Lanthanide doped hydroxyapatite for multimodal imaging
Autori
Dinić, IvanaVuković, Marina
Ignjatović, Nenad
Stojanović, Zoran
Škapin, Srečo
Veselinović, Ljiljana M.
Mančić, Lidija
Ostala autorstva
Mitić, Vojislav V.Mančić, Lidija
Obradović, Nina
Konferencijski prilog (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Lantanide dual-doped hydroxyapatite (HaP:Ln) is currently the subject of numerous studies in reconstructive medicine. Designed in form of hybrid nanoparticles which have magnetic and luminescent properties HaP:Ln (where Ln=Gd/Eu or Gd/Yb/Tm) is capable to enhance signal detection. Beside it, due biodegradable properties it is suitable for use in bone tissue engineering and target drug delivery. For such a promising approach, doping of a HAp matrix is performed with Gd/Eu and Gd/Yb/Tm during hydrothermal synthesis using EDTA as chelating agent. Morphological and structural characteristics of the particles were obtained using X-ray powder diffraction (XRPD), scanning and transmission electron microscopy (SEM/TEM), energy dispersive X-ray spectroscopy (EDX), Fourier Transform Infrared (FTIR) and photoluminescence (PL). The results show that needle-like nano- or micro- particles were obtained in all systems. Their phase composition and uniform distribution of dopants were confirmed by the ...structural refinement of the XRPD data and luminescence response from Eu and Tb (λex = 370, 394 and 977 nm).
Ključne reči:
lantanide / doping / hydroxyapatite / multimodal imagingIzvor:
Program and the Book of Abstracts / Serbian Ceramic Society Conference Advanced Ceramics and Application VII : New Frontiers in Multifunctional Material Science and Processing, Serbia, Belgrade, 17-19 September 2018, 2018, 71-71Izdavač:
- Belgrade : Serbian Ceramic Society
Finansiranje / projekti:
- Racionalni dizajn i sinteza biološki aktivnih i koordinacionih jedinjenja i funkcionalnih materijala, relevantnih u (bio)nanotehnologiji (RS-MESTD-Basic Research (BR or ON)-172035)
- Molekularno dizajniranje nanočestica kontrolisanih morfoloških i fizičko-hemijskih karakteristika i funkcionalnih materijala na njihovoj osnovi (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45004)
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - CONF AU - Dinić, Ivana AU - Vuković, Marina AU - Ignjatović, Nenad AU - Stojanović, Zoran AU - Škapin, Srečo AU - Veselinović, Ljiljana M. AU - Mančić, Lidija PY - 2018 UR - http://dais.sanu.ac.rs/123456789/4118 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2776 AB - Lantanide dual-doped hydroxyapatite (HaP:Ln) is currently the subject of numerous studies in reconstructive medicine. Designed in form of hybrid nanoparticles which have magnetic and luminescent properties HaP:Ln (where Ln=Gd/Eu or Gd/Yb/Tm) is capable to enhance signal detection. Beside it, due biodegradable properties it is suitable for use in bone tissue engineering and target drug delivery. For such a promising approach, doping of a HAp matrix is performed with Gd/Eu and Gd/Yb/Tm during hydrothermal synthesis using EDTA as chelating agent. Morphological and structural characteristics of the particles were obtained using X-ray powder diffraction (XRPD), scanning and transmission electron microscopy (SEM/TEM), energy dispersive X-ray spectroscopy (EDX), Fourier Transform Infrared (FTIR) and photoluminescence (PL). The results show that needle-like nano- or micro- particles were obtained in all systems. Their phase composition and uniform distribution of dopants were confirmed by the structural refinement of the XRPD data and luminescence response from Eu and Tb (λex = 370, 394 and 977 nm). PB - Belgrade : Serbian Ceramic Society C3 - Program and the Book of Abstracts / Serbian Ceramic Society Conference Advanced Ceramics and Application VII : New Frontiers in Multifunctional Material Science and Processing, Serbia, Belgrade, 17-19 September 2018 T1 - Lanthanide doped hydroxyapatite for multimodal imaging SP - 71 EP - 71 UR - https://hdl.handle.net/21.15107/rcub_cherry_2776 ER -
@conference{ author = "Dinić, Ivana and Vuković, Marina and Ignjatović, Nenad and Stojanović, Zoran and Škapin, Srečo and Veselinović, Ljiljana M. and Mančić, Lidija", year = "2018", abstract = "Lantanide dual-doped hydroxyapatite (HaP:Ln) is currently the subject of numerous studies in reconstructive medicine. Designed in form of hybrid nanoparticles which have magnetic and luminescent properties HaP:Ln (where Ln=Gd/Eu or Gd/Yb/Tm) is capable to enhance signal detection. Beside it, due biodegradable properties it is suitable for use in bone tissue engineering and target drug delivery. For such a promising approach, doping of a HAp matrix is performed with Gd/Eu and Gd/Yb/Tm during hydrothermal synthesis using EDTA as chelating agent. Morphological and structural characteristics of the particles were obtained using X-ray powder diffraction (XRPD), scanning and transmission electron microscopy (SEM/TEM), energy dispersive X-ray spectroscopy (EDX), Fourier Transform Infrared (FTIR) and photoluminescence (PL). The results show that needle-like nano- or micro- particles were obtained in all systems. Their phase composition and uniform distribution of dopants were confirmed by the structural refinement of the XRPD data and luminescence response from Eu and Tb (λex = 370, 394 and 977 nm).", publisher = "Belgrade : Serbian Ceramic Society", journal = "Program and the Book of Abstracts / Serbian Ceramic Society Conference Advanced Ceramics and Application VII : New Frontiers in Multifunctional Material Science and Processing, Serbia, Belgrade, 17-19 September 2018", title = "Lanthanide doped hydroxyapatite for multimodal imaging", pages = "71-71", url = "https://hdl.handle.net/21.15107/rcub_cherry_2776" }
Dinić, I., Vuković, M., Ignjatović, N., Stojanović, Z., Škapin, S., Veselinović, L. M.,& Mančić, L.. (2018). Lanthanide doped hydroxyapatite for multimodal imaging. in Program and the Book of Abstracts / Serbian Ceramic Society Conference Advanced Ceramics and Application VII : New Frontiers in Multifunctional Material Science and Processing, Serbia, Belgrade, 17-19 September 2018 Belgrade : Serbian Ceramic Society., 71-71. https://hdl.handle.net/21.15107/rcub_cherry_2776
Dinić I, Vuković M, Ignjatović N, Stojanović Z, Škapin S, Veselinović LM, Mančić L. Lanthanide doped hydroxyapatite for multimodal imaging. in Program and the Book of Abstracts / Serbian Ceramic Society Conference Advanced Ceramics and Application VII : New Frontiers in Multifunctional Material Science and Processing, Serbia, Belgrade, 17-19 September 2018. 2018;:71-71. https://hdl.handle.net/21.15107/rcub_cherry_2776 .
Dinić, Ivana, Vuković, Marina, Ignjatović, Nenad, Stojanović, Zoran, Škapin, Srečo, Veselinović, Ljiljana M., Mančić, Lidija, "Lanthanide doped hydroxyapatite for multimodal imaging" in Program and the Book of Abstracts / Serbian Ceramic Society Conference Advanced Ceramics and Application VII : New Frontiers in Multifunctional Material Science and Processing, Serbia, Belgrade, 17-19 September 2018 (2018):71-71, https://hdl.handle.net/21.15107/rcub_cherry_2776 .