Thin-layer chromatography in medicinal chemistry
Samo za registrovane korisnike
2019
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Among widely used chromatographic methods modern thin-layer chromatography is not only the simplest to perform but is also considered as respectable analytical method in various phases of drug discovery and development processes such as monitoring of synthesis, identification of bioactive substances from various natural sources and their isolation and purification, determination of lipophilicity and other physico-chemical parameters, quantitative structure-activity relationship studies, bioautography, as well as qualitative and quantitative analysis of drugs and their metabolites. An overview of recently published papers dealing with application of thin-layer chromatography in medicinal chemistry is presented.
Ključne reči:
ADMET parameters / bioautography / lipophilicity / TLC in drug developmentIzvor:
Journal of Liquid Chromatography and Related Technologies, 2019, 42, 9-10, 238-248Izdavač:
- Taylor and Francis Inc.
Finansiranje / projekti:
- Sinteza aminohinolina i njihovih derivata kao antimalarika i inhibitora botulinum neurotoksina A (RS-MESTD-Basic Research (BR or ON)-172008)
- Korelacija strukture i osobina prirodnih i sintetičkih molekula i njihovih kompleksa sa metalima (RS-MESTD-Basic Research (BR or ON)-172017)
DOI: 10.1080/10826076.2019.1585615
ISSN: 1082-6076
WoS: 000465830800001
Scopus: 2-s2.0-85064253810
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Šegan, Sandra B. AU - Opsenica, Dejan M. AU - Milojković-Opsenica, Dušanka PY - 2019 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3686 AB - Among widely used chromatographic methods modern thin-layer chromatography is not only the simplest to perform but is also considered as respectable analytical method in various phases of drug discovery and development processes such as monitoring of synthesis, identification of bioactive substances from various natural sources and their isolation and purification, determination of lipophilicity and other physico-chemical parameters, quantitative structure-activity relationship studies, bioautography, as well as qualitative and quantitative analysis of drugs and their metabolites. An overview of recently published papers dealing with application of thin-layer chromatography in medicinal chemistry is presented. PB - Taylor and Francis Inc. T2 - Journal of Liquid Chromatography and Related Technologies T1 - Thin-layer chromatography in medicinal chemistry VL - 42 IS - 9-10 SP - 238 EP - 248 DO - 10.1080/10826076.2019.1585615 ER -
@article{ author = "Šegan, Sandra B. and Opsenica, Dejan M. and Milojković-Opsenica, Dušanka", year = "2019", abstract = "Among widely used chromatographic methods modern thin-layer chromatography is not only the simplest to perform but is also considered as respectable analytical method in various phases of drug discovery and development processes such as monitoring of synthesis, identification of bioactive substances from various natural sources and their isolation and purification, determination of lipophilicity and other physico-chemical parameters, quantitative structure-activity relationship studies, bioautography, as well as qualitative and quantitative analysis of drugs and their metabolites. An overview of recently published papers dealing with application of thin-layer chromatography in medicinal chemistry is presented.", publisher = "Taylor and Francis Inc.", journal = "Journal of Liquid Chromatography and Related Technologies", title = "Thin-layer chromatography in medicinal chemistry", volume = "42", number = "9-10", pages = "238-248", doi = "10.1080/10826076.2019.1585615" }
Šegan, S. B., Opsenica, D. M.,& Milojković-Opsenica, D.. (2019). Thin-layer chromatography in medicinal chemistry. in Journal of Liquid Chromatography and Related Technologies Taylor and Francis Inc.., 42(9-10), 238-248. https://doi.org/10.1080/10826076.2019.1585615
Šegan SB, Opsenica DM, Milojković-Opsenica D. Thin-layer chromatography in medicinal chemistry. in Journal of Liquid Chromatography and Related Technologies. 2019;42(9-10):238-248. doi:10.1080/10826076.2019.1585615 .
Šegan, Sandra B., Opsenica, Dejan M., Milojković-Opsenica, Dušanka, "Thin-layer chromatography in medicinal chemistry" in Journal of Liquid Chromatography and Related Technologies, 42, no. 9-10 (2019):238-248, https://doi.org/10.1080/10826076.2019.1585615 . .