Milić Komić, Sonja

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  • Milić Komić, Sonja (5)

Author's Bibliography

Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties

Milić Komić, Sonja; Živanović, Bojana; Dumanović, Jelena; Kolarž, Predrag; Sedlarević Zorić, Ana; Morina, Filis; Vidović, Marija; Veljović Jovanović, Sonja

(MDPI, 2023)

TY  - JOUR
AU  - Milić Komić, Sonja
AU  - Živanović, Bojana
AU  - Dumanović, Jelena
AU  - Kolarž, Predrag
AU  - Sedlarević Zorić, Ana
AU  - Morina, Filis
AU  - Vidović, Marija
AU  - Veljović Jovanović, Sonja
PY  - 2023
UR  - http://cherry.chem.bg.ac.rs/handle/123456789/6386
AB  - Three basil plant varieties (Ocimum basilicum var. Genovese, Ocimum × citriodorum, and Ocimum basilicum var. purpurascens) were grown under moderate light (about 300 µmol photons m−2 s−1) in a glasshouse or growth chamber and then either transferred to an open field (average daily dose: 29.2 kJ m−2 d−1) or additionally exposed to UV-B irradiation in a growth chamber (29.16 kJ m−2 d−1), to reveal the variety-specific and light-specific acclimation responses. Total antioxidant capacity (TAC), phenolic profile, ascorbate content, and class III peroxidase (POD) activity were used to determine the antioxidant status of leaves under all four light regimes. Exposure to high solar irradiation at the open field resulted in an increase in TAC, total hydroxycinnamic acids (HCAs, especially caffeic acid), flavonoids, and epidermal UV-absorbing substances in all three varieties, as well as a two-fold increase in the leaf dry/fresh weight ratio. The supplemental UV-B irradiation induced preferential accumulation of HCAs (rosmarinic acid) over flavonoids, increased TAC and POD activity, but decreased the ascorbate content in the leaves, and inhibited the accumulation of epidermal flavonoids in all basil varieties. Furthermore, characteristic leaf curling and UV-B-induced inhibition of plant growth were observed in all basil varieties, while a pro-oxidant effect of UV-B was indicated with H2O2 accumulation in the leaves and spotty leaf browning. The extent of these morphological changes, and oxidative damage depended on the basil cultivar, implies a genotype-specific tolerance mechanism to high doses of UV-B irradiation.
PB  - MDPI
T2  - International Journal of Molecular Sciences
T1  - Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties
VL  - 24
IS  - 20
SP  - 15350
DO  - 10.3390/ijms242015350
ER  - 
@article{
author = "Milić Komić, Sonja and Živanović, Bojana and Dumanović, Jelena and Kolarž, Predrag and Sedlarević Zorić, Ana and Morina, Filis and Vidović, Marija and Veljović Jovanović, Sonja",
year = "2023",
