A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid using Carbon Paste/Copper Schiff Base Composite Electrode
Authorized Users Only
2023
Authors
Kulizić, Mihajlo N.Stanković, Milan
Rašić, Marija
Mijatović, Aleksandar
Baošić, Rada
Lolić, Aleksandar
Article (Published version)
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In this paper, a simple, sensitive, and precise flow injection system was optimized and applied to ascorbic acid determination with a carbon paste electrode modified with the Schiff base copper complex. The modified sensor showed increased sensitivity toward ascorbic acid oxidation with a decrease of oxidation potential by 200 mV. Under optimized flow parameters, working potential, gasket thickness, sample and reaction coil volumes, and flow rate, the developed flow system gave a linear response from 5 to 75 μmol/L of ascorbic acid. The calculated limit of detection was 4.5 μmol/L, calculated as 3σ/s which corresponds to the absolute value of 40 ng for the 50 μL sample coil. The precision for six consecutive injections of 5 and 75 μmol/L ascorbic acid solutions was determined as a relative standard deviation of 5.8 % and 1.5 %, respectively. The flow injection system enabled up to 120 analyses per hour. An optimized flow system was applied to the determination of ascorbic acid in dieta...ry supplements, after simple preparation.
Keywords:
amperometry / ascorbic acid / dietary supplements / flow injection analysis / modified carbon paste electrodeSource:
2023, 8, 48, e202304631-Publisher:
- Wiley
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200126 (University of Belgrade, Faculty of Mining and Geology) (RS-MESTD-inst-2020-200126)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200168 (University of Belgrade, Faculty of Chemistry) (RS-MESTD-inst-2020-200168)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200288 (Innovation Center of the Faculty of Chemistry) (RS-MESTD-inst-2020-200288)
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Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Kulizić, Mihajlo N. AU - Stanković, Milan AU - Rašić, Marija AU - Mijatović, Aleksandar AU - Baošić, Rada AU - Lolić, Aleksandar PY - 2023 UR - http://cherry.chem.bg.ac.rs/handle/123456789/6431 AB - In this paper, a simple, sensitive, and precise flow injection system was optimized and applied to ascorbic acid determination with a carbon paste electrode modified with the Schiff base copper complex. The modified sensor showed increased sensitivity toward ascorbic acid oxidation with a decrease of oxidation potential by 200 mV. Under optimized flow parameters, working potential, gasket thickness, sample and reaction coil volumes, and flow rate, the developed flow system gave a linear response from 5 to 75 μmol/L of ascorbic acid. The calculated limit of detection was 4.5 μmol/L, calculated as 3σ/s which corresponds to the absolute value of 40 ng for the 50 μL sample coil. The precision for six consecutive injections of 5 and 75 μmol/L ascorbic acid solutions was determined as a relative standard deviation of 5.8 % and 1.5 %, respectively. The flow injection system enabled up to 120 analyses per hour. An optimized flow system was applied to the determination of ascorbic acid in dietary supplements, after simple preparation. PB - Wiley T1 - A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid using Carbon Paste/Copper Schiff Base Composite Electrode VL - 8 IS - 48 SP - e202304631 DO - 10.1002/slct.202304631 ER -
@article{ author = "Kulizić, Mihajlo N. and Stanković, Milan and Rašić, Marija and Mijatović, Aleksandar and Baošić, Rada and Lolić, Aleksandar", year = "2023", abstract = "In this paper, a simple, sensitive, and precise flow injection system was optimized and applied to ascorbic acid determination with a carbon paste electrode modified with the Schiff base copper complex. The modified sensor showed increased sensitivity toward ascorbic acid oxidation with a decrease of oxidation potential by 200 mV. Under optimized flow parameters, working potential, gasket thickness, sample and reaction coil volumes, and flow rate, the developed flow system gave a linear response from 5 to 75 μmol/L of ascorbic acid. The calculated limit of detection was 4.5 μmol/L, calculated as 3σ/s which corresponds to the absolute value of 40 ng for the 50 μL sample coil. The precision for six consecutive injections of 5 and 75 μmol/L ascorbic acid solutions was determined as a relative standard deviation of 5.8 % and 1.5 %, respectively. The flow injection system enabled up to 120 analyses per hour. An optimized flow system was applied to the determination of ascorbic acid in dietary supplements, after simple preparation.", publisher = "Wiley", title = "A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid using Carbon Paste/Copper Schiff Base Composite Electrode", volume = "8", number = "48", pages = "e202304631", doi = "10.1002/slct.202304631" }
Kulizić, M. N., Stanković, M., Rašić, M., Mijatović, A., Baošić, R.,& Lolić, A.. (2023). A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid using Carbon Paste/Copper Schiff Base Composite Electrode. Wiley., 8(48), e202304631. https://doi.org/10.1002/slct.202304631
Kulizić MN, Stanković M, Rašić M, Mijatović A, Baošić R, Lolić A. A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid using Carbon Paste/Copper Schiff Base Composite Electrode. 2023;8(48):e202304631. doi:10.1002/slct.202304631 .
Kulizić, Mihajlo N., Stanković, Milan, Rašić, Marija, Mijatović, Aleksandar, Baošić, Rada, Lolić, Aleksandar, "A Simple Flow Injection System for Amperometric Detection of Ascorbic Acid using Carbon Paste/Copper Schiff Base Composite Electrode", 8, no. 48 (2023):e202304631, https://doi.org/10.1002/slct.202304631 . .