Polyglycine Modified Glassy Carbon Electrode for Ibuprofen Determination
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2023
Authors
Matijašević, Igor![](/themes/MirageCherry/images/orcid.png)
Kulizić, Mihajlo N.
Bacetić, Ljubica
Gavrilović, Damjan
Baošić, Rada
![](/themes/MirageCherry/images/orcid.png)
Lolić, Aleksandar
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Article (Published version)
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A simple modification of bare glassy carbon electrode by electropolymerization of glycine by cyclic voltammetry was applied to the detection of ibuprofen. The polyglycine modified glassy carbon electrode was characterized by cyclic voltammetry and the electroactive surface area was determined. The study of ibuprofen in acetic acid buffer (0.25 M, pH 4.0) presented an electrocatalytic effect toward ibuprofen oxidation, increasing the current response and decrease of oxidation potential, at the modified electrode compared to the bare. Under the optimal conditions, the modified electrode gave a linear response in the ibuprofen concentration range of 10 to 200 μM, obtained correlation coefficient was 0.9993. the calculated limit of detection (3Sb/m) was 1.0 μM and the limit of quantification (10Sb/m) was 3.5 μM. the sensor was successfully used for the determination of ibuprofen in pharmaceutical preparations with satisfactory recoveries, 93–107 %. The new sensor showed good selectivity, r...epeatability, and reproducibility with satisfactory stability.
Keywords:
cyclic voltammetry / glassy carbon / ibuprofen / pharmaceutical products / polyglycine modificationSource:
ChemistrySelect, 2023, 8, 24, e202300827-Publisher:
- John Wiley and Sons Inc
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200168 (University of Belgrade, Faculty of Chemistry) (RS-MESTD-inst-2020-200168)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200288 (Innovation Center of the Faculty of Chemistry) (RS-MESTD-inst-2020-200288)
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Matijašević, Igor AU - Kulizić, Mihajlo N. AU - Bacetić, Ljubica AU - Gavrilović, Damjan AU - Baošić, Rada AU - Lolić, Aleksandar PY - 2023 UR - http://cherry.chem.bg.ac.rs/handle/123456789/6268 AB - A simple modification of bare glassy carbon electrode by electropolymerization of glycine by cyclic voltammetry was applied to the detection of ibuprofen. The polyglycine modified glassy carbon electrode was characterized by cyclic voltammetry and the electroactive surface area was determined. The study of ibuprofen in acetic acid buffer (0.25 M, pH 4.0) presented an electrocatalytic effect toward ibuprofen oxidation, increasing the current response and decrease of oxidation potential, at the modified electrode compared to the bare. Under the optimal conditions, the modified electrode gave a linear response in the ibuprofen concentration range of 10 to 200 μM, obtained correlation coefficient was 0.9993. the calculated limit of detection (3Sb/m) was 1.0 μM and the limit of quantification (10Sb/m) was 3.5 μM. the sensor was successfully used for the determination of ibuprofen in pharmaceutical preparations with satisfactory recoveries, 93–107 %. The new sensor showed good selectivity, repeatability, and reproducibility with satisfactory stability. PB - John Wiley and Sons Inc T2 - ChemistrySelect T1 - Polyglycine Modified Glassy Carbon Electrode for Ibuprofen Determination VL - 8 IS - 24 SP - e202300827 DO - 10.1002/slct.202300827 ER -
@article{ author = "Matijašević, Igor and Kulizić, Mihajlo N. and Bacetić, Ljubica and Gavrilović, Damjan and Baošić, Rada and Lolić, Aleksandar", year = "2023", abstract = "A simple modification of bare glassy carbon electrode by electropolymerization of glycine by cyclic voltammetry was applied to the detection of ibuprofen. The polyglycine modified glassy carbon electrode was characterized by cyclic voltammetry and the electroactive surface area was determined. The study of ibuprofen in acetic acid buffer (0.25 M, pH 4.0) presented an electrocatalytic effect toward ibuprofen oxidation, increasing the current response and decrease of oxidation potential, at the modified electrode compared to the bare. Under the optimal conditions, the modified electrode gave a linear response in the ibuprofen concentration range of 10 to 200 μM, obtained correlation coefficient was 0.9993. the calculated limit of detection (3Sb/m) was 1.0 μM and the limit of quantification (10Sb/m) was 3.5 μM. the sensor was successfully used for the determination of ibuprofen in pharmaceutical preparations with satisfactory recoveries, 93–107 %. The new sensor showed good selectivity, repeatability, and reproducibility with satisfactory stability.", publisher = "John Wiley and Sons Inc", journal = "ChemistrySelect", title = "Polyglycine Modified Glassy Carbon Electrode for Ibuprofen Determination", volume = "8", number = "24", pages = "e202300827", doi = "10.1002/slct.202300827" }
Matijašević, I., Kulizić, M. N., Bacetić, L., Gavrilović, D., Baošić, R.,& Lolić, A.. (2023). Polyglycine Modified Glassy Carbon Electrode for Ibuprofen Determination. in ChemistrySelect John Wiley and Sons Inc., 8(24), e202300827. https://doi.org/10.1002/slct.202300827
Matijašević I, Kulizić MN, Bacetić L, Gavrilović D, Baošić R, Lolić A. Polyglycine Modified Glassy Carbon Electrode for Ibuprofen Determination. in ChemistrySelect. 2023;8(24):e202300827. doi:10.1002/slct.202300827 .
Matijašević, Igor, Kulizić, Mihajlo N., Bacetić, Ljubica, Gavrilović, Damjan, Baošić, Rada, Lolić, Aleksandar, "Polyglycine Modified Glassy Carbon Electrode for Ibuprofen Determination" in ChemistrySelect, 8, no. 24 (2023):e202300827, https://doi.org/10.1002/slct.202300827 . .