Weiler, Hope

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882c5748-1982-4c15-a251-8dc204acbef6
  • Weiler, Hope (2)
  • Weiler, Hope A. (1)
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Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy

Đekić-Ivanković, Marija; Weiler, Hope; Jones, Glenville; Kaufmann, Martin; Kaluđerović, Jovana; Aleksić-Veličković, Vesna; Mandić, Ljuba M.; Glibetic, Maria

(Cambridge Univ Press, Cambridge, 2017)

TY  - JOUR
AU  - Đekić-Ivanković, Marija
AU  - Weiler, Hope
AU  - Jones, Glenville
AU  - Kaufmann, Martin
AU  - Kaluđerović, Jovana
AU  - Aleksić-Veličković, Vesna
AU  - Mandić, Ljuba M.
AU  - Glibetic, Maria
PY  - 2017
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2161
AB  - Objective: The objective of the present study was to determine if vitamin D intake and status are associated with pre-eclampsia in a country without a vitamin D fortification policy. Design: A case-control study of pregnancies with (case) and without (control) pre-eclampsia was conducted from January to April when UVB is minimal. Maternal and cord blood obtained at delivery were measured for plasma 25-hydroxycholecalciferol (25-OH-D-3), 3-epimer of 25-OH-D-3 (3-epi-25-OH-D-3) and 24,25-dihydroxycholecalciferol (24,25-(OH)(2)D-3) by LC-MS/MS and maternal 1,25-dihydroxyvitamin D (1,25-(OH) 2D). Differences between groups were tested with ANOVA and Bonferroni post hoc tests (P  lt  0.05). Setting: Clinical Center of Serbia. Subjects: Pregnant women with and without pre-eclampsia (n 60) and their infants. Results: Exogenous vitamin D intake (0.95-16.25 mu g/d (38-650 IU/d)) was not significantly different between groups. Women with pre-eclampsia delivered infants at an earlier gestational age and had significantly lower mean total plasma 25-hydroxyvitamin D (25-OH-D; case: 11.2 (SD 5.1); control: 16.1 (SD 5.7) ng/ml; P=0.0006), 25-OH-D-3 (case: 10.0 (SD 4.9); control: 14.2 (SD 5.8) ng/ml; P=0.002), 3-epi-25-OH-D-3 (case: 0.5 (SD 0.2); control: 0.7 (SD 0.2) ng/ml; P=0.0007) and 1,25-(OH)(2)D (case: 56.5 (SD 26.6); control: 81.0 (SD 25.7) pg/ml; P=0.018), while 24,25-(OH)(2)D-3 was not different between groups. Infants did not differ in total plasma 25-OH-D, 25-OH-D-3, 3-epi-25-OH-D-3 and 24,25-(OH)(2)D-3, but the mean proportion of 3-epi-25-OH-D-3 was higher in the infant case group (case: 7.9 (SD 1.1); control: 7.0 (SD 1.4) % of total 25-OH-D-3; P=0.005). Conclusions: A high prevalence of vitamin D deficiency, as defined by plasma 25-OH-D lt 12 ng/ml, was observed in 47 % of all mothers and 77 % of all infants. These data underscore the need for prenatal vitamin D supplementation and a food fortification policy in Serbia.
PB  - Cambridge Univ Press, Cambridge
T2  - Public Health Nutrition
T1  - Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy
VL  - 20
IS  - 10
SP  - 1825
EP  - 1835
DO  - 10.1017/S1368980016000409
ER  - 
@article{
author = "Đekić-Ivanković, Marija and Weiler, Hope and Jones, Glenville and Kaufmann, Martin and Kaluđerović, Jovana and Aleksić-Veličković, Vesna and Mandić, Ljuba M. and Glibetic, Maria",
year = "2017",
