Optimization of extraction yield and chemical characterization of optimal extract from Juglans nigra L. leaves
Samo za registrovane korisnike
2020
Autori
Rajković, Katarina M.Vasić, Marijana
Drobac, Milica
Mutić, Jelena
Jeremić, Sanja
Simić, Valentina
Stanković, Jovana
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The extraction yield of Juglans nigra L. leaves was assessed at different ethanol concentrations (0–96% (v/v)) and solvent-to-solid ratios (5–20 kg kg−1). The response surface methodology (RSM) and artificial neural network with genetic algorithms (ANN-GA) were developed to optimize the extraction variables. The RSM and ANN-GA models determined 50% (v/v) ethanol concentration and 20 kg kg−1 solvent-to-solid ratio as optimal conditions, ensuring an extraction yield of 27.69 and 27.19 g 100 g−1 of dry leaves. The phenolic compounds in optimal extract were quantified: 3-O-caffeoylquinic acid (2.27 mg g−1of dry leaves), quercetin-3-O-galactoside (10.99 mg g−1 of dry leaves) and quercetin-3-O-rhamnoside (15.07 mg g−1of dry leaves) using high-performance liquid chromatography (HPLC). The minerals in optimal extract were quantified: macro-elements (the relative order by content was: K > Mg > Ca) using inductively coupled plasma optical emission spectrometry (ICP-OES) and micro-elements ...(the relative order by content was: Zn > Rb > Mn > I>Sr > Ni > Cu > Co > V > Ag > Se) using inductively coupled plasma mass spectrometry (ICP-MS). The extraction coefficients for minerals were determined and were highest for K (64.3%) and I (53.5%). Optimization of extraction process resulted in high extraction yield from J. nigra leaves and optimal extract containing different phytochemical compounds.
Ključne reči:
Artificial neural network / Juglans nigra / Minerals / Phenolic constituents / Response surface methodologyIzvor:
Chemical Engineering Research and Design, 2020, 157, 25-33Izdavač:
- Elsevier
Finansiranje / projekti:
- Značaj dokazivanja ranih laboratorijskih biomarkera za ishod invazivnih gljivičnih infekcija kod nas (RS-MESTD-Basic Research (BR or ON)-175034)
- Signalni molekuli u dijabetesu: identifikacija potencijalnih bioloških markera uključenih u modifikaciju i integraciju signalnih puteva u cilju predikcije i intervencije u dijabetesu (RS-MESTD-Basic Research (BR or ON)-173020)
- Ispitivanje lekovitog potencijala biljaka: morfološka, hemijska i farmakološka karakterizacija (RS-MESTD-Basic Research (BR or ON)-173021)
Napomena:
- Peer-reviewed manuscript: http://cherry.chem.bg.ac.rs/handle/123456789/3897
DOI: 10.1016/j.cherd.2020.03.002
ISSN: 0263-8762
WoS: 000528193200003
Scopus: 2-s2.0-85081647717
Kolekcije
Institucija/grupa
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Rajković, Katarina M. AU - Vasić, Marijana AU - Drobac, Milica AU - Mutić, Jelena AU - Jeremić, Sanja AU - Simić, Valentina AU - Stanković, Jovana PY - 2020 UR - https://cherry.chem.bg.ac.rs/handle/123456789/3887 AB - The extraction yield of Juglans nigra L. leaves was assessed at different ethanol concentrations (0–96% (v/v)) and solvent-to-solid ratios (5–20 kg kg−1). The response surface methodology (RSM) and artificial neural network with genetic algorithms (ANN-GA) were developed to optimize the extraction variables. The RSM and ANN-GA models determined 50% (v/v) ethanol concentration and 20 kg kg−1 solvent-to-solid ratio as optimal conditions, ensuring an extraction yield of 27.69 and 27.19 g 100 g−1 of dry leaves. The phenolic compounds in optimal extract were quantified: 3-O-caffeoylquinic acid (2.27 mg g−1of dry leaves), quercetin-3-O-galactoside (10.99 mg g−1 of dry leaves) and quercetin-3-O-rhamnoside (15.07 mg g−1of dry leaves) using