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dc.creatorPetrović, G
dc.creatorSaičić, Radomir
dc.creatorČeković, Živorad
dc.date.accessioned2018-11-22T00:02:42Z
dc.date.available2018-11-22T00:02:42Z
dc.date.issued1999
dc.identifier.issn0936-5214
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/415
dc.description.abstractThe synthesis of acetyl scopine using tropine as a starting compound was achieved. Free radical phenylthio group transfer to the 6-position, in the reaction of N-carbethoxy nortropine-3 alpha-benzenesulfenate with hexabutylditin, is a key step of this synthetic approach to scopine. The reaction of N-carbethoxy nortropine-benzenesulfenate with tributyltin hydride in the presence of a radicophilic olefin involves Michael type alkylation at the 6-position of tropine skeleton affording 6-(2-carbethoxyethyl)-N-carbethoxy nortropine in 31% yield.en
dc.publisherGeorg Thieme Verlag, Stuttgart
dc.rightsrestrictedAccess
dc.sourceSynlett
dc.subject6,7-dehydrotropineen
dc.subjectscopineen
dc.subjecttropine benzenesulfenateen
dc.subjectintramolecular radical reactionsen
dc.subject1,5-hydrogen shiften
dc.titleSynthesis of acetyl scopine. Intramolecular reactions of N-carbethoxy nortropine-3 alpha-benzenesulfenateen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСаичић, Радомир; Петровиц, Г; Цековиц, З;
dc.citation.issue5
dc.citation.spage635
dc.citation.epage637
dc.identifier.wos000080790200042
dc.identifier.doi10.1055/s-1999-2658
dc.citation.other(5): 635-637
dc.citation.rankM21
dc.identifier.scopus2-s2.0-0141894152
dc.identifier.rcubKon_1389


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