abstract = "Objective: The objective of the present study was to determine if vitamin D intake and status are associated with pre-eclampsia in a country without a vitamin D fortification policy. Design: A case-control study of pregnancies with (case) and without (control) pre-eclampsia was conducted from January to April when UVB is minimal. Maternal and cord blood obtained at delivery were measured for plasma 25-hydroxycholecalciferol (25-OH-D-3), 3-epimer of 25-OH-D-3 (3-epi-25-OH-D-3) and 24,25-dihydroxycholecalciferol (24,25-(OH)(2)D-3) by LC-MS/MS and maternal 1,25-dihydroxyvitamin D (1,25-(OH) 2D). Differences between groups were tested with ANOVA and Bonferroni post hoc tests (P  lt  0.05). Setting: Clinical Center of Serbia. Subjects: Pregnant women with and without pre-eclampsia (n 60) and their infants. Results: Exogenous vitamin D intake (0.95-16.25 mu g/d (38-650 IU/d)) was not significantly different between groups. Women with pre-eclampsia delivered infants at an earlier gestational age and had significantly lower mean total plasma 25-hydroxyvitamin D (25-OH-D; case: 11.2 (SD 5.1); control: 16.1 (SD 5.7) ng/ml; P=0.0006), 25-OH-D-3 (case: 10.0 (SD 4.9); control: 14.2 (SD 5.8) ng/ml; P=0.002), 3-epi-25-OH-D-3 (case: 0.5 (SD 0.2); control: 0.7 (SD 0.2) ng/ml; P=0.0007) and 1,25-(OH)(2)D (case: 56.5 (SD 26.6); control: 81.0 (SD 25.7) pg/ml; P=0.018), while 24,25-(OH)(2)D-3 was not different between groups. Infants did not differ in total plasma 25-OH-D, 25-OH-D-3, 3-epi-25-OH-D-3 and 24,25-(OH)(2)D-3, but the mean proportion of 3-epi-25-OH-D-3 was higher in the infant case group (case: 7.9 (SD 1.1); control: 7.0 (SD 1.4) % of total 25-OH-D-3; P=0.005). Conclusions: A high prevalence of vitamin D deficiency, as defined by plasma 25-OH-D lt 12 ng/ml, was observed in 47 % of all mothers and 77 % of all infants. These data underscore the need for prenatal vitamin D supplementation and a food fortification policy in Serbia.",
publisher = "Cambridge Univ Press, Cambridge",
journal = "Public Health Nutrition",
title = "Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy",
volume = "20",
number = "10",
pages = "1825-1835",
doi = "10.1017/S1368980016000409"
}
Đekić-Ivanković, M., Weiler, H., Jones, G., Kaufmann, M., Kaluđerović, J., Aleksić-Veličković, V., Mandić, L. M.,& Glibetic, M.. (2017). Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy. in Public Health Nutrition
Cambridge Univ Press, Cambridge., 20(10), 1825-1835.
https://doi.org/10.1017/S1368980016000409
Đekić-Ivanković M, Weiler H, Jones G, Kaufmann M, Kaluđerović J, Aleksić-Veličković V, Mandić LM, Glibetic M. Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy. in Public Health Nutrition. 2017;20(10):1825-1835.
doi:10.1017/S1368980016000409 .
Đekić-Ivanković, Marija, Weiler, Hope, Jones, Glenville, Kaufmann, Martin, Kaluđerović, Jovana, Aleksić-Veličković, Vesna, Mandić, Ljuba M., Glibetic, Maria, "Vitamin D status in mothers with pre-eclampsia and their infants: a case-control study from Serbia, a country without a vitamin D fortification policy" in Public Health Nutrition, 20, no. 10 (2017):1825-1835,
https://doi.org/10.1017/S1368980016000409 . .
18
6
13
12

Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model

Đekić-Ivanković, Marija; Weiler, Hope A.; Nikolic, Marina; Kadvan, Agnes; Gurinovic, Mirjana; Mandić, Ljuba M.; Glibetic, Maria

(Cambridge Univ Press, Cambridge, 2016)

TY  - JOUR
AU  - Đekić-Ivanković, Marija
AU  - Weiler, Hope A.
AU  - Nikolic, Marina
AU  - Kadvan, Agnes
AU  - Gurinovic, Mirjana
AU  - Mandić, Ljuba M.
AU  - Glibetic, Maria
PY  - 2016
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1905
AB  - Objective: The objective of the present study was to examine the external validity of an FFQ designed to estimate dietary vitamin D intake compared with a plasma biomarker and three repeated 24 h dietary recalls in women of reproductive age in Serbia, where there is no exposure to food fortified with vitamin D. The method of triads was applied. Design: In a cross-sectional study, 422 women completed the Women and Reproductive Health FFQ (WRH-FFQ) during the winter months. From a representative subgroup (n 44), three 24 h dietary recalls and anthropometric parameters were collected as well as a fasting blood sample for vitamin D biomarker analyses. Correlation coefficients were calculated between each of the dietary methods. Validity coefficients, as a correlation between the measured and estimated 'true' exposure, were calculated using the method of triads. Bland-Altman plots were also constructed. Setting: Three major universities in Serbia. Subjects: Healthy young women (n 422) aged 18-35 years. Results: The WRH-FFQ estimate of vitamin D intake for all participants was 4.0 (SD 3.3) mu g/d and 3.1 (SD 2.3) mu g/d for the subgroup. Bland-Altman plots for these intakes showed high agreement. Validity coefficients for the FFQ, 24 h recall and biomarker were. rho(QI) = 0.847 (95 % CI 0.564, 0.928), rho(RI) = 0.810 (95 % CI 0.537, 0.997) and rho(BI) = 0.499 (95 % CI 0.190, 0.840), while the correlation coefficients were 0.686, 0.422 and 0.404. Conclusions: The FFQ applied in the present study is a valid tool for assessing dietary vitamin D intake in women living in Serbia, a region without mandatory vitamin D food fortification.
PB  - Cambridge Univ Press, Cambridge
T2  - Public Health Nutrition
T1  - Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model
VL  - 19
IS  - 4
SP  - 437
EP  - 445
DO  - 10.1017/S136898001500138X
ER  - 
@article{
author = "Đekić-Ivanković, Marija and Weiler, Hope A. and Nikolic, Marina and Kadvan, Agnes and Gurinovic, Mirjana and Mandić, Ljuba M. and Glibetic, Maria",
year = "2016",
abstract = "Objective: The objective of the present study was to examine the external validity of an FFQ designed to estimate dietary vitamin D intake compared with a plasma biomarker and three repeated 24 h dietary recalls in women of reproductive age in Serbia, where there is no exposure to food fortified with vitamin D. The method of triads was applied. Design: In a cross-sectional study, 422 women completed the Women and Reproductive Health FFQ (WRH-FFQ) during the winter months. From a representative subgroup (n 44), three 24 h dietary recalls and anthropometric parameters were collected as well as a fasting blood sample for vitamin D biomarker analyses. Correlation coefficients were calculated between each of the dietary methods. Validity coefficients, as a correlation between the measured and estimated 'true' exposure, were calculated using the method of triads. Bland-Altman plots were also constructed. Setting: Three major universities in Serbia. Subjects: Healthy young women (n 422) aged 18-35 years. Results: The WRH-FFQ estimate of vitamin D intake for all participants was 4.0 (SD 3.3) mu g/d and 3.1 (SD 2.3) mu g/d for the subgroup. Bland-Altman plots for these intakes showed high agreement. Validity coefficients for the FFQ, 24 h recall and biomarker were. rho(QI) = 0.847 (95 % CI 0.564, 0.928), rho(RI) = 0.810 (95 % CI 0.537, 0.997) and rho(BI) = 0.499 (95 % CI 0.190, 0.840), while the correlation coefficients were 0.686, 0.422 and 0.404. Conclusions: The FFQ applied in the present study is a valid tool for assessing dietary vitamin D intake in women living in Serbia, a region without mandatory vitamin D food fortification.",
publisher = "Cambridge Univ Press, Cambridge",
journal = "Public Health Nutrition",
title = "Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model",
volume = "19",
number = "4",
pages = "437-445",
doi = "10.1017/S136898001500138X"
}
Đekić-Ivanković, M., Weiler, H. A., Nikolic, M., Kadvan, A., Gurinovic, M., Mandić, L. M.,& Glibetic, M.. (2016). Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model. in Public Health Nutrition
Cambridge Univ Press, Cambridge., 19(4), 437-445.
https://doi.org/10.1017/S136898001500138X
Đekić-Ivanković M, Weiler HA, Nikolic M, Kadvan A, Gurinovic M, Mandić LM, Glibetic M. Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model. in Public Health Nutrition. 2016;19(4):437-445.
doi:10.1017/S136898001500138X .
Đekić-Ivanković, Marija, Weiler, Hope A., Nikolic, Marina, Kadvan, Agnes, Gurinovic, Mirjana, Mandić, Ljuba M., Glibetic, Maria, "Validity of an FFQ assessing the vitamin D intake of young Serbian women living in a region without food fortification: the method of triads model" in Public Health Nutrition, 19, no. 4 (2016):437-445,
https://doi.org/10.1017/S136898001500138X . .
25
14
20
20

