Facile synthesis of hydrophilic polymer-capped upconverting NaYF4:Yb,Er particles
2017
Authors
Dinić, IvanaMančić, Lidija
Nikolić, Marko G.
Radulović, Katarina
Marinković, Bojan A.
Milošević, Olivera B.
Contributors
Mitić, Vojislav V.Mančić, Lidija
Obradović, Nina
Conference object (Published version)
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Over the last decade, solvothermal decomposition of organometallic compounds has been indicated as one of the most convenient method for the synthesis of monodisperse lanthanide doped upconverting fluorides. Due to their hydrophobic nature such particles could not be used for a conjugation of the molecular targeting agents which is necessary for optical imaging of biological tissues. In this work, hydrophilic NaYF4:Yb,Er (17 mol% Yb; 3mol% Er) nanoparticles were synthesized by facile one-pot hydrothermal synthesis performed with a help of chitosan (CS) and poly(acrylic acid) (PAA). Obtained powders were analyzed by X-ray powder diffraction (XRPD), field emission scanning electron microscopy (FESEM), Fourier transform infrared (FTIR) and photoluminescence (PL) spectroscopy. The obtained results implied that particle size, shape and surface characteristics are dependent on the polymer choice. Although both powders crystallize in the same crystal arrangement (cubic, Fm-3m) more intense re...d emission, assigned to the Er3+ 4F9/2 → 4I15/2 electronic transitions, characterize spherical NaYF4:Yb,Er@CS particles. To asses a biological safety of their use, viability of the human gingival fibroblasts (HFG) was additionally tested by a colorimetric MTT assay.
Keywords:
organometallic compounds / solvothermal decomposition / NaYF4:Yb,Er / upconversionSource:
Serbian Ceramic Society Conference Advanced Ceramics and Application VI: Program and the Book of Abstracts, 2017Publisher:
- Belgrade : Serbian Ceramic Society
Funding / projects:
- Rational design and synthesis of biologically active and coordination compounds and functional materials, relevant for (bio)nanotechnology (RS-MESTD-Basic Research (BR or ON)-172035)
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Hemijski fakultet / Faculty of ChemistryTY - CONF AU - Dinić, Ivana AU - Mančić, Lidija AU - Nikolić, Marko G. AU - Radulović, Katarina AU - Marinković, Bojan A. AU - Milošević, Olivera B. PY - 2017 UR - http://dais.sanu.ac.rs/123456789/2361 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2772 AB - Over the last decade, solvothermal decomposition of organometallic compounds has been indicated as one of the most convenient method for the synthesis of monodisperse lanthanide doped upconverting fluorides. Due to their hydrophobic nature such particles could not be used for a conjugation of the molecular targeting agents which is necessary for optical imaging of biological tissues. In this work, hydrophilic NaYF4:Yb,Er (17 mol% Yb; 3mol% Er) nanoparticles were synthesized by facile one-pot hydrothermal synthesis performed with a help of chitosan (CS) and poly(acrylic acid) (PAA). Obtained powders were analyzed by X-ray powder diffraction (XRPD), field emission scanning electron microscopy (FESEM), Fourier transform infrared (FTIR) and photoluminescence (PL) spectroscopy. The obtained results implied that particle size, shape and surface characteristics are dependent on the polymer choice. Although both powders crystallize in the same crystal arrangement (cubic, Fm-3m) more intense red emission, assigned to the Er3+ 4F9/2 → 4I15/2 electronic transitions, characterize spherical NaYF4:Yb,Er@CS particles. To asses a biological safety of their use, viability of the human gingival fibroblasts (HFG) was additionally tested by a colorimetric MTT assay. PB - Belgrade : Serbian Ceramic Society C3 - Serbian Ceramic Society Conference Advanced Ceramics and Application VI: Program and the Book of Abstracts T1 - Facile synthesis of hydrophilic polymer-capped upconverting NaYF4:Yb,Er particles UR - https://hdl.handle.net/21.15107/rcub_cherry_2772 ER -
@conference{ editor = "Mitić, Vojislav V., Mančić, Lidija, Obradović, Nina", author = "Dinić, Ivana and Mančić, Lidija and Nikolić, Marko G. and Radulović, Katarina and Marinković, Bojan A. and Milošević, Olivera B.", year = "2017", abstract = "Over the last decade, solvothermal decomposition of organometallic compounds has been indicated as one of the most convenient method for the synthesis of monodisperse lanthanide doped upconverting fluorides. Due to their hydrophobic nature such particles could not be used for a conjugation of the molecular targeting agents which is necessary for optical imaging of biological tissues. In this work, hydrophilic NaYF4:Yb,Er (17 mol% Yb; 3mol% Er) nanoparticles were synthesized by facile one-pot hydrothermal synthesis performed with a help of chitosan (CS) and poly(acrylic acid) (PAA). Obtained powders were analyzed by X-ray powder diffraction (XRPD), field emission scanning electron microscopy (FESEM), Fourier transform infrared (FTIR) and photoluminescence (PL) spectroscopy. The obtained results implied that particle size, shape and surface characteristics are dependent on the polymer choice. Although both powders crystallize in the same crystal arrangement (cubic, Fm-3m) more intense red emission, assigned to the Er3+ 4F9/2 → 4I15/2 electronic transitions, characterize spherical NaYF4:Yb,Er@CS particles. To asses a biological safety of their use, viability of the human gingival fibroblasts (HFG) was additionally tested by a colorimetric MTT assay.", publisher = "Belgrade : Serbian Ceramic Society", journal = "Serbian Ceramic Society Conference Advanced Ceramics and Application VI: Program and the Book of Abstracts", title = "Facile synthesis of hydrophilic polymer-capped upconverting NaYF4:Yb,Er particles", url = "https://hdl.handle.net/21.15107/rcub_cherry_2772" }
Mitić, V. V., Mančić, L., Obradović, N., Dinić, I., Mančić, L., Nikolić, M. G., Radulović, K., Marinković, B. A.,& Milošević, O. B.. (2017). Facile synthesis of hydrophilic polymer-capped upconverting NaYF4:Yb,Er particles. in Serbian Ceramic Society Conference Advanced Ceramics and Application VI: Program and the Book of Abstracts Belgrade : Serbian Ceramic Society.. https://hdl.handle.net/21.15107/rcub_cherry_2772
Mitić VV, Mančić L, Obradović N, Dinić I, Mančić L, Nikolić MG, Radulović K, Marinković BA, Milošević OB. Facile synthesis of hydrophilic polymer-capped upconverting NaYF4:Yb,Er particles. in Serbian Ceramic Society Conference Advanced Ceramics and Application VI: Program and the Book of Abstracts. 2017;. https://hdl.handle.net/21.15107/rcub_cherry_2772 .
Mitić, Vojislav V., Mančić, Lidija, Obradović, Nina, Dinić, Ivana, Mančić, Lidija, Nikolić, Marko G., Radulović, Katarina, Marinković, Bojan A., Milošević, Olivera B., "Facile synthesis of hydrophilic polymer-capped upconverting NaYF4:Yb,Er particles" in Serbian Ceramic Society Conference Advanced Ceramics and Application VI: Program and the Book of Abstracts (2017), https://hdl.handle.net/21.15107/rcub_cherry_2772 .