An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode
Аутори
Šovrc, ĽubomírStrežova, Ivana
Kianicková, Kristína
Stanković, Dalibor
Otrisal, Pavel
Samphao, Anchalee
Чланак у часопису (Рецензирана верзија)
Метаподаци
Приказ свих података о документуАпстракт
Herein, an advanced electroanalytical approach for the determination of ibuprofen based on the use of a bare and electrochemically untreated boron-doped diamond electrode is presented. Cyclic voltammetric study revealed that the electrode reaction of the analyte was manifested by the presence of well-shaped irreversible and diffusion-driven oxidation peak at very high potential (+1.75 V vs. Ag/AgCl/3 mol L-1 KCl reference electrode) in 1 mol L-1 perchloric acid. After optimization of experimental conditions, the peak current of ibuprofen was proportionally linear from 9.49 x 10(-7) to 6.69 x 10(-5) mol L-1 providing both differential pulse (DPV) and square-wave voltammetric (SWV) techniques, respectively. The elaborated electroanalytical protocol rendered low detection limits of 4.1 x 10(-7) and 9.3 x 10(-7 )mol L-1 in association with favourable intra day repeatability (relative standard deviation of 3.6 and 4.6%) using DPV and SWV procedures, respectively. The effect of interfering c...ompounds such as ascorbic acid, dopamine, caffeine, uric acid and glucose on the current response of ibuprofen was explored in details. The usefulness of the proposed approach was verified in the analysis of a variety of commercial brands of pharmaceuticals and spiked human urine samples with the significant range of recovery percentages (for pharmaceuticals 99.8-107.5% and 99.8-105.0% by DPV and SWV, for urine 95-107% and 97-103% by DPV and SWV). Taking these features into account, the developed protocol may be exploited as a novel, simple and efficient tool in drug quality control analysis and analysis of biological samples. In addition, a bare and electrochemically untreated boron-doped diamond electrode may be applied as a progressive electrochemical sensor and helpful alternative to previously utilized electrochemical platforms in this field.
Кључне речи:
Ibuprofen / Boron-doped diamond electrode / Differential pulse voltammetry / Square-wave voltammetry / Pharmaceutical dosageИзвор:
Journal of Electroanalytical Chemistry, 2018, 822, 144-152Издавач:
- Elsevier Science Sa, Lausanne
Финансирање / пројекти:
- Примена унапређених оксидационих процеса и наноструктурисаних оксидних материјала за уклањање загађивача из животне средине, развој и оптимизација инструменталних техника за праћење ефикасности (RS-MESTD-Basic Research (BR or ON)-172030)
- Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials (EU-FP7-621375)
- Grant Agency of the Slovak Republic [1/0489/16]
Напомена:
- This is the peer-reviewed version of the following article: Švorc, Ľ.; Strežová, I.; Kianičková, K.; Stanković, D. M.; Otřísal, P.; Samphao, A. An Advanced Approach for Electrochemical Sensing of Ibuprofen in Pharmaceuticals and Human Urine Samples Using a Bare Boron-Doped Diamond Electrode. Journal of Electroanalytical Chemistry 2018, 822, 144–152. https://doi.org/10.1016/j.jelechem.2018.05.026
DOI: 10.1016/j.jelechem.2018.05.026
ISSN: 1572-6657
WoS: 000438005300018
Scopus: 2-s2.0-85047245918
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Šovrc, Ľubomír AU - Strežova, Ivana AU - Kianicková, Kristína AU - Stanković, Dalibor AU - Otrisal, Pavel AU - Samphao, Anchalee PY - 2018 UR - https://cherry.chem.bg.ac.rs/handle/123456789/2938 AB - Herein, an advanced electroanalytical approach for the determination of ibuprofen based on the use of a bare and electrochemically untreated boron-doped diamond electrode is presented. Cyclic voltammetric study revealed that the electrode reaction of the analyte was manifested by the presence of well-shaped irreversible and diffusion-driven oxidation peak at very high potential (+1.75 V vs. Ag/AgCl/3 mol L-1 KCl reference electrode) in 1 mol L-1 perchloric acid. After optimization of experimental conditions, the peak current of ibuprofen was proportionally linear from 9.49 x 10(-7) to 6.69 x 10(-5) mol L-1 providing both differential pulse (DPV) and square-wave voltammetric (SWV) techniques, respectively. The elaborated electroanalytical protocol rendered low detection limits of 4.1 x 10(-7) and 9.3 x 10(-7 )mol L-1 in association with favourable