abstract = "Three basil plant varieties (Ocimum basilicum var. Genovese, Ocimum × citriodorum, and Ocimum basilicum var. purpurascens) were grown under moderate light (about 300 µmol photons m−2 s−1) in a glasshouse or growth chamber and then either transferred to an open field (average daily dose: 29.2 kJ m−2 d−1) or additionally exposed to UV-B irradiation in a growth chamber (29.16 kJ m−2 d−1), to reveal the variety-specific and light-specific acclimation responses. Total antioxidant capacity (TAC), phenolic profile, ascorbate content, and class III peroxidase (POD) activity were used to determine the antioxidant status of leaves under all four light regimes. Exposure to high solar irradiation at the open field resulted in an increase in TAC, total hydroxycinnamic acids (HCAs, especially caffeic acid), flavonoids, and epidermal UV-absorbing substances in all three varieties, as well as a two-fold increase in the leaf dry/fresh weight ratio. The supplemental UV-B irradiation induced preferential accumulation of HCAs (rosmarinic acid) over flavonoids, increased TAC and POD activity, but decreased the ascorbate content in the leaves, and inhibited the accumulation of epidermal flavonoids in all basil varieties. Furthermore, characteristic leaf curling and UV-B-induced inhibition of plant growth were observed in all basil varieties, while a pro-oxidant effect of UV-B was indicated with H2O2 accumulation in the leaves and spotty leaf browning. The extent of these morphological changes, and oxidative damage depended on the basil cultivar, implies a genotype-specific tolerance mechanism to high doses of UV-B irradiation.",
publisher = "MDPI",
journal = "International Journal of Molecular Sciences",
title = "Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties",
volume = "24",
number = "20",
pages = "15350",
doi = "10.3390/ijms242015350"
}
Milić Komić, S., Živanović, B., Dumanović, J., Kolarž, P., Sedlarević Zorić, A., Morina, F., Vidović, M.,& Veljović Jovanović, S.. (2023). Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties. in International Journal of Molecular Sciences
MDPI., 24(20), 15350.
https://doi.org/10.3390/ijms242015350
Milić Komić S, Živanović B, Dumanović J, Kolarž P, Sedlarević Zorić A, Morina F, Vidović M, Veljović Jovanović S. Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties. in International Journal of Molecular Sciences. 2023;24(20):15350.
doi:10.3390/ijms242015350 .
Milić Komić, Sonja, Živanović, Bojana, Dumanović, Jelena, Kolarž, Predrag, Sedlarević Zorić, Ana, Morina, Filis, Vidović, Marija, Veljović Jovanović, Sonja, "Differential Antioxidant Response to Supplemental UV-B Irradiation and Sunlight in Three Basil Varieties" in International Journal of Molecular Sciences, 24, no. 20 (2023):15350,
https://doi.org/10.3390/ijms242015350 . .
4
1

