Total Synthesis of CrocaginA
Само за регистроване кориснике
2017
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
CrocaginA (1) combines an attractive molecular structure with an unusual biosynthesis and bioactivity. An efficient synthesis of crocaginA is presented that hinges on an early formation of the heterotricyclic core, an electrophilic amination, and the stereoselective hydrogenation of a tetrasubstituted double bond. This synthesis confirms the absolute configuration of crocaginA and provides access to the natural product and derivatives thereof for further biological testing.
Кључне речи:
electrophilic amination / hydrogenation / natural products / RiPPs / total synthesisИзвор:
Angewandte Chemie (International Edition), 2017, 56, 42, 12848-12851Издавач:
- Wiley-V C H Verlag Gmbh, Weinheim
Финансирање / пројекти:
- Deutsche Forschungsgemeinschaft (CIPSM)
- Deutsche Forschungsgemeinschaft [SFB 749]
Напомена:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3261
DOI: 10.1002/anie.201612641
ISSN: 1433-7851
PubMed: 28812331
WoS: 000412189700006
Scopus: 2-s2.0-85030637829
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Bihelović, Filip AU - Stichnoth, Desiree AU - Surup, Frank AU - Mueller, Rolf AU - Trauner, Dirk PY - 2017 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2532 AB - CrocaginA (1) combines an attractive molecular structure with an unusual biosynthesis and bioactivity. An efficient synthesis of crocaginA is presented that hinges on an early formation of the heterotricyclic core, an electrophilic amination, and the stereoselective hydrogenation of a tetrasubstituted double bond. This synthesis confirms the absolute configuration of crocaginA and provides access to the natural product and derivatives thereof for further biological testing. PB - Wiley-V C H Verlag Gmbh, Weinheim T2 - Angewandte Chemie (International Edition) T1 - Total Synthesis of CrocaginA VL - 56 IS - 42 SP - 12848 EP - 12851 DO - 10.1002/anie.201612641 ER -
@article{ author = "Bihelović, Filip and Stichnoth, Desiree and Surup, Frank and Mueller, Rolf and Trauner, Dirk", year = "2017", abstract = "CrocaginA (1) combines an attractive molecular structure with an unusual biosynthesis and bioactivity. An efficient synthesis of crocaginA is presented that hinges on an early formation of the heterotricyclic core, an electrophilic amination, and the stereoselective hydrogenation of a tetrasubstituted double bond. This synthesis confirms the absolute configuration of crocaginA and provides access to the natural product and derivatives thereof for further biological testing.", publisher = "Wiley-V C H Verlag Gmbh, Weinheim", journal = "Angewandte Chemie (International Edition)", title = "Total Synthesis of CrocaginA", volume = "56", number = "42", pages = "12848-12851", doi = "10.1002/anie.201612641" }
Bihelović, F., Stichnoth, D., Surup, F., Mueller, R.,& Trauner, D.. (2017). Total Synthesis of CrocaginA. in Angewandte Chemie (International Edition) Wiley-V C H Verlag Gmbh, Weinheim., 56(42), 12848-12851. https://doi.org/10.1002/anie.201612641
Bihelović F, Stichnoth D, Surup F, Mueller R, Trauner D. Total Synthesis of CrocaginA. in Angewandte Chemie (International Edition). 2017;56(42):12848-12851. doi:10.1002/anie.201612641 .
Bihelović, Filip, Stichnoth, Desiree, Surup, Frank, Mueller, Rolf, Trauner, Dirk, "Total Synthesis of CrocaginA" in Angewandte Chemie (International Edition), 56, no. 42 (2017):12848-12851, https://doi.org/10.1002/anie.201612641 . .