Botox as the medication: Usage and abuse
Botoks - upotreba i zloupotreba
Apstrakt
Botulinum toxin is a neurotoxic protein, produced by bacterium Clostridium botulinum. This toxin specifically cleaves the SNAP-25 protein, required for vesicle fusion, that releases neurotransmitters from the axon endings (in particular acetylcholine). Although botulinum toxin is a lethal naturally occurring substance, it can be used as an effective and powerful medication, in the treatment of different types of spasms and dystonias, and also in cosmetics, but potential side effects do exist. Commercially it is known as BotoxR.
Botulinski toksin je izuzetno otrovna supstanca koju proizvodi bakterija Clostridum botulinum. Deluje na periferne nervne završetke, blokirajući oslobađanje neurotransmitera acetilholina. Interesantan je po tome što može da izazove oboljenje (botulizam), ali i da služi za lečenje mnogih bolesti (na primer, cervikalna distonija). U današnje vreme se koristi u različitim kozmetičkim tretmanima. Prekomerna upotreba izaziva neželjene efekte, a može dovesti do smrti.
Izvor:
Hemijski pregled, 2010, 51, 5, 118-120Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Lupović, Danijela AU - Konstantinović, Jelena M. PY - 2010 UR - https://cherry.chem.bg.ac.rs/handle/123456789/275 AB - Botulinum toxin is a neurotoxic protein, produced by bacterium Clostridium botulinum. This toxin specifically cleaves the SNAP-25 protein, required for vesicle fusion, that releases neurotransmitters from the axon endings (in particular acetylcholine). Although botulinum toxin is a lethal naturally occurring substance, it can be used as an effective and powerful medication, in the treatment of different types of spasms and dystonias, and also in cosmetics, but potential side effects do exist. Commercially it is known as BotoxR. AB - Botulinski toksin je izuzetno otrovna supstanca koju proizvodi bakterija Clostridum botulinum. Deluje na periferne nervne završetke, blokirajući oslobađanje neurotransmitera acetilholina. Interesantan je po tome što može da izazove oboljenje (botulizam), ali i da služi za lečenje mnogih bolesti (na primer, cervikalna distonija). U današnje vreme se koristi u različitim kozmetičkim tretmanima. Prekomerna upotreba izaziva neželjene efekte, a može dovesti do smrti. T2 - Hemijski pregled T1 - Botox as the medication: Usage and abuse T1 - Botoks - upotreba i zloupotreba VL - 51 IS - 5 SP - 118 EP - 120 UR - https://hdl.handle.net/21.15107/rcub_cherry_275 ER -
@article{ author = "Lupović, Danijela and Konstantinović, Jelena M.", year = "2010", abstract = "Botulinum toxin is a neurotoxic protein, produced by bacterium Clostridium botulinum. This toxin specifically cleaves the SNAP-25 protein, required for vesicle fusion, that releases neurotransmitters from the axon endings (in particular acetylcholine). Although botulinum toxin is a lethal naturally occurring substance, it can be used as an effective and powerful medication, in the treatment of different types of spasms and dystonias, and also in cosmetics, but potential side effects do exist. Commercially it is known as BotoxR., Botulinski toksin je izuzetno otrovna supstanca koju proizvodi bakterija Clostridum botulinum. Deluje na periferne nervne završetke, blokirajući oslobađanje neurotransmitera acetilholina. Interesantan je po tome što može da izazove oboljenje (botulizam), ali i da služi za lečenje mnogih bolesti (na primer, cervikalna distonija). U današnje vreme se koristi u različitim kozmetičkim tretmanima. Prekomerna upotreba izaziva neželjene efekte, a može dovesti do smrti.", journal = "Hemijski pregled", title = "Botox as the medication: Usage and abuse, Botoks - upotreba i zloupotreba", volume = "51", number = "5", pages = "118-120", url = "https://hdl.handle.net/21.15107/rcub_cherry_275" }
Lupović, D.,& Konstantinović, J. M.. (2010). Botox as the medication: Usage and abuse. in Hemijski pregled, 51(5), 118-120. https://hdl.handle.net/21.15107/rcub_cherry_275
Lupović D, Konstantinović JM. Botox as the medication: Usage and abuse. in Hemijski pregled. 2010;51(5):118-120. https://hdl.handle.net/21.15107/rcub_cherry_275 .
Lupović, Danijela, Konstantinović, Jelena M., "Botox as the medication: Usage and abuse" in Hemijski pregled, 51, no. 5 (2010):118-120, https://hdl.handle.net/21.15107/rcub_cherry_275 .