Hydroxyl radical scavenging potential of the late embryogenesis abundant proteins (LEA) proteins from Ramonda serbica – in silico approach

Milić Komić, Sonja; Stevanović, Strahinja; Vidović, Marija

(2021)

TY  - CONF
AU  - Milić Komić, Sonja
AU  - Stevanović, Strahinja
AU  - Vidović, Marija
PY  - 2021
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4507
AB  - Ramonda serbica Panc. is a resurrection plant that can survive long desiccation periods (extreme loss of cellular water). The accumulation of late embryogenesis abundant proteins (LEAPs) is a crucial step in desiccation tolerance mechanism. Based on in vitro studies, LEAPs can be involved in antioxidative defense, ion sequestration, structural stabilization of both membranes and enzymes during freezing or drying, while by forming intracellular proteinaceous condensates they increase structural integrity and intracellular viscosity of cells during desiccation. Here we investigated the antioxidative potential of LEAPs identified by de novo transcriptomics of R. serbica, based on their primary and secondary confirmation. In our
previous work [1], we displayed the antioxidative capacity of 20 free proteogenic amino acids
(FAA) through determining their hydroxyl radical (•OH, generated in Fenton reaction) scavenging
rate by using electron paramagnetic resonance. These results served as a basis for generating a model for prediction of •OH scavenging activity for selected proteins. In addition, the model was built based on protein primary sequences, hydrophobicity, 3D structure and predicted solvent accessible area. Manually curated data for peptides and proteins with experimentally determined •OH scavenging rate were used for training and testing. The model was fed into machine learning algorithm and •OH scavenging potential scale was created using IC50 values. By applying our model, we classified 164 LEAPs according to their potential for •OH scavenging. Further work will focus on the experimental evaluation of the obtained model by measuring of the rate of • OH scavenging in the presence of recombinantly produced LEAPs.
C3  - Annual Meeting, SFRR-E 2021 Belgrade, Serbia, 15-18 June
T1  - Hydroxyl radical scavenging potential of the late embryogenesis abundant proteins (LEA) proteins from Ramonda serbica – in silico approach
SP  - 214
EP  - 214
UR  - https://hdl.handle.net/21.15107/rcub_cherry_4507
ER  - 
@conference{
author = "Milić Komić, Sonja and Stevanović, Strahinja and Vidović, Marija",
year = "2021",
abstract = "Ramonda serbica Panc. is a resurrection plant that can survive long desiccation periods (extreme loss of cellular water). The accumulation of late embryogenesis abundant proteins (LEAPs) is a crucial step in desiccation tolerance mechanism. Based on in vitro studies, LEAPs can be involved in antioxidative defense, ion sequestration, structural stabilization of both membranes and enzymes during freezing or drying, while by forming intracellular proteinaceous condensates they increase structural integrity and intracellular viscosity of cells during desiccation. Here we investigated the antioxidative potential of LEAPs identified by de novo transcriptomics of R. serbica, based on their primary and secondary confirmation. In our
previous work [1], we displayed the antioxidative capacity of 20 free proteogenic amino acids
(FAA) through determining their hydroxyl radical (•OH, generated in Fenton reaction) scavenging
rate by using electron paramagnetic resonance. These results served as a basis for generating a model for prediction of •OH scavenging activity for selected proteins. In addition, the model was built based on protein primary sequences, hydrophobicity, 3D structure and predicted solvent accessible area. Manually curated data for peptides and proteins with experimentally determined •OH scavenging rate were used for training and testing. The model was fed into machine learning algorithm and •OH scavenging potential scale was created using IC50 values. By applying our model, we classified 164 LEAPs according to their potential for •OH scavenging. Further work will focus on the experimental evaluation of the obtained model by measuring of the rate of • OH scavenging in the presence of recombinantly produced LEAPs.",
journal = "Annual Meeting, SFRR-E 2021 Belgrade, Serbia, 15-18 June",
title = "Hydroxyl radical scavenging potential of the late embryogenesis abundant proteins (LEA) proteins from Ramonda serbica – in silico approach",
pages = "214-214",
url = "https://hdl.handle.net/21.15107/rcub_cherry_4507"
}
Milić Komić, S., Stevanović, S.,& Vidović, M.. (2021). Hydroxyl radical scavenging potential of the late embryogenesis abundant proteins (LEA) proteins from Ramonda serbica – in silico approach. in Annual Meeting, SFRR-E 2021 Belgrade, Serbia, 15-18 June, 214-214.
https://hdl.handle.net/21.15107/rcub_cherry_4507
Milić Komić S, Stevanović S, Vidović M. Hydroxyl radical scavenging potential of the late embryogenesis abundant proteins (LEA) proteins from Ramonda serbica – in silico approach. in Annual Meeting, SFRR-E 2021 Belgrade, Serbia, 15-18 June. 2021;:214-214.
https://hdl.handle.net/21.15107/rcub_cherry_4507 .
Milić Komić, Sonja, Stevanović, Strahinja, Vidović, Marija, "Hydroxyl radical scavenging potential of the late embryogenesis abundant proteins (LEA) proteins from Ramonda serbica – in silico approach" in Annual Meeting, SFRR-E 2021 Belgrade, Serbia, 15-18 June (2021):214-214,
https://hdl.handle.net/21.15107/rcub_cherry_4507 .

Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid—Mediated Drought Response in Tomato

Živanović, Bojana; Milić Komić, Sonja; Tosti, Tomislav; Vidović, Marija; Prokić, Ljiljana; Veljović Jovanović, Sonja

(MDPI, 2020)

TY  - JOUR
AU  - Živanović, Bojana
AU  - Milić Komić, Sonja
AU  - Tosti, Tomislav
AU  - Vidović, Marija
AU  - Prokić, Ljiljana
AU  - Veljović Jovanović, Sonja
PY  - 2020
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/4266
AB  - Water deficit has a global impact on plant growth and crop yield. Climate changes are going to increase the intensity, duration and frequency of severe droughts, particularly in southern and south-eastern Europe, elevating the water scarcity issues. We aimed to assess the contribution of endogenous abscisic acid (ABA) in the protective mechanisms against water deficit, including stomatal conductance, relative water potential and the accumulation of osmoprotectants, as well as on growth parameters. To achieve that, we used a suitable model system, ABA-deficient tomato mutant, flacca and its parental line. Flacca mutant exhibited constitutively higher levels of soluble sugars (e.g., galactose, arabinose, sorbitol) and free amino acids (AAs) compared with the wild type (WT). Water deficit provoked the strong accumulation of proline in both genotypes, and total soluble sugars only in flacca. Upon re-watering, these osmolytes returned to the initial levels in both genotypes. Our results indicate that flacca compensated higher stomatal conductance with a higher constitutive level of free sugars and AAs. Additionally, we suggest that the accumulation of AAs, particularly proline and its precursors and specific branched-chain AAs in both, glucose and sucrose in flacca, and sorbitol in WT, could contribute to maintaining growth rate during water deficit and recovery in both tomato genotypes.
PB  - MDPI
T2  - Plants
T1  - Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid—Mediated Drought Response in Tomato
VL  - 9
IS  - 9
SP  - 1147
DO  - 10.3390/plants9091147
ER  - 
@article{
author = "Živanović, Bojana and Milić Komić, Sonja and Tosti, Tomislav and Vidović, Marija and Prokić, Ljiljana and Veljović Jovanović, Sonja",
year = "2020",
abstract = "Water deficit has a global impact on plant growth and crop yield. Climate changes are going to increase the intensity, duration and frequency of severe droughts, particularly in southern and south-eastern Europe, elevating the water scarcity issues. We aimed to assess the contribution of endogenous abscisic acid (ABA) in the protective mechanisms against water deficit, including stomatal conductance, relative water potential and the accumulation of osmoprotectants, as well as on growth parameters. To achieve that, we used a suitable model system, ABA-deficient tomato mutant, flacca and its parental line. Flacca mutant exhibited constitutively higher levels of soluble sugars (e.g., galactose, arabinose, sorbitol) and free amino acids (AAs) compared with the wild type (WT). Water deficit provoked the strong accumulation of proline in both genotypes, and total soluble sugars only in flacca. Upon re-watering, these osmolytes returned to the initial levels in both genotypes. Our results indicate that flacca compensated higher stomatal conductance with a higher constitutive level of free sugars and AAs. Additionally, we suggest that the accumulation of AAs, particularly proline and its precursors and specific branched-chain AAs in both, glucose and sucrose in flacca, and sorbitol in WT, could contribute to maintaining growth rate during water deficit and recovery in both tomato genotypes.",
publisher = "MDPI",
journal = "Plants",
title = "Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid—Mediated Drought Response in Tomato",
volume = "9",
number = "9",
pages = "1147",
doi = "10.3390/plants9091147"
}
Živanović, B., Milić Komić, S., Tosti, T., Vidović, M., Prokić, L.,& Veljović Jovanović, S.. (2020). Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid—Mediated Drought Response in Tomato. in Plants
MDPI., 9(9), 1147.
https://doi.org/10.3390/plants9091147
Živanović B, Milić Komić S, Tosti T, Vidović M, Prokić L, Veljović Jovanović S. Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid—Mediated Drought Response in Tomato. in Plants. 2020;9(9):1147.
doi:10.3390/plants9091147 .
Živanović, Bojana, Milić Komić, Sonja, Tosti, Tomislav, Vidović, Marija, Prokić, Ljiljana, Veljović Jovanović, Sonja, "Leaf Soluble Sugars and Free Amino Acids as Important Components of Abscisic Acid—Mediated Drought Response in Tomato" in Plants, 9, no. 9 (2020):1147,
https://doi.org/10.3390/plants9091147 . .
2
43
10
39
32

Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu

Milić Komić, Sonja

(Универзитет у Београду, Хемијски факултет, 2018)

