Prikaz osnovnih podataka o dokumentu

On the Asymmetric Induction in Proline-Catalyzed Aldol Reactions: Reagent-Controlled Addition Reactions of 2,2-Dimethyl-1,3-dioxane-5-one to Acyclic Chiral alpha-Branched Aldehydes

dc.creatorMarjanović-Trajković, Jasna
dc.creatorMilanović, Vesna D.
dc.creatorFerjančić, Zorana
dc.creatorSaičić, Radomir
dc.date.accessioned2018-11-22T00:39:20Z
dc.date.available2018-11-22T00:39:20Z
dc.date.issued2017
dc.identifier.issn1434-193X
dc.identifier.urihttps://cherry.chem.bg.ac.rs/handle/123456789/2410
dc.description.abstractReagent stereocontrol in the proline-catalyzed aldol reaction of 2,2-dimethyl-1,3-dioxane-5-one 1 with chiral aldehydes has been investigated. Synthetically useful levels of diastereoselectivity could be achieved in reactions with acyclic chiral alpha-oxy and alpha-amino aldehydes in both matched and mismatched cases. By using this reaction as a key step, two medicinally relevant azasugars, 1-deoxy-galactonojirimycin (9) and 2,5-dideoxy-2,5-imino-d-altritol (10), were efficiently synthesized.en
dc.publisherWiley-V C H Verlag Gmbh, Weinheim
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172027/RS//
dc.relationSerbian Academy of Sciences and Arts [F193]
dc.rightsrestrictedAccess
dc.sourceEuropean Journal of Organic Chemistry
dc.subjectSynthetic methodsen
dc.subjectOrganocatalysisen
dc.subjectAldol reactionsen
dc.subjectIminosugarsen
dc.subjectDiastereoselectivityen
dc.titleOn the Asymmetric Induction in Proline-Catalyzed Aldol Reactions: Reagent-Controlled Addition Reactions of 2,2-Dimethyl-1,3-dioxane-5-one to Acyclic Chiral alpha-Branched Aldehydesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractМилановић, Весна; Ферјанчић, Зорана; Саичић, Радомир; Марјановић-Трајковић, Јасна;
dc.citation.issue41
dc.citation.spage6146
dc.citation.epage6153
dc.identifier.wos000414849900007
dc.identifier.doi10.1002/ejoc.201701073
dc.citation.other(41): 6146-6153
dc.citation.rankM22
dc.description.otherSupplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3229]
dc.type.versionpublishedVersionen
dc.identifier.scopus2-s2.0-85033474381


Dokumenti

Thumbnail
Ime:
2408.pdf
Veličina:
892.8Kb
Format:
PDF
Otvaranje

Ovaj dokument se pojavljuje u sledećim kolekcijama

Prikaz osnovnih podataka o dokumentu