uric acid sensing within clinical, pharmaceutical and environmental analysis.
Izvor:
Analytical Methods, 2018, 10, 9, 991-996Izdavač:
- Royal Soc Chemistry, Cambridge
Finansiranje / projekti:
- Primena unapređenih oksidacionih procesa i nanostrukturisanih oksidnih materijala za uklanjanje zagađivača iz životne sredine, razvoj i optimizacija instrumentalnih tehnika za praćenje efikasnosti (RS-MESTD-Basic Research (BR or ON)-172030)
- Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials (EU-FP7-621375)
- Grant scheme for Support of Excellent Teams of Young Researchers
- Grant Agency of the Slovak Republic [1/0489/16, 1/0887/16, 1/0558/17]
- Slovak Research and Development Agency [APVV-16-0124]
DOI: 10.1039/c7ay02720f
ISSN: 1759-9660
WoS: 000426696100009
Scopus: 2-s2.0-85042884267
Kolekcije
Institucija/grupa
Inovacioni centar / Innovation CentreTY - JOUR AU - Cinková, Kristína AU - Kianicková, Kristína AU - Stanković, Dalibor AU - Vojs, Marian AU - Marton, Marian AU - Šovrc, Ľubomír PY - 2018 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2102 AB - In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applications in uric acid sensing within clinical, pharmaceutical and environmental analysis. PB - Royal Soc Chemistry, Cambridge T2 - Analytical Methods T1 - The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid VL - 10 IS - 9 SP - 991 EP - 996 DO - 10.1039/c7ay02720f ER -
@article{ author = "Cinková, Kristína and Kianicková, Kristína and Stanković, Dalibor and Vojs, Marian and Marton, Marian and Šovrc, Ľubomír", year = "2018", abstract = "In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0-2000 ppm). The cyclic voltammetric study showed one irreversible oxidation peak at +(1.1-1.25) V (vs. Ag/AgCl/3 M KCl) in the presence of Britton-Robinson buffer (pH 2.25) depending on the boron content. Employing differential pulse voltammetry using the 2000 ppm boron-doped diamond electrode the acquired analytical parameters were as follows: a limit of detection of 7.7 M, a limit of quantification of 26 M and intra-day repeatability (relative standard deviation of 2.9% for n = 15). After performing an interference study, the method was applied to the determination of uric acid in biological samples (human urine). The uric acid concentrations determined in the urine samples were compared with the reference values stated in the literature. The proposed methodology using boron-doped diamond electrodes could find applications in uric acid sensing within clinical, pharmaceutical and environmental analysis.", publisher = "Royal Soc Chemistry, Cambridge", journal = "Analytical Methods", title = "The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid", volume = "10", number = "9", pages = "991-996", doi = "10.1039/c7ay02720f" }
Cinková, K., Kianicková, K., Stanković, D., Vojs, M., Marton, M.,& Šovrc, Ľ.. (2018). The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid. in Analytical Methods Royal Soc Chemistry, Cambridge., 10(9), 991-996. https://doi.org/10.1039/c7ay02720f
Cinková K, Kianicková K, Stanković D, Vojs M, Marton M, Šovrc Ľ. The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid. in Analytical Methods. 2018;10(9):991-996. doi:10.1039/c7ay02720f .
Cinková, Kristína, Kianicková, Kristína, Stanković, Dalibor, Vojs, Marian, Marton, Marian, Šovrc, Ľubomír, "The doping level of boron-doped diamond electrodes affects the voltammetric sensing ofuric acid" in Analytical Methods, 10, no. 9 (2018):991-996, https://doi.org/10.1039/c7ay02720f . .