Vitamin D Status is Low in Mothers with Preeclampsia and Their Infants: a Case Control Study from Serbia

Đekić-Ivanković, Marija; Weiler, Hope; Jones, Glenville; Kaufmann, Martin; Kaluđerović, Jovana; Aleksić-Veličković, Vesna; Mandić, Ljuba M.; Glibetic, Maria

(Federation Amer Soc Exp Biol, Bethesda, 2015)

TY  - CONF
AU  - Đekić-Ivanković, Marija
AU  - Weiler, Hope
AU  - Jones, Glenville
AU  - Kaufmann, Martin
AU  - Kaluđerović, Jovana
AU  - Aleksić-Veličković, Vesna
AU  - Mandić, Ljuba M.
AU  - Glibetic, Maria
PY  - 2015
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/1969
PB  - Federation Amer Soc Exp Biol, Bethesda
C3  - FASEB Journal / Federation of American Societies for Experimental Biology
T1  - Vitamin D Status is Low in Mothers with Preeclampsia and Their Infants: a Case Control Study from Serbia
VL  - 29
UR  - https://hdl.handle.net/21.15107/rcub_cherry_1969
ER  - 
@conference{
author = "Đekić-Ivanković, Marija and Weiler, Hope and Jones, Glenville and Kaufmann, Martin and Kaluđerović, Jovana and Aleksić-Veličković, Vesna and Mandić, Ljuba M. and Glibetic, Maria",
year = "2015",
publisher = "Federation Amer Soc Exp Biol, Bethesda",
journal = "FASEB Journal / Federation of American Societies for Experimental Biology",
title = "Vitamin D Status is Low in Mothers with Preeclampsia and Their Infants: a Case Control Study from Serbia",
volume = "29",
url = "https://hdl.handle.net/21.15107/rcub_cherry_1969"
}
Đekić-Ivanković, M., Weiler, H., Jones, G., Kaufmann, M., Kaluđerović, J., Aleksić-Veličković, V., Mandić, L. M.,& Glibetic, M.. (2015). Vitamin D Status is Low in Mothers with Preeclampsia and Their Infants: a Case Control Study from Serbia. in FASEB Journal / Federation of American Societies for Experimental Biology
Federation Amer Soc Exp Biol, Bethesda., 29.
https://hdl.handle.net/21.15107/rcub_cherry_1969
Đekić-Ivanković M, Weiler H, Jones G, Kaufmann M, Kaluđerović J, Aleksić-Veličković V, Mandić LM, Glibetic M. Vitamin D Status is Low in Mothers with Preeclampsia and Their Infants: a Case Control Study from Serbia. in FASEB Journal / Federation of American Societies for Experimental Biology. 2015;29.
https://hdl.handle.net/21.15107/rcub_cherry_1969 .
Đekić-Ivanković, Marija, Weiler, Hope, Jones, Glenville, Kaufmann, Martin, Kaluđerović, Jovana, Aleksić-Veličković, Vesna, Mandić, Ljuba M., Glibetic, Maria, "Vitamin D Status is Low in Mothers with Preeclampsia and Their Infants: a Case Control Study from Serbia" in FASEB Journal / Federation of American Societies for Experimental Biology, 29 (2015),
https://hdl.handle.net/21.15107/rcub_cherry_1969 .