New forms of immunotherapies of allergic diseases
Nove forme imunoterapije alergijskih oboljenja
Article (Published version)
MetadataShow full item record
The prevalence of allergic disorders, such as hay fever and asthma has increased worldwide, mostly in westernized countries where up to 20 % of the population are affected. In recent years, a better understanding of the immunopathogenesis of allergic diseases has evolved, which has contributed to the development of novel more targeted forms of therapy. Allergen injection immunotherapy is the only treatment in current use with the curative potential. The use of modified allergens, allergen peptides and the use of novel adjuvant represent alternatives to conventional immunotherapy with potential for improved efficacy with less side effects. Although, immunomodulatory strategies provide a promising outlook for the treatment of allergic patients, more studies are needed in the future to address issues of efficacy, safety and long-term effects of altered immune responses.