Приказ основних података о документу

dc.creatorRašković, Brankica
dc.creatorPolović, Natalija
dc.date.accessioned2019-09-11T15:30:49Z
dc.date.available2017-03-29
dc.date.issued2016
dc.identifier.issn2210-8033
dc.identifier.urihttps://cherry.chem.bg.ac.rs/handle/123456789/3413
dc.description.abstractFicus carica, the common fig has been widely used for centuries for medicine as well as food. Fig latex is used for the treatments of cancer, inflammatory diseases, bacterial and gastrointestinal nematode infections, warts and skin diseases. The aim of the study was to investigate if some of the fig latex applications could be attributed to collagenase activity. The usage of figs in the Western Balkans indicated that the latex of unripe fruits is often used for treatments that could involve remodeling of connective tissue. Collagenase activity in fig latices collected in spring was twice as high as the one detected in summer. Collagenase improved diffusion of low-molecular-weight model molecule through the gelatin hydrogel. Fig latex collagenase was stable during boiling and in the simulated gastric conditions for up to 1 h. The presence of fig latex collagenase in traditional medicine preparations could increase treatment efficacy by hydrolyzing collagen present in extracellular matrix and facilitating the penetration of active molecules through the connective tissue. (C) 2016 Elsevier GmbH. All rights reserved.en
dc.publisherElsevier Gmbh, Urban & Fischer Verlag, Jena
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172049/RS//
dc.rightsembargoedAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceJournal of Herbal Medicine
dc.subjectWest Balkanen
dc.subjectFig latexen
dc.subjectCollagenaseen
dc.subjectFicus caricaen
dc.subjectExtracellular matrixen
dc.titleCollegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparationsen
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractПоловић, Наталија; Рашковић, Бранкица;
dc.citation.volume6
dc.citation.issue2
dc.citation.spage73
dc.citation.epage78
dc.identifier.wos000378670400004
dc.identifier.doi10.1016/j.hermed.2016.03.002
dc.citation.other6(2): 73-78
dc.citation.rankM23
dc.description.otherThis is peer-reviewed version of the following article: Raskovic, B. G.; Polovic, N. D. Collegenase Activity in Fig Latex Could Contribute to Its Efficacy in Ethnomedicinal Preparations. Journal of Herbal Medicine 2016, 6 (2), 73–78. [https://doi.org/10.1016/j.hermed.2016.03.002]
dc.type.versionacceptedVersionen
dc.identifier.scopus2-s2.0-84964355271
dc.identifier.fulltexthttps://cherry.chem.bg.ac.rs/bitstream/id/14883/Collegenase_activity_in_acc_2016.pdf


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Приказ основних података о документу