Structure-retention relationship study of diastereomeric (Z)- and (E)-2-alkylidene-4-oxothiazolidines
Само за регистроване кориснике
2007
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Quantitative structure-retention relationship (QSRR) was developed for a series of the (Z)- and (E)-2-allcylidene-4-oxothiazolidine derivatives by the multiple linear regression (MLR) analysis. Full geometry optimization based on Austin Model 1 (AM1) semiempirical molecular orbital method was carried out and a set of physicochemical molecular descriptors was calculated from the optimized structures. In order to obtain useful experimental parameters, the lipophilic character of analytes was measured by RP-TLC, and lipophilicity parameters were correlated with physicochemical structural descriptors. Statistically significant and physically meaningful structure-retention relationships were obtained.
Кључне речи:
diastereomers / lipophilicity / multiple linear regression / quantitative structure retention relationship / RP-TLCИзвор:
Journal of Separation Science, 2007, 30, 14, 2241-2248Издавач:
- Wiley-V C H Verlag Gmbh, Weinheim
DOI: 10.1002/jssc.200700152
ISSN: 1615-9306
PubMed: 17685377
WoS: 000249800300010
Scopus: 2-s2.0-34848918147
Колекције
Институција/група
Hemijski fakultet / Faculty of ChemistryTY - JOUR AU - Natić, Maja AU - Marković, Rade AU - Milojković-Opsenica, Dušanka AU - Tešić, Živoslav Lj. PY - 2007 UR - https://cherry.chem.bg.ac.rs/handle/123456789/879 AB - Quantitative structure-retention relationship (QSRR) was developed for a series of the (Z)- and (E)-2-allcylidene-4-oxothiazolidine derivatives by the multiple linear regression (MLR) analysis. Full geometry optimization based on Austin Model 1 (AM1) semiempirical molecular orbital method was carried out and a set of physicochemical molecular descriptors was calculated from the optimized structures. In order to obtain useful experimental parameters, the lipophilic character of analytes was measured by RP-TLC, and lipophilicity parameters were correlated with physicochemical structural descriptors. Statistically significant and physically meaningful structure-retention relationships were obtained. PB - Wiley-V C H Verlag Gmbh, Weinheim T2 - Journal of Separation Science T1 - Structure-retention relationship study of diastereomeric (Z)- and (E)-2-alkylidene-4-oxothiazolidines VL - 30 IS - 14 SP - 2241 EP - 2248 DO - 10.1002/jssc.200700152 ER -
@article{ author = "Natić, Maja and Marković, Rade and Milojković-Opsenica, Dušanka and Tešić, Živoslav Lj.", year = "2007", abstract = "Quantitative structure-retention relationship (QSRR) was developed for a series of the (Z)- and (E)-2-allcylidene-4-oxothiazolidine derivatives by the multiple linear regression (MLR) analysis. Full geometry optimization based on Austin Model 1 (AM1) semiempirical molecular orbital method was carried out and a set of physicochemical molecular descriptors was calculated from the optimized structures. In order to obtain useful experimental parameters, the lipophilic character of analytes was measured by RP-TLC, and lipophilicity parameters were correlated with physicochemical structural descriptors. Statistically significant and physically meaningful structure-retention relationships were obtained.", publisher = "Wiley-V C H Verlag Gmbh, Weinheim", journal = "Journal of Separation Science", title = "Structure-retention relationship study of diastereomeric (Z)- and (E)-2-alkylidene-4-oxothiazolidines", volume = "30", number = "14", pages = "2241-2248", doi = "10.1002/jssc.200700152" }
Natić, M., Marković, R., Milojković-Opsenica, D.,& Tešić, Ž. Lj.. (2007). Structure-retention relationship study of diastereomeric (Z)- and (E)-2-alkylidene-4-oxothiazolidines. in Journal of Separation Science Wiley-V C H Verlag Gmbh, Weinheim., 30(14), 2241-2248. https://doi.org/10.1002/jssc.200700152
Natić M, Marković R, Milojković-Opsenica D, Tešić ŽL. Structure-retention relationship study of diastereomeric (Z)- and (E)-2-alkylidene-4-oxothiazolidines. in Journal of Separation Science. 2007;30(14):2241-2248. doi:10.1002/jssc.200700152 .
Natić, Maja, Marković, Rade, Milojković-Opsenica, Dušanka, Tešić, Živoslav Lj., "Structure-retention relationship study of diastereomeric (Z)- and (E)-2-alkylidene-4-oxothiazolidines" in Journal of Separation Science, 30, no. 14 (2007):2241-2248, https://doi.org/10.1002/jssc.200700152 . .