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Coordination of hydralazine with Cu2+ at acidic pH promotes its oxidative degradation at neutral pH
(Elsevier, 2023)
Hydralazine (HL), a frequently prescribed oral antihypertensive drug, shows redox interactions with transition metals such as copper that are not fully understood. Copper may be present at high concentrations in the digestive ...
The formation of Fe3+-doxycycline complex is pH dependent: implications to doxycycline bioavailability
(Springer, 2023)
The interactions of drugs with iron are of interest in relation to the potential effects of iron-rich foods and iron supplements on sorption and bioavailability. Doxycycline (DOX), a member of the tetracycline class of ...
Intramolecular Dearomative Inverse-Electron-Demand Diels Alder Strategy for the Total Synthesis of (+)-Alstonlarsine A
(American Chemical Society, 2023)
An evolution of a synthetic route leading to a successful enantioselective total synthesis of monoterpenoid indole alkaloid (+)-alstonlarsine A is represented. The unique 9-azatricyclo[4.3.1.03,8]decane core was assembled ...