Reversed-phase thin-layer chromatography of stereodefined 2-alkylidene-4-oxothiazolidines and 1,2-dithioles
No Thumbnail
Authors
Natić, MajaMarković, R.
Anđelković, Katarina K.
Milojković-Opsenica, Dušanka
Tešić, Živoslav Lj.
Article (Published version)
Metadata
Show full item recordAbstract
Experimental R, values for a series of functionalized 2-alkylidene-4-oxothiazolidines and 1,2-dithioles have been determined by reversed-phase TLC on RP-18 silica plates. Binary mixtures of methanol and water, tetrahydrofuran and water, and acetone and water were used as mobile phases. R-M(0) values were determined for these mobile phase mixtures by linear extrapolation to 0% (v/v) organic modifier. The lipophilicity, C-0, was calculated as the ratio of the intercept and slope values. Chromatographically obtained lipophilicity data correlated well with calculated log P values.
Keywords:
2-alkylidene-4-oxothiazolidines / 1,2-dithioles / reversed-phase TLC / lipophilicitySource:
Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 2004, 17, 5, 323-327Publisher:
- Research Inst Medicinal Plants, Budakalasz
DOI: 10.1556/JPC.17.2004.5.1
ISSN: 0933-4173
WoS: 000225586900001
Scopus: 2-s2.0-9744220434
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Natić, Maja AU - Marković, R. AU - Anđelković, Katarina K. AU - Milojković-Opsenica, Dušanka AU - Tešić, Živoslav Lj. PY - 2004 UR - https://cherry.chem.bg.ac.rs/handle/123456789/673 AB - Experimental R, values for a series of functionalized 2-alkylidene-4-oxothiazolidines and 1,2-dithioles have been determined by reversed-phase TLC on RP-18 silica plates. Binary mixtures of methanol and water, tetrahydrofuran and water, and acetone and water were used as mobile phases. R-M(0) values were determined for these mobile phase mixtures by linear extrapolation to 0% (v/v) organic modifier. The lipophilicity, C-0, was calculated as the ratio of the intercept and slope values. Chromatographically obtained lipophilicity data correlated well with calculated log P values. PB - Research Inst Medicinal Plants, Budakalasz T2 - Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography T1 - Reversed-phase thin-layer chromatography of stereodefined 2-alkylidene-4-oxothiazolidines and 1,2-dithioles VL - 17 IS - 5 SP - 323 EP - 327 DO - 10.1556/JPC.17.2004.5.1 ER -
@article{ author = "Natić, Maja and Marković, R. and Anđelković, Katarina K. and Milojković-Opsenica, Dušanka and Tešić, Živoslav Lj.", year = "2004", abstract = "Experimental R, values for a series of functionalized 2-alkylidene-4-oxothiazolidines and 1,2-dithioles have been determined by reversed-phase TLC on RP-18 silica plates. Binary mixtures of methanol and water, tetrahydrofuran and water, and acetone and water were used as mobile phases. R-M(0) values were determined for these mobile phase mixtures by linear extrapolation to 0% (v/v) organic modifier. The lipophilicity, C-0, was calculated as the ratio of the intercept and slope values. Chromatographically obtained lipophilicity data correlated well with calculated log P values.", publisher = "Research Inst Medicinal Plants, Budakalasz", journal = "Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography", title = "Reversed-phase thin-layer chromatography of stereodefined 2-alkylidene-4-oxothiazolidines and 1,2-dithioles", volume = "17", number = "5", pages = "323-327", doi = "10.1556/JPC.17.2004.5.1" }
Natić, M., Marković, R., Anđelković, K. K., Milojković-Opsenica, D.,& Tešić, Ž. Lj.. (2004). Reversed-phase thin-layer chromatography of stereodefined 2-alkylidene-4-oxothiazolidines and 1,2-dithioles. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography Research Inst Medicinal Plants, Budakalasz., 17(5), 323-327. https://doi.org/10.1556/JPC.17.2004.5.1
Natić M, Marković R, Anđelković KK, Milojković-Opsenica D, Tešić ŽL. Reversed-phase thin-layer chromatography of stereodefined 2-alkylidene-4-oxothiazolidines and 1,2-dithioles. in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography. 2004;17(5):323-327. doi:10.1556/JPC.17.2004.5.1 .
Natić, Maja, Marković, R., Anđelković, Katarina K., Milojković-Opsenica, Dušanka, Tešić, Živoslav Lj., "Reversed-phase thin-layer chromatography of stereodefined 2-alkylidene-4-oxothiazolidines and 1,2-dithioles" in Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography, 17, no. 5 (2004):323-327, https://doi.org/10.1556/JPC.17.2004.5.1 . .