Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations
Samo za registrovane korisnike
2020
Autori
Mészáros, János P.Geisler, Heiko
Poljarević, Jelena
Roller, Alexander
Legina, Maria S.
Hejl, Michaela
Jakupec, Michael A.
Keppler, Bernhard K.
Kandioller, Wolfgang
Enyedy, Éva A.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and solution phase by analytical, spectroscopic, electrochemical and single crystal X-ray diffraction techniques. Comparative studies revealed the influence of the respective metal center (Ru, Os, Rh), leaving group (Cl, Br, I) and arene (p-cymene, toluene, pentamethylcyclopentadienyl), as well as the naphthoquinone ligand on the structural properties and solution speciation. Additionally, cytotoxicity was tested in SW480, CH1/PA-1 and A549 human cancer cell lines showing a broad range of IC50 values.
Ključne reči:
Cytotoxicity / Half-sandwich complexes / Natural ligands / Solution stability / X-ray crystal structuresIzvor:
Journal of Organometallic Chemistry, 2020, 907Izdavač:
- Elsevier
Finansiranje / projekti:
- GINOP-2.3.2-15- 2016-00038
- FK 124240
- FIKP program TUDFO/47138e1/2019- ITM. J.P. M
- ÚNKP-19-3 National Excellence Program of the Ministry for Innovation and Technology
Napomena:
- Supplementary material: http://cherry.chem.bg.ac.rs/handle/123456789/3805
DOI: 10.1016/j.jorganchem.2019.121070
ISSN: 0022-328X
WoS: 000506406600004
Scopus: 2-s2.0-85076311922
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Mészáros, János P. AU - Geisler, Heiko AU - Poljarević, Jelena AU - Roller, Alexander AU - Legina, Maria S. AU - Hejl, Michaela AU - Jakupec, Michael A. AU - Keppler, Bernhard K. AU - Kandioller, Wolfgang AU - Enyedy, Éva A. PY - 2020 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3804 AB - Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and solution phase by analytical, spectroscopic, electrochemical and single crystal X-ray diffraction techniques. Comparative studies revealed the influence of the respective metal center (Ru, Os, Rh), leaving group (Cl, Br, I) and arene (p-cymene, toluene, pentamethylcyclopentadienyl), as well as the naphthoquinone ligand on the structural properties and solution speciation. Additionally, cytotoxicity was tested in SW480, CH1/PA-1 and A549 human cancer cell lines showing a broad range of IC50 values. PB - Elsevier T2 - Journal of Organometallic Chemistry T1 - Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations VL - 907 DO - 10.1016/j.jorganchem.2019.121070 ER -
@article{ author = "Mészáros, János P. and Geisler, Heiko and Poljarević, Jelena and Roller, Alexander and Legina, Maria S. and Hejl, Michaela and Jakupec, Michael A. and Keppler, Bernhard K. and Kandioller, Wolfgang and Enyedy, Éva A.", year = "2020", abstract = "Half-sandwich organometallic complexes featuring Ru(II), Os(II) and Rh(III) metal centers and naturally occurring bidentate 2-hydroxy-[1,4]-naphthoquinone ligands (lawsone and phthiocol) have been synthesized and characterized in both solid state and solution phase by analytical, spectroscopic, electrochemical and single crystal X-ray diffraction techniques. Comparative studies revealed the influence of the respective metal center (Ru, Os, Rh), leaving group (Cl, Br, I) and arene (p-cymene, toluene, pentamethylcyclopentadienyl), as well as the naphthoquinone ligand on the structural properties and solution speciation. Additionally, cytotoxicity was tested in SW480, CH1/PA-1 and A549 human cancer cell lines showing a broad range of IC50 values.", publisher = "Elsevier", journal = "Journal of Organometallic Chemistry", title = "Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations", volume = "907", doi = "10.1016/j.jorganchem.2019.121070" }
Mészáros, J. P., Geisler, H., Poljarević, J., Roller, A., Legina, M. S., Hejl, M., Jakupec, M. A., Keppler, B. K., Kandioller, W.,& Enyedy, É. A.. (2020). Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations. in Journal of Organometallic Chemistry Elsevier., 907. https://doi.org/10.1016/j.jorganchem.2019.121070
Mészáros JP, Geisler H, Poljarević J, Roller A, Legina MS, Hejl M, Jakupec MA, Keppler BK, Kandioller W, Enyedy ÉA. Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations. in Journal of Organometallic Chemistry. 2020;907. doi:10.1016/j.jorganchem.2019.121070 .
Mészáros, János P., Geisler, Heiko, Poljarević, Jelena, Roller, Alexander, Legina, Maria S., Hejl, Michaela, Jakupec, Michael A., Keppler, Bernhard K., Kandioller, Wolfgang, Enyedy, Éva A., "Naphthoquinones of natural origin: Aqueous chemistry and coordination to half-sandwich organometallic cations" in Journal of Organometallic Chemistry, 907 (2020), https://doi.org/10.1016/j.jorganchem.2019.121070 . .