A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)
Само за регистроване кориснике
2017
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A catalytic asymmetric synthesis of (+)-aza-galacto-fagomine (AGF) - the most promising compound for the pharmacological chaperone therapy of Krabbe disease was accomplished in six steps, in 14% overall yield. The synthesis hinges on the combination of organocatalyzed aldolization and reductive hydrazination.
Кључне речи:
Aza-galactofagomine / Organocatalysis / Krabbe disease / Enantioselective synthesis / AzasugarsИзвор:
Tetrahedron, 2017, 73, 18, 2630-Издавач:
- Pergamon-Elsevier Science Ltd, Oxford
Финансирање / пројекти:
- Развој нових синтетичких метода и њихова примена у синтези природних производа и биолошки активних једињења (RS-MESTD-Basic Research (BR or ON)-172027)
- Serbian Academy of Sciences and Arts [F193]
Напомена:
- Peer-reviewed manuscript: http://cherry.chem.bg.ac.rs/handle/123456789/3025
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3026
DOI: 10.1016/j.tet.2017.03.052
ISSN: 0040-4020
WoS: 000400226000006
Scopus: 2-s2.0-85016011635
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Marjanović-Trajković, Jasna AU - Ferjančić, Zorana AU - Saičić, Radomir PY - 2017 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2452 AB - A catalytic asymmetric synthesis of (+)-aza-galacto-fagomine (AGF) - the most promising compound for the pharmacological chaperone therapy of Krabbe disease was accomplished in six steps, in 14% overall yield. The synthesis hinges on the combination of organocatalyzed aldolization and reductive hydrazination. PB - Pergamon-Elsevier Science Ltd, Oxford T2 - Tetrahedron T1 - A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF) VL - 73 IS - 18 SP - 2630 DO - 10.1016/j.tet.2017.03.052 ER -
@article{ author = "Marjanović-Trajković, Jasna and Ferjančić, Zorana and Saičić, Radomir", year = "2017", abstract = "A catalytic asymmetric synthesis of (+)-aza-galacto-fagomine (AGF) - the most promising compound for the pharmacological chaperone therapy of Krabbe disease was accomplished in six steps, in 14% overall yield. The synthesis hinges on the combination of organocatalyzed aldolization and reductive hydrazination.", publisher = "Pergamon-Elsevier Science Ltd, Oxford", journal = "Tetrahedron", title = "A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)", volume = "73", number = "18", pages = "2630", doi = "10.1016/j.tet.2017.03.052" }
Marjanović-Trajković, J., Ferjančić, Z.,& Saičić, R.. (2017). A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF). in Tetrahedron Pergamon-Elsevier Science Ltd, Oxford., 73(18), 2630. https://doi.org/10.1016/j.tet.2017.03.052
Marjanović-Trajković J, Ferjančić Z, Saičić R. A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF). in Tetrahedron. 2017;73(18):2630. doi:10.1016/j.tet.2017.03.052 .
Marjanović-Trajković, Jasna, Ferjančić, Zorana, Saičić, Radomir, "A short stereoselective synthesis of (+)-aza-galacto-fagomine (AGF)" in Tetrahedron, 73, no. 18 (2017):2630, https://doi.org/10.1016/j.tet.2017.03.052 . .