Further guaianolides from Amphoricarpos neumayeri ssp murbeckii from Montenegro
Milosavljević, Slobodan M.
Article (Published version)
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The aerial parts of Amphoricarpos neumayeri ssp. murbeckii afforded eleven guaianolides with the same relative (1 alpha H,4 beta H,5 alpha H, 7 alpha H) configuration of the basic skeleton. All of them contained a CH2OX (X = H, acetyl or isovaleroyl) group in 4 alpha-position, typical for amphoricarpolides. Four compounds (1-4) were isolated before from the same species, originating from different localities. Guaianolides 5-11 are new compounds. Compounds 7 and 8 were epoxidized at the 10 alpha(14)-position. Instead of the Delta(11(13))-double bond, observed in all previously isolated guaianolides from the same species, the four lactones contained 11 alpha,13-diol (8-10) or 11 alpha-OH, 13-chloro (11) moieties respectively.
Keywords:Amphoricarpos neumayeri ssp murbeckii / sesquiterpene laetones / guaianolides
Source:Zeitschrift fur Naturforschung. Section B: Journal of Chemical Sciences, 2006, 61, 11, 1437-1442
- Verlag Z Naturforsch, Tubingen