Приказ основних података о документу
Synthesis and antimicrobial activity of azepine and thiepine derivatives
dc.creator | Božinović, Nina S. | |
dc.creator | Novaković, Irena T. | |
dc.creator | Kostić-Rajačić, Slađana | |
dc.creator | Opsenica, Igor | |
dc.creator | Šolaja, Bogdan A. | |
dc.date.accessioned | 2018-11-22T00:32:07Z | |
dc.date.available | 2018-11-22T00:32:07Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 0352-5139 | |
dc.identifier.uri | https://cherry.chem.bg.ac.rs/handle/123456789/1749 | |
dc.description.abstract | A series of new pyridobenzazepine and pyridobenzothiepine derivatives was synthesized by Pd-catalyzed formation of C-N and C-S bonds. All synthesized compounds were tested for their in vitro antimicrobial activity. The pyridobenzazepine derivatives showed better antibacterial and antifungal activity than the corresponding dipyridoazepine analogue. Among the synthesized azepines, derivative 8 displayed potent activity against the tested bacteria (MIC ranged 39-78 mu g mL(-1)), while azepine 12 showed promising antifungal activity (MIC ranged 156-313 mu g mL(-1)). The synthesized thiepine derivatives exhibited weak antibacterial activity, but showed pronounced antifungal activity. | en |
dc.publisher | Serbian Chemical Soc, Belgrade | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172008/RS// | |
dc.relation | Serbian Academy of Sciences and Arts | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Journal of the Serbian Chemical Society | |
dc.subject | azepines | en |
dc.subject | thiepines | en |
dc.subject | heterocycles | en |
dc.subject | palladium | en |
dc.subject | antibacterials | en |
dc.subject | antifungal | en |
dc.title | Synthesis and antimicrobial activity of azepine and thiepine derivatives | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dcterms.abstract | Шолаја, Богдан A.; Бозиновиц, Нина; Новаковиц, Ирена; Рајациц, Сладана Костиц; Опсеница, Игор; | |
dc.citation.volume | 80 | |
dc.citation.issue | 7 | |
dc.citation.spage | 839 | |
dc.citation.epage | 852 | |
dc.identifier.wos | 000359326100001 | |
dc.identifier.doi | 10.2298/JSC150116013B | |
dc.citation.other | 80(7): 839-852 | |
dc.citation.rank | M23 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-84938924652 | |
dc.identifier.fulltext | https://cherry.chem.bg.ac.rs/bitstream/id/8820/1747.pdf |