TY  - THES
AU  - Milić Komić, Sonja
PY  - 2018
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=6270
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:18902/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=50773775
UR  - http://nardus.mpn.gov.rs/123456789/10315
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/2795
AB  - U ovoj tezi ispitivane su antioksidativne aktivnosti (AA) slobodnih aminokiselina (glicin, alanin, prolin, valin, izoleucin, leucin, fenilalanin, triptofan, tirozin, serin, treonin, asparagin, glutamin, histidin, asparaginska kiselina, glutaminska kiselina, lizin, arginin, cistein i metionin, homocistein, hidroksiprolin, norleucin, 2-aminobutanska kiselina i 3,4-dihidroksifenilalanin) u Fentonovom sistemu. Redosled reaktivnosti aminokiselina u reakciji sa hidroksil-radikalom, antioksidativne aktivnosti (HO•) bio je sledeći: Trp > norleucin > Phe, Leu > Ile > His >3,4-dihidroksifenilalanin, Arg > Val > Lys, Tyr, Pro > hidroksiprolin > α-aminobutanska kiselina > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Aminokiseline koje sadrže sumpor su u reakciji sa hidroksil-radikalom davale više različitih radikalskih vrsta koje su ispitivane EPR metodom sa spinskim hvatačima...
AB  - In this thesis antioxidative activities (AA) of free L-amino acids (glycine, alanine, proline, valine, isoleucine, leucine, phenylalanine, tryptophane, tyrosine, serine, threonine, asparagine, glutamine, histidine, aspartic acid, glutamic acid, lysine, arginine, cystein and methionine, homocysteine, hydroxyproline, norleucine, α-aminobutyric acid and 3,4-dihydroxyphenylalanine) against Fenton system-mediated hydroxyl radical (HO•) production in aqueous solution were studied. The rank order according to AA was: Trp > norleucine > Phe, Leu > Ile > His >3,4-dihydroxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydroxyproline> α-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Sulfur-containing FAA generated different secondary reactive products, which were discriminated by the means of electron paramagnetic resonance spin-trapping spectroscopy...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu
UR  - https://hdl.handle.net/21.15107/rcub_nardus_10315
ER  - 
@phdthesis{
author = "Milić Komić, Sonja",
year = "2018",
abstract = "U ovoj tezi ispitivane su antioksidativne aktivnosti (AA) slobodnih aminokiselina (glicin, alanin, prolin, valin, izoleucin, leucin, fenilalanin, triptofan, tirozin, serin, treonin, asparagin, glutamin, histidin, asparaginska kiselina, glutaminska kiselina, lizin, arginin, cistein i metionin, homocistein, hidroksiprolin, norleucin, 2-aminobutanska kiselina i 3,4-dihidroksifenilalanin) u Fentonovom sistemu. Redosled reaktivnosti aminokiselina u reakciji sa hidroksil-radikalom, antioksidativne aktivnosti (HO•) bio je sledeći: Trp > norleucin > Phe, Leu > Ile > His >3,4-dihidroksifenilalanin, Arg > Val > Lys, Tyr, Pro > hidroksiprolin > α-aminobutanska kiselina > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Aminokiseline koje sadrže sumpor su u reakciji sa hidroksil-radikalom davale više različitih radikalskih vrsta koje su ispitivane EPR metodom sa spinskim hvatačima..., In this thesis antioxidative activities (AA) of free L-amino acids (glycine, alanine, proline, valine, isoleucine, leucine, phenylalanine, tryptophane, tyrosine, serine, threonine, asparagine, glutamine, histidine, aspartic acid, glutamic acid, lysine, arginine, cystein and methionine, homocysteine, hydroxyproline, norleucine, α-aminobutyric acid and 3,4-dihydroxyphenylalanine) against Fenton system-mediated hydroxyl radical (HO•) production in aqueous solution were studied. The rank order according to AA was: Trp > norleucine > Phe, Leu > Ile > His >3,4-dihydroxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydroxyproline> α-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Sulfur-containing FAA generated different secondary reactive products, which were discriminated by the means of electron paramagnetic resonance spin-trapping spectroscopy...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu",
url = "https://hdl.handle.net/21.15107/rcub_nardus_10315"
}
Milić Komić, S.. (2018). Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_10315
Milić Komić S. Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu. in Универзитет у Београду. 2018;.
https://hdl.handle.net/21.15107/rcub_nardus_10315 .
Milić Komić, Sonja, "Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu" in Универзитет у Београду (2018),
https://hdl.handle.net/21.15107/rcub_nardus_10315 .

Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu

Milić Komić, Sonja

(Универзитет у Београду, Хемијски факултет, 2018)