high-performance liquid chromatography (HPLC). The minerals in optimal extract were quantified: macro-elements (the relative order by content was: K > Mg > Ca) using inductively coupled plasma optical emission spectrometry (ICP-OES) and micro-elements (the relative order by content was: Zn > Rb > Mn > I>Sr > Ni > Cu > Co > V > Ag > Se) using inductively coupled plasma mass spectrometry (ICP-MS). The extraction coefficients for minerals were determined and were highest for K (64.3%) and I (53.5%). Optimization of extraction process resulted in high extraction yield from J. nigra leaves and optimal extract containing different phytochemical compounds. PB - Elsevier T2 - Chemical Engineering Research and Design T1 - Optimization of extraction yield and chemical characterization of optimal extract from Juglans nigra L. leaves VL - 157 SP - 25 EP - 33 DO - 10.1016/j.cherd.2020.03.002 ER -
@article{ author = "Rajković, Katarina M. and Vasić, Marijana and Drobac, Milica and Mutić, Jelena and Jeremić, Sanja and Simić, Valentina and Stanković, Jovana", year = "2020", abstract = "The extraction yield of Juglans nigra L. leaves was assessed at different ethanol concentrations (0–96% (v/v)) and solvent-to-solid ratios (5–20 kg kg−1). The response surface methodology (RSM) and artificial neural network with genetic algorithms (ANN-GA) were developed to optimize the extraction variables. The RSM and ANN-GA models determined 50% (v/v) ethanol concentration and 20 kg kg−1 solvent-to-solid ratio as optimal conditions, ensuring an extraction yield of 27.69 and 27.19 g 100 g−1 of dry leaves. The phenolic compounds in optimal extract were quantified: 3-O-caffeoylquinic acid (2.27 mg g−1of dry leaves), quercetin-3-O-galactoside (10.99 mg g−1 of dry leaves) and quercetin-3-O-rhamnoside (15.07 mg g−1of dry leaves) using high-performance liquid chromatography (HPLC). The minerals in optimal extract were quantified: macro-elements (the relative order by content was: K > Mg > Ca) using inductively coupled plasma optical emission spectrometry (ICP-OES) and micro-elements (the relative order by content was: Zn > Rb > Mn > I>Sr > Ni > Cu > Co > V > Ag > Se) using inductively coupled plasma mass spectrometry (ICP-MS). The extraction coefficients for minerals were determined and were highest for K (64.3%) and I (53.5%). Optimization of extraction process resulted in high extraction yield from J. nigra leaves and optimal extract containing different phytochemical compounds.", publisher = "Elsevier", journal = "Chemical Engineering Research and Design", title = "Optimization of extraction yield and chemical characterization of optimal extract from Juglans nigra L. leaves", volume = "157", pages = "25-33", doi = "10.1016/j.cherd.2020.03.002" }
Rajković, K. M., Vasić, M., Drobac, M., Mutić, J., Jeremić, S., Simić, V.,& Stanković, J.. (2020). Optimization of extraction yield and chemical characterization of optimal extract from Juglans nigra L. leaves. in Chemical Engineering Research and Design Elsevier., 157, 25-33. https://doi.org/10.1016/j.cherd.2020.03.002
Rajković KM, Vasić M, Drobac M, Mutić J, Jeremić S, Simić V, Stanković J. Optimization of extraction yield and chemical characterization of optimal extract from Juglans nigra L. leaves. in Chemical Engineering Research and Design. 2020;157:25-33. doi:10.1016/j.cherd.2020.03.002 .
Rajković, Katarina M., Vasić, Marijana, Drobac, Milica, Mutić, Jelena, Jeremić, Sanja, Simić, Valentina, Stanković, Jovana, "Optimization of extraction yield and chemical characterization of optimal extract from Juglans nigra L. leaves" in Chemical Engineering Research and Design, 157 (2020):25-33, https://doi.org/10.1016/j.cherd.2020.03.002 . .