Determination of diazepam by flow-injection with amperometric detection in beverages
Аутори
Lolić, AleksandarAntunović, Vesna R.
Tešanović, Slavna
Perušković, Danica S.
Stevanović, Nikola R.
Baošić, Rada
Nikolić, Snežana
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Diazepam belongs to the group of benzodiazepine drugs, and its consumption with alcohol enhances its sedative effect and absorption rate. That is why it is often used as “date rape drug” [1]. In our experiments we applied the flow injection system on diazepam determination on a bare glassy carbon electrode. The electrochemical determination of diazepam is based on reduction of the azomethine group yielding a dyhidrodiazepam. The single cathodic peak is caused by the reduction of diazepam by a two electron change. The reduction potential is highly dependent on pH value of the electrolyte, shifting to more negative potentials with higher pH [2].
Кључне речи:
Diazepam / Flow injection / AmperometryИзвор:
1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31, 2016, 37-37Издавач:
- ISEP Instituto Superior de Engenharia do Porto
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - CONF AU - Lolić, Aleksandar AU - Antunović, Vesna R. AU - Tešanović, Slavna AU - Perušković, Danica S. AU - Stevanović, Nikola R. AU - Baošić, Rada AU - Nikolić, Snežana PY - 2016 UR - http://cherry.chem.bg.ac.rs/handle/123456789/4994 AB - Diazepam belongs to the group of benzodiazepine drugs, and its consumption with alcohol enhances its sedative effect and absorption rate. That is why it is often used as “date rape drug” [1]. In our experiments we applied the flow injection system on diazepam determination on a bare glassy carbon electrode. The electrochemical determination of diazepam is based on reduction of the azomethine group yielding a dyhidrodiazepam. The single cathodic peak is caused by the reduction of diazepam by a two electron change. The reduction potential is highly dependent on pH value of the electrolyte, shifting to more negative potentials with higher pH [2]. PB - ISEP Instituto Superior de Engenharia do Porto C3 - 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31 T1 - Determination of diazepam by flow-injection with amperometric detection in beverages SP - 37 EP - 37 UR - https://hdl.handle.net/21.15107/rcub_cherry_4994 ER -
@conference{ author = "Lolić, Aleksandar and Antunović, Vesna R. and Tešanović, Slavna and Perušković, Danica S. and Stevanović, Nikola R. and Baošić, Rada and Nikolić, Snežana", year = "2016", abstract = "Diazepam belongs to the group of benzodiazepine drugs, and its consumption with alcohol enhances its sedative effect and absorption rate. That is why it is often used as “date rape drug” [1]. In our experiments we applied the flow injection system on diazepam determination on a bare glassy carbon electrode. The electrochemical determination of diazepam is based on reduction of the azomethine group yielding a dyhidrodiazepam. The single cathodic peak is caused by the reduction of diazepam by a two electron change. The reduction potential is highly dependent on pH value of the electrolyte, shifting to more negative potentials with higher pH [2].", publisher = "ISEP Instituto Superior de Engenharia do Porto", journal = "1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31", title = "Determination of diazepam by flow-injection with amperometric detection in beverages", pages = "37-37", url = "https://hdl.handle.net/21.15107/rcub_cherry_4994" }
Lolić, A., Antunović, V. R., Tešanović, S., Perušković, D. S., Stevanović, N. R., Baošić, R.,& Nikolić, S.. (2016). Determination of diazepam by flow-injection with amperometric detection in beverages. in 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31 ISEP Instituto Superior de Engenharia do Porto., 37-37. https://hdl.handle.net/21.15107/rcub_cherry_4994
Lolić A, Antunović VR, Tešanović S, Perušković DS, Stevanović NR, Baošić R, Nikolić S. Determination of diazepam by flow-injection with amperometric detection in beverages. in 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31. 2016;:37-37. https://hdl.handle.net/21.15107/rcub_cherry_4994 .
Lolić, Aleksandar, Antunović, Vesna R., Tešanović, Slavna, Perušković, Danica S., Stevanović, Nikola R., Baošić, Rada, Nikolić, Snežana, "Determination of diazepam by flow-injection with amperometric detection in beverages" in 1st workshop on Electrochemistry Devices (Bio)Sensors, October 13-14, 2016, Porto, Portugal, Book of Abstracts pp 31 (2016):37-37, https://hdl.handle.net/21.15107/rcub_cherry_4994 .