Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex
Само за регистроване кориснике
2016
Аутори
Prokić, Marko D.Borković-Mitić, Slavica S.
Krizmanić, Imre I.
Mutić, Jelena
Trifković, Jelena
Gavrić, Jelena P.
Despotović, Svetlana G.
Gavrilović, Branka R.
Radovanović, Tijana B.
Pavlović, Slađan Z.
Saičić, Zorica S.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Metals are involved in the formation of reactive oxygen species and can induce oxidative stress. The aim of this study was to assess the effects of several metals on oxidative stress in the skin and muscle of the Pelophylax esculentus "complex" frogs (parental species Pelophylax ridibundus, Pelophylax lessonae, and their hybrid Pelophylax esculentus) that inhabit the wetland Obedska Bara in Serbia, and the potential use of these species as bioindicator organisms in biomonitoring studies. The biomarkers of oxidative stress (SOD, CAT, GSH-Px, GR, GST activities and GSH, SH concentrations) and cholinesterase activity were investigated. The concentrations of nine metals (Fe, Cu, Zn, As, Cd, Cr, Hg, Ni, and Pb) were measured in the water and tissues. Correlations were established between metals and biomarkers in the tissues. The results of metal accumulation distinguished the skin of P. lessonae and muscle of P. ridibundus from other P. esculentus complex species. The oxidative stress bioma...rkers observed in P. ridibundus and P. esculentus had greater similarity than in P. lessonae. The P. lessonae displayed the highest number of correlations between biomarkers and metals. The results of tissue responses revealed that skin was more susceptible to metal-induced oxidative stress, with only exception of As. In the light of these findings, we can suggest the use of P. esculentus complex species as a biomonitoring species in studies of metal accumulation and metal-induced oxidative stress, but with special emphasis on P. lessonae.
Кључне речи:
Antioxidative defense system / Bioaccumulation / Frogs / Metals / Oxidative stress / Pelophylax esculentus complexИзвор:
Ecotoxicology, 2016, 25, 8, 1531-1542Издавач:
- Springer, Dordrecht
Финансирање / пројекти:
- Молекуларно физиолошки биомониторинг аеробних организама заснован на одређивању биохемијских биомаркера оксидационог стреса (RS-MESTD-Basic Research (BR or ON)-173041)
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3391
DOI: 10.1007/s10646-016-1707-x
ISSN: 0963-9292
PubMed: 27629268
WoS: 000386710800008
Scopus: 2-s2.0-84988378039
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Prokić, Marko D. AU - Borković-Mitić, Slavica S. AU - Krizmanić, Imre I. AU - Mutić, Jelena AU - Trifković, Jelena AU - Gavrić, Jelena P. AU - Despotović, Svetlana G. AU - Gavrilović, Branka R. AU - Radovanović, Tijana B. AU - Pavlović, Slađan Z. AU - Saičić, Zorica S. PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2340 AB - Metals are involved in the formation of reactive oxygen species and can induce oxidative stress. The aim of this study was to assess the effects of several metals on oxidative stress in the skin and muscle of the Pelophylax esculentus "complex" frogs (parental species Pelophylax ridibundus, Pelophylax lessonae, and their hybrid Pelophylax esculentus) that inhabit the wetland Obedska Bara in Serbia, and the potential use of these species as bioindicator organisms in biomonitoring studies. The biomarkers of oxidative stress (SOD, CAT, GSH-Px, GR, GST activities and GSH, SH concentrations) and cholinesterase activity were investigated. The concentrations of nine metals (Fe, Cu, Zn, As, Cd, Cr, Hg, Ni, and Pb) were measured in the water and tissues. Correlations were established between metals and biomarkers in the tissues. The results of metal accumulation distinguished the skin of P. lessonae and muscle of P. ridibundus from other P. esculentus complex species. The oxidative stress biomarkers