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dc.creatorSrcek, VG
dc.creatorCajavec, S
dc.creatorSladić, Dušan
dc.creatorKniewald, Z
dc.date.accessioned2018-11-22T00:07:46Z
dc.date.available2018-11-22T00:07:46Z
dc.date.issued2004
dc.identifier.issn0920-9069
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/695
dc.description.abstractProduction of Aujeszky's disease virus (ADV) from BHK 21 C13 suspension cells using a simple harvest and multiple harvest process mode was examined. We studied growth kinetics of BHK 21 C31 cells in 750 ml spinner. ask containing 500 ml of culture medium. In the simple harvest process of ADV production, 425 ml of virus harvest was obtained with a virus titer of 10(6.4) TCID50 ml(-1) which corresponds to 10,676 doses of vaccine. The multiple harvest process resulted in 850 ml of virus harvest with a virus titer of 10(6.5) TCID50 ml(-1) corresponding to 26,877 AD vaccine doses. In conclusion, the multiple harvest process mode using BHK 21 C13 can be considered as a favorable process to produce ADV.en
dc.publisherSpringer, Dordrecht
dc.rightsrestrictedAccess
dc.sourceCytotechnology
dc.subjectAujeszky's disease virusen
dc.subjectbaby hamster kidney cellsen
dc.subjectbiomass productionen
dc.subjectmultiple harvest processen
dc.subjectspinner flasken
dc.titleBHK21C13 cells for Aujeszky's disease virus production using the multiple harvest processen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСрцек, ВГ; Сладић, Душан; Цајавец, С; Книеwалд, З;
dc.citation.volume45
dc.citation.issue3
dc.citation.spage101
dc.citation.epage106
dc.identifier.wos000228178400001
dc.identifier.doi10.1007/s10616-004-2551-z
dc.citation.other45(3): 101-106
dc.citation.rankM23
dc.identifier.pmid19003247
dc.description.otherFree full text: [http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3450169&blobtype=pdf]
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-17644381945
dc.identifier.rcubKon_1648


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