Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria
Abstract
A phytochemical investigation conducted on a folise lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina led to a mixture of methylated depsidones which showed acetylcholinesterase inhibition activity (2 mu g) in the acetylcholinesterase inhibition test on thin-layer chromatography plate. Present results indicate for the first time the potential of methylated depsidones in searching for these inhibitors, which still represent the best drugs currently available for the management of Alzheimer's disease.
Keywords:
Lobariaceae / Phytochemistry / Depsidones / Alzheimer's diseaseSource:
Asian Journal of Chemistry, 2012, 24, 7, 3261-3262Publisher:
- Asian Journal Of Chemistry, Sahibabad
Funding / projects:
- Natural products of wild, cultivated and edible plants: structure and bioactivity determination (RS-MESTD-Basic Research (BR or ON)-172053)
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Pejin, Boris AU - Tommonaro, G. AU - Iodice, Carmine AU - Tešević, Vele AU - Vajs, Vlatka PY - 2012 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1306 AB - A phytochemical investigation conducted on a folise lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina led to a mixture of methylated depsidones which showed acetylcholinesterase inhibition activity (2 mu g) in the acetylcholinesterase inhibition test on thin-layer chromatography plate. Present results indicate for the first time the potential of methylated depsidones in searching for these inhibitors, which still represent the best drugs currently available for the management of Alzheimer's disease. PB - Asian Journal Of Chemistry, Sahibabad T2 - Asian Journal of Chemistry T1 - Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria VL - 24 IS - 7 SP - 3261 EP - 3262 UR - https://hdl.handle.net/21.15107/rcub_cherry_1306 ER -
@article{ author = "Pejin, Boris and Tommonaro, G. and Iodice, Carmine and Tešević, Vele and Vajs, Vlatka", year = "2012", abstract = "A phytochemical investigation conducted on a folise lichen, Lobaria pulmonaria (L.) Hoffm. (Lobariaceae), from Bosnia and Herzegovina led to a mixture of methylated depsidones which showed acetylcholinesterase inhibition activity (2 mu g) in the acetylcholinesterase inhibition test on thin-layer chromatography plate. Present results indicate for the first time the potential of methylated depsidones in searching for these inhibitors, which still represent the best drugs currently available for the management of Alzheimer's disease.", publisher = "Asian Journal Of Chemistry, Sahibabad", journal = "Asian Journal of Chemistry", title = "Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria", volume = "24", number = "7", pages = "3261-3262", url = "https://hdl.handle.net/21.15107/rcub_cherry_1306" }
Pejin, B., Tommonaro, G., Iodice, C., Tešević, V.,& Vajs, V.. (2012). Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria. in Asian Journal of Chemistry Asian Journal Of Chemistry, Sahibabad., 24(7), 3261-3262. https://hdl.handle.net/21.15107/rcub_cherry_1306
Pejin B, Tommonaro G, Iodice C, Tešević V, Vajs V. Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria. in Asian Journal of Chemistry. 2012;24(7):3261-3262. https://hdl.handle.net/21.15107/rcub_cherry_1306 .
Pejin, Boris, Tommonaro, G., Iodice, Carmine, Tešević, Vele, Vajs, Vlatka, "Acetylcholinesterase Inhibition Activity of a Mixture of Methylated Depsidones from the Lichen Lobaria pulmonaria" in Asian Journal of Chemistry, 24, no. 7 (2012):3261-3262, https://hdl.handle.net/21.15107/rcub_cherry_1306 .