Chemical Characterization of Lippia Alba Essential Oil: An Alternative to Control Green Molds
2011
Authors
Glamočlija, JasminaSoković, Marina
Tešević, Vele
Linde, Giani Andrea
Colauto, Nelson Barros
Article (Published version)
Metadata
Show full item recordAbstract
The essential oil of Lippia alba is reported as an antifungal against human pathogenic microorganisms but few articles report its use as an alternative to synthetic fungicides on green mould control. The objective of this study was to determine chemical characteristics of L. alba essential oil and its antifungal activity against green molds as an alternative to synthetic fungicides. Essential oil was extracted by Clevenger hydrodistillation, characterized by GC-MS analysis, and the structure of the main compounds confirmed by H-1 and C-13-NMR spectroscopy. Microdilution assays evaluated the essential oil minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Commercial fungicides Ketoconazole and Bifonazole were used as control. Essential oil yield is of 0.15% and the major components are neral (33.32%) and geranial (50.94%). The L. alba essential oil has MIC of 0.300-1.250 mg/mL and MFC of 0.600-1.250 mg/mL. Ketoconazole and Bifonazole show MIC ranging from... 0.025-0.500 to 0.100-0.200 mg/mL, and MFC ranging from 0.250-0.100 to 0.200-0.250 mg/mL, respectively. L. alba essential oil is classified as citral type and the results indicate that it is a potential alternative to synthetic fungicides.
Keywords:
antifungal / essential oil / neral / geranial / Lippia albaSource:
Brazilian Journal of Microbiology, 2011, 42, 4, 1537-1546Publisher:
- Soc Brasileira Microbiologia, Sao Paulo
Funding / projects:
- Characterization and application of fungal metabolites and assessment of new biofungicides potential (RS-MESTD-Basic Research (BR or ON)-173032)
- Natural products of wild, cultivated and edible plants: structure and bioactivity determination (RS-MESTD-Basic Research (BR or ON)-172053)
- Paranaense University
DOI: 10.1590/S1517-83822011000400041
ISSN: 1517-8382
PubMed: 24031788
WoS: 000300430600041
Scopus: 2-s2.0-84857417473
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Glamočlija, Jasmina AU - Soković, Marina AU - Tešević, Vele AU - Linde, Giani Andrea AU - Colauto, Nelson Barros PY - 2011 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1250 AB - The essential oil of Lippia alba is reported as an antifungal against human pathogenic microorganisms but few articles report its use as an alternative to synthetic fungicides on green mould control. The objective of this study was to determine chemical characteristics of L. alba essential oil and its antifungal activity against green molds as an alternative to synthetic fungicides. Essential oil was extracted by Clevenger hydrodistillation, characterized by GC-MS analysis, and the structure of the main compounds confirmed by H-1 and C-13-NMR spectroscopy. Microdilution assays evaluated the essential oil minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Commercial fungicides Ketoconazole and Bifonazole were used as control. Essential oil yield is of 0.15% and the major components are neral (33.32%) and geranial (50.94%). The L. alba essential oil has MIC of 0.300-1.250 mg/mL and MFC of 0.600-1.250 mg/mL. Ketoconazole and Bifonazole show MIC ranging from 0.025-0.500 to 0.100-0.200 mg/mL, and MFC ranging from 0.250-0.100 to 0.200-0.250 mg/mL, respectively. L. alba essential oil is classified as citral type and the results indicate that it is a potential alternative to synthetic fungicides. PB - Soc Brasileira Microbiologia, Sao Paulo T2 - Brazilian Journal of Microbiology T1 - Chemical Characterization of Lippia Alba Essential Oil: An Alternative to Control Green Molds VL - 42 IS - 4 SP - 1537 EP - 1546 DO - 10.1590/S1517-83822011000400041 ER -
@article{ author = "Glamočlija, Jasmina and Soković, Marina and Tešević, Vele and Linde, Giani Andrea and Colauto, Nelson Barros", year = "2011", abstract = "The essential oil of Lippia alba is reported as an antifungal against human pathogenic microorganisms but few articles report its use as an alternative to synthetic fungicides on green mould control. The objective of this study was to determine chemical characteristics of L. alba essential oil and its antifungal activity against green molds as an alternative to synthetic fungicides. Essential oil was extracted by Clevenger hydrodistillation, characterized by GC-MS analysis, and the structure of the main compounds confirmed by H-1 and C-13-NMR spectroscopy. Microdilution assays evaluated the essential oil minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Commercial fungicides Ketoconazole and Bifonazole were used as control. Essential oil yield is of 0.15% and the major components are neral (33.32%) and geranial (50.94%). The L. alba essential oil has MIC of 0.300-1.250 mg/mL and MFC of 0.600-1.250 mg/mL. Ketoconazole and Bifonazole show MIC ranging from 0.025-0.500 to 0.100-0.200 mg/mL, and MFC ranging from 0.250-0.100 to 0.200-0.250 mg/mL, respectively. L. alba essential oil is classified as citral type and the results indicate that it is a potential alternative to synthetic fungicides.", publisher = "Soc Brasileira Microbiologia, Sao Paulo", journal = "Brazilian Journal of Microbiology", title = "Chemical Characterization of Lippia Alba Essential Oil: An Alternative to Control Green Molds", volume = "42", number = "4", pages = "1537-1546", doi = "10.1590/S1517-83822011000400041" }
Glamočlija, J., Soković, M., Tešević, V., Linde, G. A.,& Colauto, N. B.. (2011). Chemical Characterization of Lippia Alba Essential Oil: An Alternative to Control Green Molds. in Brazilian Journal of Microbiology Soc Brasileira Microbiologia, Sao Paulo., 42(4), 1537-1546. https://doi.org/10.1590/S1517-83822011000400041
Glamočlija J, Soković M, Tešević V, Linde GA, Colauto NB. Chemical Characterization of Lippia Alba Essential Oil: An Alternative to Control Green Molds. in Brazilian Journal of Microbiology. 2011;42(4):1537-1546. doi:10.1590/S1517-83822011000400041 .
Glamočlija, Jasmina, Soković, Marina, Tešević, Vele, Linde, Giani Andrea, Colauto, Nelson Barros, "Chemical Characterization of Lippia Alba Essential Oil: An Alternative to Control Green Molds" in Brazilian Journal of Microbiology, 42, no. 4 (2011):1537-1546, https://doi.org/10.1590/S1517-83822011000400041 . .