Improved procedure for the preparation of cis-2,4-dimethylglutaranhydride
Addition of 2.5 mol% DBU to a mixture of isomeric 2,4-dimethylglutaric anhydrides in ethyl acetate promotes crystallization-induced transformation, affording the pure cis-2,4-dimethylglutaric anhydride in 87% yield.
Keywords:crystallization / DBU / 2,4-dimethylglutaric anhydride / isomerization
Source:Synthetic Communications, 2006, 36, 17, 2559-2562
- Taylor & Francis Inc, Philadelphia