Radical Scavenging and Antimicrobial Properties of Polyphenol Rich Waste Wood Extracts
Authors
Smailagić, AnitaRistivojević, Petar
Dimkić, Ivica
Pavlović, Tamara
Dabić Zagorac, Dragana
Veljović, Sonja
Fotirić-Akšić, Milica M.
Meland, Mekjell
Natić, Maja
Article (Published version)
Metadata
Show full item recordAbstract
The main focus of this study is to assess radical scavenging and antimicrobial activities of the 11 wood extracts: oak (Quercus petraea (Matt.) Liebl., Q. robur L., and Q. cerris L.), mulberry (Morus alba L.), myrobalan plum (Prunus cerasifera Ehrh.), black locust (Robinia pseudoacacia L.), and wild cherry (Prunus avium L.). High-performance thin-layer chromatography (HPTLC) provided initial phenolic screening and revealed di erent chemical patterns among investigated wood extracts. To identify individual compounds with radical scavenging activity DPPH-HPTLC, assay was applied. Gallic acid, ferulic and/or ca eic acids were identified as the compounds with the highest contribution of total radical scavenging activity. Principal component analysis was applied on the data set obtained from HPTLC chromatogram to classify samples based on chemical fingerprints: Quercus spp. formed separate clusters from the other wood samples. The wood extracts were evaluated for their antimicrobial activit...y against eight representative human and opportunistic pathogens. The lowest minimum inhibitory concentration (MIC) was recorded against Staphylococcus aureus for black locust, cherry and mulberry wood extracts. This work provided simple, low-cost and high-throughput screening of phenolic compounds and assessments of the radical scavenging properties of selected individual metabolites from natural matrix that contributed to scavenge free radicals.
Keywords:
wood waste / phenolic profile / planar chromatography / DPPH-HPTLC assay / antimicrobial activitySource:
Foods, 2020, 9, 3, 319-Publisher:
- MDPI
Funding / projects:
- Structure-properties relationships of natural and synthetic molecules and their metal complexes (RS-MESTD-Basic Research (BR or ON)-172017)
DOI: 10.3390/foods9030319
ISSN: 2304-8158
WoS: 000526529800113
Scopus: 2-s2.0-85081609393
Collections
Institution/Community
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Smailagić, Anita AU - Ristivojević, Petar AU - Dimkić, Ivica AU - Pavlović, Tamara AU - Dabić Zagorac, Dragana AU - Veljović, Sonja AU - Fotirić-Akšić, Milica M. AU - Meland, Mekjell AU - Natić, Maja PY - 2020 UR - http://cherry.chem.bg.ac.rs/handle/123456789/5293 AB - The main focus of this study is to assess radical scavenging and antimicrobial activities of the 11 wood extracts: oak (Quercus petraea (Matt.) Liebl., Q. robur L., and Q. cerris L.), mulberry (Morus alba L.), myrobalan plum (Prunus cerasifera Ehrh.), black locust (Robinia pseudoacacia L.), and wild cherry (Prunus avium L.). High-performance thin-layer chromatography (HPTLC) provided initial phenolic screening and revealed di erent chemical patterns among investigated wood extracts. To identify individual compounds with radical scavenging activity DPPH-HPTLC, assay was applied. Gallic acid, ferulic and/or ca eic acids were identified as the compounds with the highest contribution of total radical scavenging activity. Principal component analysis was applied on the data set obtained from HPTLC chromatogram to classify samples based on chemical fingerprints: Quercus spp. formed separate clusters from the other wood samples. The wood extracts were evaluated for their antimicrobial activity against eight representative human and opportunistic pathogens. The lowest minimum inhibitory concentration (MIC) was recorded against Staphylococcus aureus for black locust, cherry and mulberry wood extracts. This work provided simple, low-cost and high-throughput screening of phenolic compounds and assessments of the radical scavenging properties of selected individual metabolites from natural matrix that contributed to scavenge free radicals. PB - MDPI T2 - Foods T1 - Radical Scavenging and Antimicrobial Properties of Polyphenol Rich Waste Wood Extracts VL - 9 IS - 3 SP - 319 DO - 10.3390/foods9030319 ER -
@article{ author = "Smailagić, Anita and Ristivojević, Petar and Dimkić, Ivica and Pavlović, Tamara and Dabić Zagorac, Dragana and Veljović, Sonja and Fotirić-Akšić, Milica M. and Meland, Mekjell and Natić, Maja", year = "2020", abstract = "The main focus of this study is to assess radical scavenging and antimicrobial activities of the 11 wood extracts: oak (Quercus petraea (Matt.) Liebl., Q. robur L., and Q. cerris L.), mulberry (Morus alba L.), myrobalan plum (Prunus cerasifera Ehrh.), black locust (Robinia pseudoacacia L.), and wild cherry (Prunus avium L.). High-performance thin-layer chromatography (HPTLC) provided initial phenolic screening and revealed di erent chemical patterns among investigated wood extracts. To identify individual compounds with radical scavenging activity DPPH-HPTLC, assay was applied. Gallic acid, ferulic and/or ca eic acids were identified as the compounds with the highest contribution of total radical scavenging activity. Principal component analysis was applied on the data set obtained from HPTLC chromatogram to classify samples based on chemical fingerprints: Quercus spp. formed separate clusters from the other wood samples. The wood extracts were evaluated for their antimicrobial activity against eight representative human and opportunistic pathogens. The lowest minimum inhibitory concentration (MIC) was recorded against Staphylococcus aureus for black locust, cherry and mulberry wood extracts. This work provided simple, low-cost and high-throughput screening of phenolic compounds and assessments of the radical scavenging properties of selected individual metabolites from natural matrix that contributed to scavenge free radicals.", publisher = "MDPI", journal = "Foods", title = "Radical Scavenging and Antimicrobial Properties of Polyphenol Rich Waste Wood Extracts", volume = "9", number = "3", pages = "319", doi = "10.3390/foods9030319" }
Smailagić, A., Ristivojević, P., Dimkić, I., Pavlović, T., Dabić Zagorac, D., Veljović, S., Fotirić-Akšić, M. M., Meland, M.,& Natić, M.. (2020). Radical Scavenging and Antimicrobial Properties of Polyphenol Rich Waste Wood Extracts. in Foods MDPI., 9(3), 319. https://doi.org/10.3390/foods9030319
Smailagić A, Ristivojević P, Dimkić I, Pavlović T, Dabić Zagorac D, Veljović S, Fotirić-Akšić MM, Meland M, Natić M. Radical Scavenging and Antimicrobial Properties of Polyphenol Rich Waste Wood Extracts. in Foods. 2020;9(3):319. doi:10.3390/foods9030319 .
Smailagić, Anita, Ristivojević, Petar, Dimkić, Ivica, Pavlović, Tamara, Dabić Zagorac, Dragana, Veljović, Sonja, Fotirić-Akšić, Milica M., Meland, Mekjell, Natić, Maja, "Radical Scavenging and Antimicrobial Properties of Polyphenol Rich Waste Wood Extracts" in Foods, 9, no. 3 (2020):319, https://doi.org/10.3390/foods9030319 . .