observed in P. ridibundus and P. esculentus had greater similarity than in P. lessonae. The P. lessonae displayed the highest number of correlations between biomarkers and metals. The results of tissue responses revealed that skin was more susceptible to metal-induced oxidative stress, with only exception of As. In the light of these findings, we can suggest the use of P. esculentus complex species as a biomonitoring species in studies of metal accumulation and metal-induced oxidative stress, but with special emphasis on P. lessonae. PB - Springer, Dordrecht T2 - Ecotoxicology T1 - Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex VL - 25 IS - 8 SP - 1531 EP - 1542 DO - 10.1007/s10646-016-1707-x ER -
@article{ author = "Prokić, Marko D. and Borković-Mitić, Slavica S. and Krizmanić, Imre I. and Mutić, Jelena and Trifković, Jelena and Gavrić, Jelena P. and Despotović, Svetlana G. and Gavrilović, Branka R. and Radovanović, Tijana B. and Pavlović, Slađan Z. and Saičić, Zorica S.", year = "2016", abstract = "Metals are involved in the formation of reactive oxygen species and can induce oxidative stress. The aim of this study was to assess the effects of several metals on oxidative stress in the skin and muscle of the Pelophylax esculentus "complex" frogs (parental species Pelophylax ridibundus, Pelophylax lessonae, and their hybrid Pelophylax esculentus) that inhabit the wetland Obedska Bara in Serbia, and the potential use of these species as bioindicator organisms in biomonitoring studies. The biomarkers of oxidative stress (SOD, CAT, GSH-Px, GR, GST activities and GSH, SH concentrations) and cholinesterase activity were investigated. The concentrations of nine metals (Fe, Cu, Zn, As, Cd, Cr, Hg, Ni, and Pb) were measured in the water and tissues. Correlations were established between metals and biomarkers in the tissues. The results of metal accumulation distinguished the skin of P. lessonae and muscle of P. ridibundus from other P. esculentus complex species. The oxidative stress biomarkers observed in P. ridibundus and P. esculentus had greater similarity than in P. lessonae. The P. lessonae displayed the highest number of correlations between biomarkers and metals. The results of tissue responses revealed that skin was more susceptible to metal-induced oxidative stress, with only exception of As. In the light of these findings, we can suggest the use of P. esculentus complex species as a biomonitoring species in studies of metal accumulation and metal-induced oxidative stress, but with special emphasis on P. lessonae.", publisher = "Springer, Dordrecht", journal = "Ecotoxicology", title = "Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex", volume = "25", number = "8", pages = "1531-1542", doi = "10.1007/s10646-016-1707-x" }
Prokić, M. D., Borković-Mitić, S. S., Krizmanić, I. I., Mutić, J., Trifković, J., Gavrić, J. P., Despotović, S. G., Gavrilović, B. R., Radovanović, T. B., Pavlović, S. Z.,& Saičić, Z. S.. (2016). Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex. in Ecotoxicology Springer, Dordrecht., 25(8), 1531-1542. https://doi.org/10.1007/s10646-016-1707-x
Prokić MD, Borković-Mitić SS, Krizmanić II, Mutić J, Trifković J, Gavrić JP, Despotović SG, Gavrilović BR, Radovanović TB, Pavlović SZ, Saičić ZS. Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex. in Ecotoxicology. 2016;25(8):1531-1542. doi:10.1007/s10646-016-1707-x .
Prokić, Marko D., Borković-Mitić, Slavica S., Krizmanić, Imre I., Mutić, Jelena, Trifković, Jelena, Gavrić, Jelena P., Despotović, Svetlana G., Gavrilović, Branka R., Radovanović, Tijana B., Pavlović, Slađan Z., Saičić, Zorica S., "Bioaccumulation and effects of metals on oxidative stress and neurotoxicity parameters in the frogs from the Pelophylax esculentus complex" in Ecotoxicology, 25, no. 8 (2016):1531-1542, https://doi.org/10.1007/s10646-016-1707-x . .