Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts
Аутори
Vujić, BojanVidaković, Vera
Jadranin, Milka
Novaković, Irena T.
Trifunović, Snežana S.
Tešević, Vele
Mandić, Boris
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal spec...ies. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.
Кључне речи:
Antimicrobial activity / Antioxidant potential / Helichrysum plicatum / Liquid chromatography-mass spectrometry (LC-MS) / Phenols / Solvent polarityИзвор:
Plants, 2020, 9, 3, 337-Издавач:
- MDPI
Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-172053)
- Процена екофизиолошког и генетичког диверзитета биљака у шумским екосистемима (RS-173011)
DOI: 10.3390/plants9030337
ISSN: 2223-7747
WoS: 000525315000029
Scopus: 2-s2.0-85082197649
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Vujić, Bojan AU - Vidaković, Vera AU - Jadranin, Milka AU - Novaković, Irena T. AU - Trifunović, Snežana S. AU - Tešević, Vele AU - Mandić, Boris PY - 2020 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3962 AB - Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol. PB - MDPI T2 - Plants T1 - Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts VL - 9 IS - 3 SP - 337 DO - 10.3390/plants9030337 ER -
@article{ author = "Vujić, Bojan and Vidaković, Vera and Jadranin, Milka and Novaković, Irena T. and Trifunović, Snežana S. and Tešević, Vele and Mandić, Boris", year = "2020", abstract = "Helichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.", publisher = "MDPI", journal = "Plants", title = "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts", volume = "9", number = "3", pages = "337", doi = "10.3390/plants9030337" }
Vujić, B., Vidaković, V., Jadranin, M., Novaković, I. T., Trifunović, S. S., Tešević, V.,& Mandić, B.. (2020). Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants MDPI., 9(3), 337. https://doi.org/10.3390/plants9030337
Vujić B, Vidaković V, Jadranin M, Novaković IT, Trifunović SS, Tešević V, Mandić B. Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts. in Plants. 2020;9(3):337. doi:10.3390/plants9030337 .
Vujić, Bojan, Vidaković, Vera, Jadranin, Milka, Novaković, Irena T., Trifunović, Snežana S., Tešević, Vele, Mandić, Boris, "Composition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extracts" in Plants, 9, no. 3 (2020):337, https://doi.org/10.3390/plants9030337 . .