Collegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparations
Članak u časopisu (Recenzirana verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Ficus carica, the common fig has been widely used for centuries for medicine as well as food. Fig latex is used for the treatments of cancer, inflammatory diseases, bacterial and gastrointestinal nematode infections, warts and skin diseases. The aim of the study was to investigate if some of the fig latex applications could be attributed to collagenase activity. The usage of figs in the Western Balkans indicated that the latex of unripe fruits is often used for treatments that could involve remodeling of connective tissue. Collagenase activity in fig latices collected in spring was twice as high as the one detected in summer. Collagenase improved diffusion of low-molecular-weight model molecule through the gelatin hydrogel. Fig latex collagenase was stable during boiling and in the simulated gastric conditions for up to 1 h. The presence of fig latex collagenase in traditional medicine preparations could increase treatment efficacy by hydrolyzing collagen present in extracellular matri...x and facilitating the penetration of active molecules through the connective tissue. (C) 2016 Elsevier GmbH. All rights reserved.
Ključne reči:
West Balkan / Fig latex / Collagenase / Ficus carica / Extracellular matrixIzvor:
Journal of Herbal Medicine, 2016, 6, 2, 73-78Izdavač:
- Elsevier Gmbh, Urban & Fischer Verlag, Jena
Finansiranje / projekti:
- Alergeni, antitela, enzimi i mali fiziološki značajni molekuli: dizajn, struktura, funkcija i značaj (RS-MESTD-Basic Research (BR or ON)-172049)
Napomena:
- This is peer-reviewed version of the following article: Raskovic, B. G.; Polovic, N. D. Collegenase Activity in Fig Latex Could Contribute to Its Efficacy in Ethnomedicinal Preparations. Journal of Herbal Medicine 2016, 6 (2), 73–78. https://doi.org/10.1016/j.hermed.2016.03.002
DOI: 10.1016/j.hermed.2016.03.002
ISSN: 2210-8033
WoS: 000378670400004
Scopus: 2-s2.0-84964355271
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Rašković, Brankica AU - Polović, Natalija PY - 2016 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3413 AB - Ficus carica, the common fig has been widely used for centuries for medicine as well as food. Fig latex is used for the treatments of cancer, inflammatory diseases, bacterial and gastrointestinal nematode infections, warts and skin diseases. The aim of the study was to investigate if some of the fig latex applications could be attributed to collagenase activity. The usage of figs in the Western Balkans indicated that the latex of unripe fruits is often used for treatments that could involve remodeling of connective tissue. Collagenase activity in fig latices collected in spring was twice as high as the one detected in summer. Collagenase improved diffusion of low-molecular-weight model molecule through the gelatin hydrogel. Fig latex collagenase was stable during boiling and in the simulated gastric conditions for up to 1 h. The presence of fig latex collagenase in traditional medicine preparations could increase treatment efficacy by hydrolyzing collagen present in extracellular matrix and facilitating the penetration of active molecules through the connective tissue. (C) 2016 Elsevier GmbH. All rights reserved. PB - Elsevier Gmbh, Urban & Fischer Verlag, Jena T2 - Journal of Herbal Medicine T1 - Collegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparations VL - 6 IS - 2 SP - 73 EP - 78 DO - 10.1016/j.hermed.2016.03.002 ER -
@article{ author = "Rašković, Brankica and Polović, Natalija", year = "2016", abstract = "Ficus carica, the common fig has been widely used for centuries for medicine as well as food. Fig latex is used for the treatments of cancer, inflammatory diseases, bacterial and gastrointestinal nematode infections, warts and skin diseases. The aim of the study was to investigate if some of the fig latex applications could be attributed to collagenase activity. The usage of figs in the Western Balkans indicated that the latex of unripe fruits is often used for treatments that could involve remodeling of connective tissue. Collagenase activity in fig latices collected in spring was twice as high as the one detected in summer. Collagenase improved diffusion of low-molecular-weight model molecule through the gelatin hydrogel. Fig latex collagenase was stable during boiling and in the simulated gastric conditions for up to 1 h. The presence of fig latex collagenase in traditional medicine preparations could increase treatment efficacy by hydrolyzing collagen present in extracellular matrix and facilitating the penetration of active molecules through the connective tissue. (C) 2016 Elsevier GmbH. All rights reserved.", publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena", journal = "Journal of Herbal Medicine", title = "Collegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparations", volume = "6", number = "2", pages = "73-78", doi = "10.1016/j.hermed.2016.03.002" }
Rašković, B.,& Polović, N.. (2016). Collegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparations. in Journal of Herbal Medicine Elsevier Gmbh, Urban & Fischer Verlag, Jena., 6(2), 73-78. https://doi.org/10.1016/j.hermed.2016.03.002
Rašković B, Polović N. Collegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparations. in Journal of Herbal Medicine. 2016;6(2):73-78. doi:10.1016/j.hermed.2016.03.002 .
Rašković, Brankica, Polović, Natalija, "Collegenase activity in fig latex could contribute to its efficacy in ethnomedicinal preparations" in Journal of Herbal Medicine, 6, no. 2 (2016):73-78, https://doi.org/10.1016/j.hermed.2016.03.002 . .