Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential
Нема приказа
Аутори
Milovanović, IvanStanojković, Tatjana
Stajić, Mirjana
Brčeski, Ilija
Knežević, Aleksandar
Ćilerdžić, Jasmina
Vukojević, Jelena
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The aim of the study was an assessment of the antioxidant, antifungal and cytotoxic potentials of L. betulinus and T. hirsuta mycelia extracts and the effect of selenium on these activities. Extracts of L. betulinus were twice as efficient in DPPH center dot scavenging as those of T. hirsuta. The phenol content in Se-enriched L. betulinus extracts was higher than in non-enriched extracts, in contrast to the effect of Se-enrichment on T. hirsuta extracts, and a direct correlation between the amount and DPPH center dot scavenging effect was observed. Ethanol extracts exhibited fungistatic but not fungicidal activity against a range of micromycetes, and mycelium enrichment with selenium inhibited this effect. Although the extracts showed low cytotoxic activity against HeLa and LS174 cells, T. hirsuta extracts, especially those enriched with selenium, had better potential. L. betulinus extracts showed better antioxidant and antifungal activity than T. hirsuta extracts which were more activ...e cytotoxic agents. The presence of selenium stimulated antioxidant and cytotoxic, and inhibited antifungal activity in L. betulinus, while in T. hirsuta its effect was slight.
Кључне речи:
Biological activities / Lenzites betulinus / Trametes hirsuta / Mycelium extract / SeleniumИзвор:
Current Pharmaceutical Biotechnology, 2015, 16, 10, 920-926Издавач:
- Bentham Science Publ Ltd, Sharjah
Финансирање / пројекти:
- Карактеризација и примена метаболита гљива и утврђивање потенцијала нових биофунгицида (RS-MESTD-Basic Research (BR or ON)-173032)
DOI: 10.2174/1389201016666150618152531
ISSN: 1389-2010
PubMed: 26087835
WoS: 000359433600008
Scopus: 2-s2.0-84939817372
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Milovanović, Ivan AU - Stanojković, Tatjana AU - Stajić, Mirjana AU - Brčeski, Ilija AU - Knežević, Aleksandar AU - Ćilerdžić, Jasmina AU - Vukojević, Jelena PY - 2015 UR - https://cherry.chem.bg.ac.rs/handle/123456789/1752 AB - The aim of the study was an assessment of the antioxidant, antifungal and cytotoxic potentials of L. betulinus and T. hirsuta mycelia extracts and the effect of selenium on these activities. Extracts of L. betulinus were twice as efficient in DPPH center dot scavenging as those of T. hirsuta. The phenol content in Se-enriched L. betulinus extracts was higher than in non-enriched extracts, in contrast to the effect of Se-enrichment on T. hirsuta extracts, and a direct correlation between the amount and DPPH center dot scavenging effect was observed. Ethanol extracts exhibited fungistatic but not fungicidal activity against a range of micromycetes, and mycelium enrichment with selenium inhibited this effect. Although the extracts showed low cytotoxic activity against HeLa and LS174 cells, T. hirsuta extracts, especially those enriched with selenium, had better potential. L. betulinus extracts showed better antioxidant and antifungal activity than T. hirsuta extracts which were more active cytotoxic agents. The presence of selenium stimulated antioxidant and cytotoxic, and inhibited antifungal activity in L. betulinus, while in T. hirsuta its effect was slight. PB - Bentham Science Publ Ltd, Sharjah T2 - Current Pharmaceutical Biotechnology T1 - Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential VL - 16 IS - 10 SP - 920 EP - 926 DO - 10.2174/1389201016666150618152531 ER -
@article{ author = "Milovanović, Ivan and Stanojković, Tatjana and Stajić, Mirjana and Brčeski, Ilija and Knežević, Aleksandar and Ćilerdžić, Jasmina and Vukojević, Jelena", year = "2015", abstract = "The aim of the study was an assessment of the antioxidant, antifungal and cytotoxic potentials of L. betulinus and T. hirsuta mycelia extracts and the effect of selenium on these activities. Extracts of L. betulinus were twice as efficient in DPPH center dot scavenging as those of T. hirsuta. The phenol content in Se-enriched L. betulinus extracts was higher than in non-enriched extracts, in contrast to the effect of Se-enrichment on T. hirsuta extracts, and a direct correlation between the amount and DPPH center dot scavenging effect was observed. Ethanol extracts exhibited fungistatic but not fungicidal activity against a range of micromycetes, and mycelium enrichment with selenium inhibited this effect. Although the extracts showed low cytotoxic activity against HeLa and LS174 cells, T. hirsuta extracts, especially those enriched with selenium, had better potential. L. betulinus extracts showed better antioxidant and antifungal activity than T. hirsuta extracts which were more active cytotoxic agents. The presence of selenium stimulated antioxidant and cytotoxic, and inhibited antifungal activity in L. betulinus, while in T. hirsuta its effect was slight.", publisher = "Bentham Science Publ Ltd, Sharjah", journal = "Current Pharmaceutical Biotechnology", title = "Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential", volume = "16", number = "10", pages = "920-926", doi = "10.2174/1389201016666150618152531" }
Milovanović, I., Stanojković, T., Stajić, M., Brčeski, I., Knežević, A., Ćilerdžić, J.,& Vukojević, J.. (2015). Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential. in Current Pharmaceutical Biotechnology Bentham Science Publ Ltd, Sharjah., 16(10), 920-926. https://doi.org/10.2174/1389201016666150618152531
Milovanović I, Stanojković T, Stajić M, Brčeski I, Knežević A, Ćilerdžić J, Vukojević J. Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential. in Current Pharmaceutical Biotechnology. 2015;16(10):920-926. doi:10.2174/1389201016666150618152531 .
Milovanović, Ivan, Stanojković, Tatjana, Stajić, Mirjana, Brčeski, Ilija, Knežević, Aleksandar, Ćilerdžić, Jasmina, Vukojević, Jelena, "Effect of Selenium Enrichment of Lenzites betulinus and Trametes hirsuta Mycelia on Antioxidant, Antifungal and Cytostatics Potential" in Current Pharmaceutical Biotechnology, 16, no. 10 (2015):920-926, https://doi.org/10.2174/1389201016666150618152531 . .