Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues
Само за регистроване кориснике
2021
Аутори
Stojsavljević, AleksandarRovčanin, Marija
Rovčanin, Branislav
Miković, Željko
Jeremić, Ana
Perović, Milan
Manojlović, Dragan D.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Exposure to certain metals has been recognized as a risk factor for numerous complications in vulnerable population groups, particularly pregnant women. This investigation evaluated the levels of essential (Cr, Mn, Co, Cu, Zn, Se, Mo) and nonessential trace metals with recognized toxicity (Be, Al, Ti, V, Ni, Ga, As, Rb, Sr, Cd, Sb, Ba, Tl, Hg, Pb, Bi, Th, U), together with rare earth elements (Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb, Lu), and noble metals (Ru, Rh, Pd, Re, Os, Ir, Pt, Au, Ag) in the placental tissues of healthy pregnant women (n = 105). The selection of participants was undertaken with special reference to specific confounding factors that could influence the trace element profiles. Among trace elements, Zn was the most abundant and Lu was the least abundant. Cd and Os placental levels show a tendency to increase with women's age. Compared with literature data, high levels of Ni were found. This is the first study that provides the composition levels of es...sential and toxic trace elements, rare earth elements, and noble metals in human placental tissues. Also, for the first time, normal (reference) ranges for 50 (ultra)trace elements in placental tissues are proposed. Reference ranges are especially important in biomonitoring studies, which nowadays give increasing importance to the analysis of solid tissues instead of body fluids. Overall, the information provided in this study can serve as a starting point for further clinical trials and/or prediction of potential risks to pregnancy.
Кључне речи:
Biomonitoring / Placental tissue / Reference range / Trace elementИзвор:
Chemosphere, 2021, 285, 131518-Издавач:
- Elsevier
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200288 (Иновациони центар Хемијског факултета у Београду доо) (RS-MESTD-inst-2020-200288)
Напомена:
- Supplementary material: https://cherry.chem.bg.ac.rs/handle/123456789/4806
Повезане информације:
DOI: 10.1016/j.chemosphere.2021.131518
ISSN: 0045-6535
WoS: 000704464400009
Scopus: 2-s2.0-85109876630
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Stojsavljević, Aleksandar AU - Rovčanin, Marija AU - Rovčanin, Branislav AU - Miković, Željko AU - Jeremić, Ana AU - Perović, Milan AU - Manojlović, Dragan D. PY - 2021 UR - http://cherry.chem.bg.ac.rs/handle/123456789/4805 AB - Exposure to certain metals has been recognized as a risk factor for numerous complications in vulnerable population groups, particularly pregnant women. This investigation evaluated the levels of essential (Cr, Mn, Co, Cu, Zn, Se, Mo) and nonessential trace metals with recognized toxicity (Be, Al, Ti, V, Ni, Ga, As, Rb, Sr, Cd, Sb, Ba, Tl, Hg, Pb, Bi, Th, U), together with rare earth elements (Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb, Lu), and noble metals (Ru, Rh, Pd, Re, Os, Ir, Pt, Au, Ag) in the placental tissues of healthy pregnant women (n = 105). The selection of participants was undertaken with special reference to specific confounding factors that could influence the trace element profiles. Among trace elements, Zn was the most abundant and Lu was the least abundant. Cd and Os placental levels show a tendency to increase with women's age. Compared with literature data, high levels of Ni were found. This is the first study that provides the composition levels of essential and toxic trace elements, rare earth elements, and noble metals in human placental tissues. Also, for the first time, normal (reference) ranges for 50 (ultra)trace elements in placental tissues are proposed. Reference ranges are especially important in biomonitoring studies, which nowadays give increasing importance to the analysis of solid tissues instead of body fluids. Overall, the information provided in this study can serve as a starting point for further clinical trials and/or prediction of potential risks to pregnancy. PB - Elsevier T2 - Chemosphere T1 - Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues VL - 285 SP - 131518 DO - 10.1016/j.chemosphere.2021.131518 ER -
@article{ author = "Stojsavljević, Aleksandar and Rovčanin, Marija and Rovčanin, Branislav and Miković, Željko and Jeremić, Ana and Perović, Milan and Manojlović, Dragan D.", year = "2021", abstract = "Exposure to certain metals has been recognized as a risk factor for numerous complications in vulnerable population groups, particularly pregnant women. This investigation evaluated the levels of essential (Cr, Mn, Co, Cu, Zn, Se, Mo) and nonessential trace metals with recognized toxicity (Be, Al, Ti, V, Ni, Ga, As, Rb, Sr, Cd, Sb, Ba, Tl, Hg, Pb, Bi, Th, U), together with rare earth elements (Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb, Lu), and noble metals (Ru, Rh, Pd, Re, Os, Ir, Pt, Au, Ag) in the placental tissues of healthy pregnant women (n = 105). The selection of participants was undertaken with special reference to specific confounding factors that could influence the trace element profiles. Among trace elements, Zn was the most abundant and Lu was the least abundant. Cd and Os placental levels show a tendency to increase with women's age. Compared with literature data, high levels of Ni were found. This is the first study that provides the composition levels of essential and toxic trace elements, rare earth elements, and noble metals in human placental tissues. Also, for the first time, normal (reference) ranges for 50 (ultra)trace elements in placental tissues are proposed. Reference ranges are especially important in biomonitoring studies, which nowadays give increasing importance to the analysis of solid tissues instead of body fluids. Overall, the information provided in this study can serve as a starting point for further clinical trials and/or prediction of potential risks to pregnancy.", publisher = "Elsevier", journal = "Chemosphere", title = "Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues", volume = "285", pages = "131518", doi = "10.1016/j.chemosphere.2021.131518" }
Stojsavljević, A., Rovčanin, M., Rovčanin, B., Miković, Ž., Jeremić, A., Perović, M.,& Manojlović, D. D.. (2021). Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues. in Chemosphere Elsevier., 285, 131518. https://doi.org/10.1016/j.chemosphere.2021.131518
Stojsavljević A, Rovčanin M, Rovčanin B, Miković Ž, Jeremić A, Perović M, Manojlović DD. Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues. in Chemosphere. 2021;285:131518. doi:10.1016/j.chemosphere.2021.131518 .
Stojsavljević, Aleksandar, Rovčanin, Marija, Rovčanin, Branislav, Miković, Željko, Jeremić, Ana, Perović, Milan, Manojlović, Dragan D., "Human biomonitoring of essential, nonessential, rare earth, and noble elements in placental tissues" in Chemosphere, 285 (2021):131518, https://doi.org/10.1016/j.chemosphere.2021.131518 . .