Allosteric regulation of the conformational dynamics of a cavitand receptor
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2006
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Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative H-1 NMR studies have revealed that the rate of the conformational isomerization of 1 can be modulated using the external addition of acid. As 1 maintains its vase-like conformation in an acidic environment, ample opportunities for controlling the kinetics of molecular recognition, and thus reactivity, in this and related receptors have arisen.
Izvor:
Organic Letters, 2006, 8, 17, 3697-3700Izdavač:
- Amer Chemical Soc, Washington
DOI: 10.1021/ol0612760
ISSN: 1523-7060
PubMed: 16898795
WoS: 000239655500020
Scopus: 2-s2.0-33748584333
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Yan, Zhiqing AU - Chang, Yuning AU - Mayo, Dennis AU - Maslak, Veselin AU - Xia, Shijing AU - Bađić, Jovica D. PY - 2006 UR - https://cherry.chem.bg.ac.rs/handle/123456789/795 AB - Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative H-1 NMR studies have revealed that the rate of the conformational isomerization of 1 can be modulated using the external addition of acid. As 1 maintains its vase-like conformation in an acidic environment, ample opportunities for controlling the kinetics of molecular recognition, and thus reactivity, in this and related receptors have arisen. PB - Amer Chemical Soc, Washington T2 - Organic Letters T1 - Allosteric regulation of the conformational dynamics of a cavitand receptor VL - 8 IS - 17 SP - 3697 EP - 3700 DO - 10.1021/ol0612760 ER -
@article{ author = "Yan, Zhiqing and Chang, Yuning and Mayo, Dennis and Maslak, Veselin and Xia, Shijing and Bađić, Jovica D.", year = "2006", abstract = "Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative H-1 NMR studies have revealed that the rate of the conformational isomerization of 1 can be modulated using the external addition of acid. As 1 maintains its vase-like conformation in an acidic environment, ample opportunities for controlling the kinetics of molecular recognition, and thus reactivity, in this and related receptors have arisen.", publisher = "Amer Chemical Soc, Washington", journal = "Organic Letters", title = "Allosteric regulation of the conformational dynamics of a cavitand receptor", volume = "8", number = "17", pages = "3697-3700", doi = "10.1021/ol0612760" }
Yan, Z., Chang, Y., Mayo, D., Maslak, V., Xia, S.,& Bađić, J. D.. (2006). Allosteric regulation of the conformational dynamics of a cavitand receptor. in Organic Letters Amer Chemical Soc, Washington., 8(17), 3697-3700. https://doi.org/10.1021/ol0612760
Yan Z, Chang Y, Mayo D, Maslak V, Xia S, Bađić JD. Allosteric regulation of the conformational dynamics of a cavitand receptor. in Organic Letters. 2006;8(17):3697-3700. doi:10.1021/ol0612760 .
Yan, Zhiqing, Chang, Yuning, Mayo, Dennis, Maslak, Veselin, Xia, Shijing, Bađić, Jovica D., "Allosteric regulation of the conformational dynamics of a cavitand receptor" in Organic Letters, 8, no. 17 (2006):3697-3700, https://doi.org/10.1021/ol0612760 . .