intra day repeatability (relative standard deviation of 3.6 and 4.6%) using DPV and SWV procedures, respectively. The effect of interfering compounds such as ascorbic acid, dopamine, caffeine, uric acid and glucose on the current response of ibuprofen was explored in details. The usefulness of the proposed approach was verified in the analysis of a variety of commercial brands of pharmaceuticals and spiked human urine samples with the significant range of recovery percentages (for pharmaceuticals 99.8-107.5% and 99.8-105.0% by DPV and SWV, for urine 95-107% and 97-103% by DPV and SWV). Taking these features into account, the developed protocol may be exploited as a novel, simple and efficient tool in drug quality control analysis and analysis of biological samples. In addition, a bare and electrochemically untreated boron-doped diamond electrode may be applied as a progressive electrochemical sensor and helpful alternative to previously utilized electrochemical platforms in this field. PB - Elsevier Science Sa, Lausanne T2 - Journal of Electroanalytical Chemistry T1 - An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode VL - 822 SP - 144 EP - 152 DO - 10.1016/j.jelechem.2018.05.026 ER -
@article{ author = "Šovrc, Ľubomír and Strežova, Ivana and Kianicková, Kristína and Stanković, Dalibor and Otrisal, Pavel and Samphao, Anchalee", year = "2018", abstract = "Herein, an advanced electroanalytical approach for the determination of ibuprofen based on the use of a bare and electrochemically untreated boron-doped diamond electrode is presented. Cyclic voltammetric study revealed that the electrode reaction of the analyte was manifested by the presence of well-shaped irreversible and diffusion-driven oxidation peak at very high potential (+1.75 V vs. Ag/AgCl/3 mol L-1 KCl reference electrode) in 1 mol L-1 perchloric acid. After optimization of experimental conditions, the peak current of ibuprofen was proportionally linear from 9.49 x 10(-7) to 6.69 x 10(-5) mol L-1 providing both differential pulse (DPV) and square-wave voltammetric (SWV) techniques, respectively. The elaborated electroanalytical protocol rendered low detection limits of 4.1 x 10(-7) and 9.3 x 10(-7 )mol L-1 in association with favourable intra day repeatability (relative standard deviation of 3.6 and 4.6%) using DPV and SWV procedures, respectively. The effect of interfering compounds such as ascorbic acid, dopamine, caffeine, uric acid and glucose on the current response of ibuprofen was explored in details. The usefulness of the proposed approach was verified in the analysis of a variety of commercial brands of pharmaceuticals and spiked human urine samples with the significant range of recovery percentages (for pharmaceuticals 99.8-107.5% and 99.8-105.0% by DPV and SWV, for urine 95-107% and 97-103% by DPV and SWV). Taking these features into account, the developed protocol may be exploited as a novel, simple and efficient tool in drug quality control analysis and analysis of biological samples. In addition, a bare and electrochemically untreated boron-doped diamond electrode may be applied as a progressive electrochemical sensor and helpful alternative to previously utilized electrochemical platforms in this field.", publisher = "Elsevier Science Sa, Lausanne", journal = "Journal of Electroanalytical Chemistry", title = "An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode", volume = "822", pages = "144-152", doi = "10.1016/j.jelechem.2018.05.026" }
Šovrc, Ľ., Strežova, I., Kianicková, K., Stanković, D., Otrisal, P.,& Samphao, A.. (2018). An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode. in Journal of Electroanalytical Chemistry Elsevier Science Sa, Lausanne., 822, 144-152. https://doi.org/10.1016/j.jelechem.2018.05.026
Šovrc Ľ, Strežova I, Kianicková K, Stanković D, Otrisal P, Samphao A. An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode. in Journal of Electroanalytical Chemistry. 2018;822:144-152. doi:10.1016/j.jelechem.2018.05.026 .
Šovrc, Ľubomír, Strežova, Ivana, Kianicková, Kristína, Stanković, Dalibor, Otrisal, Pavel, Samphao, Anchalee, "An advanced approach for electrochemical sensing of ibuprofen in pharmaceuticals and human urine samples using a bare boron-doped diamond electrode" in Journal of Electroanalytical Chemistry, 822 (2018):144-152, https://doi.org/10.1016/j.jelechem.2018.05.026 . .