@conference{
author = "Cvijetić, Ilija and Ivković, Đurđa and Todorović, Petar and Andrić, Filip and Ristivojević, Petar",
year = "2023",
abstract = "DES are mixtures of a hydrogen bond donor (HBD) and a hydrogen bond acceptor (HBA) that, when combined in a specific molar ratio, exhibit a significant decrease in melting point and become liquid at room temperature. DES can be tailored to meet different physicochemical requirements by altering the HBA:HBD ratio or the nature of the compounds. In this study, we utilized the COSMO-RS method to predict the activity coefficients of 12 phenolic compounds in 105 NaDES. These NaDES contained equimolar mixtures of betaine, carnitine, creatine, and ornithine as HBAs and various sugars and amino acids as HBDs. The NaDES were compared to methanol, and several mixtures exhibited higher affinities to all phenolics. The most promising NaDES were betaine-glycerol, betaine-xylitol, and carnitine-urea. We are currently conducting experimental validation of the extraction efficiency of these cosmetically acceptable solvents. In summary, we have identified promising NaDES mixtures that could replace conventional solvents and contribute to the development of sustainable, bio-based extracts.
Acknowledgment: This research was funded by The Science Fund of the Republic of Serbia, Serbian Science and Diaspora Collaboration Program, No. 389927, and the MNTR, contracts No. 451-03-47/2023-01/200168 and 451-03-47/2023-01/200288.",
journal = "59th Meeting of the Serbian Chemical Society, Book of Abstracts, June 1-2, 2023, Novi Sad, Serbia",
title = "Screening natural deep eutectic solvents (NaDES) using COSMO-RS for sustainable and environmentally-friendly cosmetic ingredients",
number = "66",
url = "https://hdl.handle.net/21.15107/rcub_cherry_6222"
}