Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone
Само за регистроване кориснике
2004
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.
Кључне речи:
cytoxazone / asymmetric synthesis / natural products / immunosuppressive compounds / amino alcoholsИзвор:
Tetrahedron Letters, 2004, 45, 5, 955-957Издавач:
- Pergamon-Elsevier Science Ltd, Oxford
DOI: 10.1016/j.tetlet.2003.11.096
ISSN: 0040-4039
WoS: 000188380400015
Scopus: 2-s2.0-0346392218
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Milicevic, S AU - Matović, Radomir AU - Saičić, Radomir PY - 2004 UR - https://cherry.chem.bg.ac.rs/handle/123456789/564 AB - Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved. PB - Pergamon-Elsevier Science Ltd, Oxford T2 - Tetrahedron Letters T1 - Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone VL - 45 IS - 5 SP - 955 EP - 957 DO - 10.1016/j.tetlet.2003.11.096 ER -
@article{ author = "Milicevic, S and Matović, Radomir and Saičić, Radomir", year = "2004", abstract = "Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.", publisher = "Pergamon-Elsevier Science Ltd, Oxford", journal = "Tetrahedron Letters", title = "Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone", volume = "45", number = "5", pages = "955-957", doi = "10.1016/j.tetlet.2003.11.096" }
Milicevic, S., Matović, R.,& Saičić, R.. (2004). Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone. in Tetrahedron Letters Pergamon-Elsevier Science Ltd, Oxford., 45(5), 955-957. https://doi.org/10.1016/j.tetlet.2003.11.096
Milicevic S, Matović R, Saičić R. Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone. in Tetrahedron Letters. 2004;45(5):955-957. doi:10.1016/j.tetlet.2003.11.096 .
Milicevic, S, Matović, Radomir, Saičić, Radomir, "Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone" in Tetrahedron Letters, 45, no. 5 (2004):955-957, https://doi.org/10.1016/j.tetlet.2003.11.096 . .