Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity
Аутори
Aćimović, Milica G.Pezo, Lato
Čabarkapa, Ivana
Trudić, Anika
Stanković-Jeremić, Jovana
Varga, Ana
Lončar, Biljana
Šovljanski, Olja
Tešević, Vele
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This study aimed to investigate the chemical composition of steam distillate essential oil
and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence
of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore,
their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different
from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among
the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the
tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration
(MBC/MFC) were 14.20 and 28.4 µL mL−1
, respectively). MIC and MBC values of other tested
bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged
from 28.40/56.81 to 56.81–113.6...3 µL mL−1
. Antibiotic susceptibility patterns for the analyzed eight
respiratory-associated microorganisms showed an intermediate level of resistance to commonly used
antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the
antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess
remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an
alternative to conventional antibiotic therapy
Кључне речи:
Salvia officinalis / essential oil / hydrolate / weather conditions / antimicrobial activity / in vitroИзвор:
Processes, 2022, 10, 8, 1608-Издавач:
- MDPI
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200051 (Институт за општу и физичку хемију, Београд) (RS-200051)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200012 (Институт за испитивање материјала Србије - ИМС, Београд) (RS-200012)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200032 (Научни институт за ратарство и повртарство, Нови Сад) (RS-200032)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200134 (Универзитет у Новом Саду, Технолошки факултет) (RS-200134)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200125 (Универзитет у Новом Саду, Природно-математички факултет) (RS-200125)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-200026)
Напомена:
- Supplementary material: https://cherry.chem.bg.ac.rs/handle/123456789/5618
Повезане информације:
DOI: 10.3390/pr10081608
ISSN: 2227-9717
WoS: 00084577460000
Scopus: 2-s2.0-85137589816
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Aćimović, Milica G. AU - Pezo, Lato AU - Čabarkapa, Ivana AU - Trudić, Anika AU - Stanković-Jeremić, Jovana AU - Varga, Ana AU - Lončar, Biljana AU - Šovljanski, Olja AU - Tešević, Vele PY - 2022 UR - http://cherry.chem.bg.ac.rs/handle/123456789/5614 AB - This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 µL mL−1 , respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 µL mL−1 . Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy PB - MDPI T2 - Processes T1 - Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity VL - 10 IS - 8 SP - 1608 DO - 10.3390/pr10081608 ER -
@article{ author = "Aćimović, Milica G. and Pezo, Lato and Čabarkapa, Ivana and Trudić, Anika and Stanković-Jeremić, Jovana and Varga, Ana and Lončar, Biljana and Šovljanski, Olja and Tešević, Vele", year = "2022", abstract = "This study aimed to investigate the chemical composition of steam distillate essential oil and corresponding hydrolate obtained from S. officinalis grown in Serbia, as well as the influence of weather conditions (temperature and precipitations) on their chemical profiles. Furthermore, their antimicrobial activity was investigated in vitro. The main compounds in essential oil were cisthujone, followed by camphor, trans-thujone, and 1,8-cineole, while hydrolate was slightly different from the essential oil, with camphor, cis-thujone, and 1,8-cineole as the main compounds. Among the eight respiratory-associated microorganisms, Klebsiella oxytoca was the most sensitive to the tested EOs (minimum inhibitory concentration (MIC)/minimal bactericidal/fungicidal concentration (MBC/MFC) were 14.20 and 28.4 µL mL−1 , respectively). MIC and MBC values of other tested bacteria ranged between 28.40 and 227.25 µL mL−1 while for Candida albicans MIC/MFC ranged from 28.40/56.81 to 56.81–113.63 µL mL−1 . Antibiotic susceptibility patterns for the analyzed eight respiratory-associated microorganisms showed an intermediate level of resistance to commonly used antibiotics such as ampicillin, levofloxacin, and ciprofloxacin. As a preliminary approach to the antimicrobial profiling of the tested EO, the obtained results revealed that the tested samples possess remarkable antibacterial activities and could be used to develop pharmaceutical formulations as an alternative to conventional antibiotic therapy", publisher = "MDPI", journal = "Processes", title = "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity", volume = "10", number = "8", pages = "1608", doi = "10.3390/pr10081608" }
Aćimović, M. G., Pezo, L., Čabarkapa, I., Trudić, A., Stanković-Jeremić, J., Varga, A., Lončar, B., Šovljanski, O.,& Tešević, V.. (2022). Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes MDPI., 10(8), 1608. https://doi.org/10.3390/pr10081608
Aćimović MG, Pezo L, Čabarkapa I, Trudić A, Stanković-Jeremić J, Varga A, Lončar B, Šovljanski O, Tešević V. Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity. in Processes. 2022;10(8):1608. doi:10.3390/pr10081608 .
Aćimović, Milica G., Pezo, Lato, Čabarkapa, Ivana, Trudić, Anika, Stanković-Jeremić, Jovana, Varga, Ana, Lončar, Biljana, Šovljanski, Olja, Tešević, Vele, "Variation of Salvia officinalis L. Essential Oil and Hydrolate Composition and Their Antimicrobial Activity" in Processes, 10, no. 8 (2022):1608, https://doi.org/10.3390/pr10081608 . .