TY  - THES
AU  - Milić Komić, Sonja
PY  - 2018
UR  - http://eteze.bg.ac.rs/application/showtheses?thesesId=6270
UR  - https://fedorabg.bg.ac.rs/fedora/get/o:18902/bdef:Content/download
UR  - http://vbs.rs/scripts/cobiss?command=DISPLAY&base=70036&RID=50773775
UR  - http://nardus.mpn.gov.rs/123456789/10315
UR  - https://cherry.chem.bg.ac.rs/handle/123456789/3166
AB  - U ovoj tezi ispitivane su antioksidativne aktivnosti (AA) slobodnih aminokiselina (glicin, alanin, prolin, valin, izoleucin, leucin, fenilalanin, triptofan, tirozin, serin, treonin, asparagin, glutamin, histidin, asparaginska kiselina, glutaminska kiselina, lizin, arginin, cistein i metionin, homocistein, hidroksiprolin, norleucin, 2-aminobutanska kiselina i 3,4-dihidroksifenilalanin) u Fentonovom sistemu. Redosled reaktivnosti aminokiselina u reakciji sa hidroksil-radikalom, antioksidativne aktivnosti (HO•) bio je sledeći: Trp > norleucin > Phe, Leu > Ile > His >3,4-dihidroksifenilalanin, Arg > Val > Lys, Tyr, Pro > hidroksiprolin > α-aminobutanska kiselina > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Aminokiseline koje sadrže sumpor su u reakciji sa hidroksil-radikalom davale više različitih radikalskih vrsta koje su ispitivane EPR metodom sa spinskim hvatačima...
AB  - In this thesis antioxidative activities (AA) of free L-amino acids (glycine, alanine, proline, valine, isoleucine, leucine, phenylalanine, tryptophane, tyrosine, serine, threonine, asparagine, glutamine, histidine, aspartic acid, glutamic acid, lysine, arginine, cystein and methionine, homocysteine, hydroxyproline, norleucine, α-aminobutyric acid and 3,4-dihydroxyphenylalanine) against Fenton system-mediated hydroxyl radical (HO•) production in aqueous solution were studied. The rank order according to AA was: Trp > norleucine > Phe, Leu > Ile > His >3,4-dihydroxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydroxyproline> α-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Sulfur-containing FAA generated different secondary reactive products, which were discriminated by the means of electron paramagnetic resonance spin-trapping spectroscopy...
PB  - Универзитет у Београду, Хемијски факултет
T2  - Универзитет у Београду
T1  - Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu
UR  - https://hdl.handle.net/21.15107/rcub_nardus_10315
ER  - 
@phdthesis{
author = "Milić Komić, Sonja",
year = "2018",
abstract = "U ovoj tezi ispitivane su antioksidativne aktivnosti (AA) slobodnih aminokiselina (glicin, alanin, prolin, valin, izoleucin, leucin, fenilalanin, triptofan, tirozin, serin, treonin, asparagin, glutamin, histidin, asparaginska kiselina, glutaminska kiselina, lizin, arginin, cistein i metionin, homocistein, hidroksiprolin, norleucin, 2-aminobutanska kiselina i 3,4-dihidroksifenilalanin) u Fentonovom sistemu. Redosled reaktivnosti aminokiselina u reakciji sa hidroksil-radikalom, antioksidativne aktivnosti (HO•) bio je sledeći: Trp > norleucin > Phe, Leu > Ile > His >3,4-dihidroksifenilalanin, Arg > Val > Lys, Tyr, Pro > hidroksiprolin > α-aminobutanska kiselina > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Aminokiseline koje sadrže sumpor su u reakciji sa hidroksil-radikalom davale više različitih radikalskih vrsta koje su ispitivane EPR metodom sa spinskim hvatačima..., In this thesis antioxidative activities (AA) of free L-amino acids (glycine, alanine, proline, valine, isoleucine, leucine, phenylalanine, tryptophane, tyrosine, serine, threonine, asparagine, glutamine, histidine, aspartic acid, glutamic acid, lysine, arginine, cystein and methionine, homocysteine, hydroxyproline, norleucine, α-aminobutyric acid and 3,4-dihydroxyphenylalanine) against Fenton system-mediated hydroxyl radical (HO•) production in aqueous solution were studied. The rank order according to AA was: Trp > norleucine > Phe, Leu > Ile > His >3,4-dihydroxyphenylalanine, Arg > Val > Lys, Tyr, Pro > hydroxyproline> α-aminobutyric acid > Gln, Thr, Ser > Glu, Ala, Gly, Asn, Asp. Sulfur-containing FAA generated different secondary reactive products, which were discriminated by the means of electron paramagnetic resonance spin-trapping spectroscopy...",
publisher = "Универзитет у Београду, Хемијски факултет",
journal = "Универзитет у Београду",
title = "Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu",
url = "https://hdl.handle.net/21.15107/rcub_nardus_10315"
}
Milić Komić, S.. (2018). Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu. in Универзитет у Београду
Универзитет у Београду, Хемијски факултет..
https://hdl.handle.net/21.15107/rcub_nardus_10315
Milić Komić S. Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu. in Универзитет у Београду. 2018;.
https://hdl.handle.net/21.15107/rcub_nardus_10315 .
Milić Komić, Sonja, "Redoks svojstva slobodnih aminokiselina i indola kao model-jedinjenja u Fentonovom sistemu" in Универзитет у Београду (2018),
https://hdl.handle.net/21.15107/rcub_nardus_10315 .